Flights from Detroit to South Carolina

Flight deals from Detroit to South Carolina

Looking for a cheap last-minute deal or the best return flight from Detroit to South Carolina? If you want to travel next month, return fares start from R 4,760. Find the lowest prices on one-way and return tickets right here.

Myrtle Beach.R 1,800 per passenger.Departing Wed, 8 Jul.One-way flight with Frontier Airlines.Outbound indirect flight with Frontier Airlines, departs from Detroit Wayne County on Wed, 8 Jul, arriving in Myrtle Beach International .Price includes taxes and charges.From R 1,800, select.

Greenville.R 2,096 per passenger.Departing Thu, 9 Jul.One-way flight with Frontier Airlines.Outbound indirect flight with Frontier Airlines, departs from Detroit Wayne County on Thu, 9 Jul, arriving in Greenville-Spartanburg.Price includes taxes and charges.From R 2,096, select.

Charleston.R 2,117 per passenger.Departing Tue, 28 Jul.One-way flight with Frontier Airlines.Outbound indirect flight with Frontier Airlines, departs from Detroit Wayne County on Tue, 28 Jul, arriving in Charleston.Price includes taxes and charges.From R 2,117, select.

Hilton Head Island.R 4,235 per passenger.Departing Wed, 8 Jul.One-way flight with Delta.Outbound indirect flight with Delta, departs from Detroit Wayne County on Wed, 8 Jul, arriving in Hilton Head.Price includes taxes and charges.From R 4,235, select.

Columbia.R 4,401 per passenger.Departing Thu, 25 Jun.One-way flight with Delta.Outbound indirect flight with Delta, departs from Detroit Wayne County on Thu, 25 Jun, arriving in Columbia Metropolitan.Price includes taxes and charges.From R 4,401, select.

Show more deals

Flying from Detroit to South Carolina

Arm yourself with these facts on the fly.

Cheapest flight found	R 1,800
Cheapest month to fly	July
Average flight time	1 hr, 59 mins
Cheapest airport to fly from	Detroit Wayne County
Most popular airline	WestJet

How to find cheap flights from Detroit to South Carolina

We've compared the best online travel agents and flight providers on the internet to find the cheapest plane tickets from Detroit to South Carolina. Other savvy travellers recently found return flights from R 4,381 and one-way tickets from R 1,800 one-way. Ready to join them? Here are a few tips to help you do it the smart way.

Fly from Detroit Wayne County into Charleston

At the moment, the lowest priced flight tickets to South Carolina are from Detroit Wayne County Airport to Charleston Airport.

Fly in August

We crunched the flight calendar and found the cheapest time to fly from Detroit to South Carolina is currently August.

Flex your dates for the best rates

If you’re flexible on your departure dates, you can use Skyscanner's whole month tool to find the cheapest day of the year to fly from Detroit to anywhere you choose in South Carolina.

Watch as fares rise and fall

With Price Alerts, we'll let you know when flight prices from Detroit to South Carolina go up or down so you can book when the time is just right.

Relax – these are fee-free flight tickets

With us, there are no added fees – the South Carolina to South Carolina flight price you see when you search with us is what you pay to the provider.

Frequently asked questions

What's the average Detroit to South Carolina flight price?

We looked at all of the upcoming return flights from Detroit to South Carolina we could find over the next 12 months. It looks like R 4,381 is the best price. This is good, compared to the average South Carolina ticket price of R 5,005.

What is the cheapest month to fly from Detroit to South Carolina?

The cheapest month to fly from Detroit to Greenville-Spartanburg Airport is usually June. The cheapest month to fly from Detroit to Hilton Head Airport is usually July. The cheapest month to fly from Detroit to Columbia Metropolitan Airport is usually October. And the cheapest month to fly from Detroit to Myrtle Beach International Airport is usually July.

Which upcoming date is cheapest to fly from Detroit to South Carolina on?

After crunching the numbers on our flight calendar, we found that it is currently cheapest to fly from Detroit to South Carolina on Saturday, 22 August 2026.

Are there any direct flights from Detroit to South Carolina?

Detroit Wayne County Airport offers direct flights to South Carolina.

If I'm flying from Detroit, where in South Carolina is cheapest to fly into?

If you're flying from Detroit, the cheapest city in South Carolina to fly into is Charleston. The cheapest airport serving Charleston at the moment is Charleston.