Cheap Flights from Columbus to Knoxville

Compare Columbus to Knoxville flight deals

Find the cheapest month or even day of the year to fly to Knoxville

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Flight deals from Columbus to Knoxville Airport

Looking for a cheap last-minute deal or the best return flight from Columbus to Knoxville Airport? If you want to travel next month, return fares start from R 4,487. Find the lowest prices on one-way and return tickets right here.

Find the cheapest month to fly from Columbus to Knoxville

We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Columbus to Knoxville flights are currently cheapest in May.

Columbus to Knoxville: Alternative routes

Compare routes from Columbus to Knoxville below. You may find an airport to fly into that's cheaper, faster, or easier than Knoxville.

Columbus to Knoxville: Flight information

The things to know before you go.
Cheapest flight foundR 1,718
Cheapest month to flyMay

Finding cheap flights from Columbus to Knoxville: Frequently asked questions

The best price we found for a return flight from Columbus to Knoxville is R 3,615. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.
Currently, there are no airlines that fly direct from Columbus to Knoxville. But we found flights with one stop from R 3,620.
As of April 2026, there are no flights flying from Columbus to Knoxville.
The cheapest month to fly from Columbus to Knoxville is usually April.
After crunching the numbers on our flight calendar, we found that it is currently cheapest to fly from Columbus to Knoxville Airport on Monday, 20 April 2026.
No airlines currently offer direct flights between Columbus and Knoxville Airport. Most routes have one or more stops.
We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to Knoxville but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.
We crunched all the numbers in our flight calendar and it looks like the cheapest time to book a flight to Knoxville is around 40 days in advance, so don’t leave your flight to the last minute.
The cheapest airline that flies to Knoxville is Frontier Airlines .

Flying from Columbus to McGhee Tyson Airport (TYS): What you need to know

  • Your trip gets off the ground at one of Columbus's main airports, John Glenn Columbus International Airport (CMH) or Rickenbacker International Airport (LCK). Check out your options for booking a flight from Columbus to McGhee Tyson Airport (TYS) setting off from either of these.

  • Knoxville's timezone is UTC-4, which is the same as Columbus. McGhee Tyson Airport is located in Knoxville.

  • To ensure you catch your flight from Columbus to TYS, leave plenty of time for things like check-in and baggage drop. Turning up two hours before international departures and one hour before domestic flights is the standard rule.

  • Peak travel periods mean busier airports, so plan to arrive even earlier. Give yourself at least two hours before a domestic flight and four hours for an international journey to keep to your schedule.

Airports in Columbus

John Glenn Columbus International Airport (CMH)

  • Travelling from central Columbus to CMH takes around 1 hour 5 minutes on public transport. If you ride-share, drive or grab a cab, you'll cover the 13 kilometres in 10 minutes or so, depending on traffic.

  • Want a leisurely start to your holiday? Stay near John Glenn Columbus International Airport. Whether you're boarding an early flight from Columbus to McGhee Tyson Airport or prefer not to feel hurried, these hotels are just what you're after:

  • Of the flights that depart from John Glenn Columbus International Airport, 79.5% touch down on time at their destination.

  • The address for CMH is 4600 International Gateway.

Rickenbacker International Airport (LCK)

  • With public transport, you can travel from central Columbus to LCK in about 1 hour 20 minutes. The terminal is roughly 26 kilometres away, and making the journey by car takes approximately 25 minutes.

  • Kick back before your Columbus to TYS flight at a hotel near Rickenbacker International Airport. Best Western Canal Winchester Inn - Columbus South East is one option where you can wake up and arrive at the airport with time to spare.

  • Rickenbacker International Airport has an on-time performance of 66.14%. This figure provides insight into how frequently flights that leave from this airport arrive at their destination on schedule.

About McGhee Tyson Airport (TYS)

  • The last thing you want is a long journey to your hotel if you're getting in late on a flight from Columbus to McGhee Tyson Airport. Stay at one of these accommodation options near TYS instead:

  • Go wherever you want, whenever you want with a McGhee Tyson Airport rental car. Pick up your wheels from Budget, Alamo or Avis and see more of Knoxville and beyond.

  • Get the best deal by booking your ride around three weeks before your Columbus to McGhee Tyson Airport flight.

  • TYS is located at 2055 Alcoa Highway.

How to find the cheapest flights from Columbus to McGhee Tyson Airport (TYS)

  • At the moment, R 1,718 is the lowest price we've found for a one-way ticket from Columbus to McGhee Tyson Airport. The cheapest price for a return flight is R 3,620. Keep in mind fares may change due to availability at the time of booking.

  • To find cheap flights from Columbus to TYS, book early. Airlines usually offer lower prices when flights first go on sale.

  • Affordable Columbus to McGhee Tyson Airport tickets are easier to find when you have flexibility in your schedule. Try using the 'Whole month' search tool to compare fares across the month and then pick the cheapest day.

  • Snapping up a cheap plane ticket from Columbus to TYS is a breeze with Price Alerts. All you need to do is create one of these automatic alerts and we'll let you know as soon as a lower fare pops up.

  • Nail down a great price on a flight from Columbus to McGhee Tyson Airport with the help of the filters. Choose your ideal arrival and departure times, airlines and number of stops. You can also sort your results by 'Cheapest,' 'Best' or 'Fastest.'

The best time to fly from Columbus to McGhee Tyson Airport (TYS)

  • February is the quietest month for flights from Columbus to McGhee Tyson Airport (TYS), while July is the busiest. Pick the best time to visit Knoxville based on whether you prefer a lively atmosphere or a more laid-back vibe.

  • The warmest month in Knoxville is July, with temperatures ranging between 17ºC (63ºF) and 32ºC (90ºF). Book your Columbus to TYS plane ticket then if you enjoy this type of weather.

  • Search for cheap tickets from Columbus to McGhee Tyson Airport in January if you'd rather travel when it's cooler. Temperatures are at their lowest then, ranging between -6ºC (21ºF) and 11ºC (52ºF).

More about Knoxville

Explore more of the United States

  • Charlotte is just one of the many cities in the United States waiting to be explored after you've experienced Knoxville. Around 290 kilometres away to the east, check out popular attractions including Bechtler Museum of Modern Art, Discovery Place and NASCAR Hall of Fame.

  • Nashville is another must-experience destination in the United States and is around 257 kilometres west of Knoxville. No journey is complete without seeing Grand Ole Opry, Country Music Hall of Fame and Museum and The Johnny Cash Museum.

Prices shown on this page are estimated lowest prices only. Found in the last 45 days.