Flights from Detroit to South Carolina

Flight deals from Detroit to South Carolina

Looking for cheap tickets from Detroit to South Carolina, or a last-minute trip? Find the lowest prices on one-way and return tickets right here.

Myrtle Beach.R 1,138 per passenger.Departing Wed, 14 Jan.One-way flight with Spirit Airlines.Outbound indirect flight with Spirit Airlines, departs from Detroit Wayne County on Wed, 14 Jan, arriving in Myrtle Beach International .Price includes taxes and charges.From R 1,138, select.

Charleston.R 1,306 per passenger.Departing Fri, 9 Jan.One-way flight with Spirit Airlines.Outbound indirect flight with Spirit Airlines, departs from Detroit Wayne County on Fri, 9 Jan, arriving in Charleston.Price includes taxes and charges.From R 1,306, select.

Greenville.R 1,664 per passenger.Departing Thu, 19 Feb.One-way flight with Frontier Airlines.Outbound indirect flight with Frontier Airlines, departs from Detroit Wayne County on Thu, 19 Feb, arriving in Greenville-Spartanburg.Price includes taxes and charges.From R 1,664, select.

Columbia.R 2,025 per passenger.Departing Fri, 2 Jan.One-way flight with Frontier Airlines.Outbound indirect flight with Frontier Airlines, departs from Detroit Wayne County on Fri, 2 Jan, arriving in Columbia Metropolitan.Price includes taxes and charges.From R 2,025, select.

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Flying from Detroit to South Carolina

Arm yourself with these facts on the fly.

Cheapest flight found	R 1,138
Cheapest month to fly	January
Average flight time	2 hrs
Cheapest airport to fly from	Detroit Wayne County
Most popular airline	Delta

How to find cheap flights from Detroit to South Carolina

We've compared the best online travel agents and flight providers on the internet to find the cheapest plane tickets from Detroit to South Carolina. Other savvy travellers recently found return flights from R 2,290 and one-way tickets from R 1,138 one-way. Ready to join them? Here are a few tips to help you do it the smart way.

Fly from Detroit Wayne County into Charleston

At the moment, the lowest priced flight tickets to South Carolina are from Detroit Wayne County Airport to Charleston Airport.

Fly in January

We crunched the flight calendar and found the cheapest time to fly from Detroit to South Carolina is currently January.

Flex your dates for the best rates

If you’re flexible on your departure dates, you can use Skyscanner's whole month tool to find the cheapest day of the year to fly from Detroit to anywhere you choose in South Carolina.

Watch as fares rise and fall

With Price Alerts, we'll let you know when flight prices from Detroit to South Carolina go up or down so you can book when the time is just right.

Relax – these are fee-free flight tickets

With us, there are no added fees – the South Carolina to South Carolina flight price you see when you search with us is what you pay to the provider.

Frequently asked questions

What's the average Detroit to South Carolina flight price?

We looked at all of the upcoming return flights from Detroit to South Carolina we could find over the next 12 months. It looks like R 2,290 is the best price. This is good, compared to the average South Carolina ticket price of R 3,155.

What is the cheapest month to fly from Detroit to South Carolina?

The cheapest month to fly from Detroit to Columbia Metropolitan Airport is usually January. The cheapest month to fly from Detroit to Greenville-Spartanburg Airport is usually January. The cheapest month to fly from Detroit to Myrtle Beach International Airport is usually February. And the cheapest month to fly from Detroit to Charleston Airport is usually January.

Which upcoming date is cheapest to fly from Detroit to South Carolina on?

After crunching the numbers on our flight calendar, we found that it is currently cheapest to fly from Detroit to South Carolina on Sunday, 11 January 2026.

Are there any direct flights from Detroit to South Carolina?

Detroit Wayne County Airport offers direct flights to South Carolina.

If I'm flying from Detroit, where in South Carolina is cheapest to fly into?

If you're flying from Detroit, the cheapest city in South Carolina to fly into is Charleston. The cheapest airport serving Charleston at the moment is Charleston.