Cheap Flights from Charleston to Knoxville

Compare Charleston to Knoxville flight deals

Find the cheapest month or even day of the year to fly to Knoxville

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Find the cheapest month to fly from Charleston to Knoxville

We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Charleston to Knoxville flights are currently cheapest in September.

Charleston to Knoxville: Alternative routes

Compare routes from Charleston to Knoxville below. You may find an airport to fly into that's cheaper, faster, or easier than Knoxville.

Charleston to Knoxville: Flight information

The things to know before you go.
Cheapest flight foundR 1,876
Cheapest month to flySeptember

Finding cheap flights from Charleston to Knoxville: Frequently asked questions

The best price we found for a return flight from Charleston to Knoxville is R 3,555. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.
Currently, there are no airlines that fly direct from Charleston to Knoxville. But we found flights with one or more stops from R 3,555.
As of July 2026, there are no flights flying from Charleston to Knoxville.
The cheapest month to fly from Charleston to Knoxville is usually August.
After crunching the numbers on our flight calendar, we found that it's currently cheapest to fly from Charleston Airport to Knoxville Airport on Thursday, 13 August 2026.
No airlines currently offer direct flights between Charleston Airport and Knoxville Airport. Most routes have one or more stops.
We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to Knoxville but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.

We crunched all the numbers in our flight calendar and it looks like the cheapest time to book a flight to Knoxville is around 40 days in advance, so don’t leave your flight to the last minute.

Currently, Breeze Airways offers the cheapest flight tickets to Knoxville.

Travelling from Charleston Airport (CHS) to Knoxville Airport (TYS): what you need to know

  • Arriving two hours before an international flight and one hour ahead of a domestic departure are travel rules worth sticking to. Make sure you're at the airport on time to catch your CHS to TYS flight.

  • You can expect longer lines in popular months such as July. Arriving up to four hours ahead of international flights and two hours for domestic departures is a good idea.

  • Consider adding a stopover when booking your ticket from Charleston Airport to Knoxville Airport. Simply deselect 'Direct flights only' to break up your trip, or maybe even explore a new city along the way. Here are some options between CHS and TYS:

    • Atlanta Hartsfield-Jackson Airport

    • Charlotte Douglas Airport

    • Orlando International Airport

How to find the cheapest flights from Charleston Airport (CHS) to Knoxville Airport (TYS)

  • The cheapest price we've found for a one-way Charleston Airport to Knoxville Airport flight is R 1,873. A round-trip ticket is currently R 3,555. Depending on the availability and when you book, these fares could change.

  • To score cheap tickets from CHS to TYS, book ahead. Airlines typically offer their most competitively priced fares when flights are first made available.

  • The 'Whole month' search function shows you the cheapest flights from Charleston Airport to Knoxville Airport throughout the entire month. It's an easy way to snap up a bargain if your dates are flexible.

  • Save time looking for cheap flights from CHS to TYS by creating a Price Alert. You'll get an email or notification through the app when a new discounted fare appears.

  • Tailor your flights with filters. Pick your ideal departure and arrival times, airlines and total journey duration. You can also sort results by 'Cheapest,' 'Fastest' or 'Best' flights from Charleston Airport to Knoxville Airport.

Handy information about Charleston Airport (CHS)

  • 79% of flights that take off from Charleston Airport touch down at their destination on schedule.

  • Central Charleston to Charleston Airport is around 19 kilometres. Depending on traffic, it'll take you about 25 minutes to get there if you're driving, ride-sharing or catching a taxi.

  • Planning to take public transport? Expect a trip time of around 50 minutes.

  • Booked an early flight from Charleston Airport to Knoxville Airport? Avoid the stress of rushing to the terminal (and sneak in some extra precious sleep) by picking one of these hotels close to CHS:

Arriving at Knoxville Airport (TYS)

  • The last thing you need is a long trip to your hotel if you're landing late on a Charleston Airport to Knoxville Airport flight. Reserve one of these accommodation options near TYS instead:

  • Pick up a Knoxville Airport rental car and discover Knoxville and beyond with your own wheels. Budget, Alamo and Avis are top providers you can book with here.

  • Booking your vehicle from Knoxville Airport around three weeks ahead can help you get the best possible rate.

When to fly to Knoxville Airport (TYS)

  • October is the busiest month for flights from Charleston Airport to Knoxville Airport. To avoid the crowds, head to Knoxville in March.

  • Book your flight from Charleston Airport to Knoxville Airport for July if you'd like to go to Knoxville during its warmest month. Expect temperatures of between 17ºC (63ºF) and 32ºC (90ºF).

  • If you want to travel in cooler conditions, search for a cheap ticket from CHS to TYS in January. Temperatures average between -6ºC (21ºF) and 11ºC (52ºF) then.

Explore more of the United States

  • You've done Knoxville, now it's time to discover other parts of the United States. Travel around 451 kilometres north to Columbus to check off its top attractions. From Franklin Park Conservatory and Botanical Gardens to Whetstone Park / Park of Roses and Ohio Theatre, you'll have a full itinerary ahead.

  • Around 467 kilometres north-west of Knoxville, Indianapolis is another essential stop in the United States. Experience major highlights starting with Lucas Oil Stadium, Eiteljorg Museum and The Children's Museum of Indianapolis.

Prices shown on this page are estimated lowest prices only. Found in the last 12 days.