Cheap Flights from Guayaquil to Santo Domingo

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Flight deals from Guayaquil to Santo Domingo

Looking for a cheap last-minute deal or the best return flight from Guayaquil Airport to Santo Domingo? If you want to travel next month, return fares start from R 7,233. Find the lowest prices on one-way and return tickets right here.

Find the cheapest month to fly from Guayaquil to Santo Domingo

We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Guayaquil to Santo Domingo flights are currently cheapest in May.

Alternative Guayaquil to Santo Domingo routes

Looking for the cheapest, fastest or easiest route from Guayaquil to Santo Domingo? You could fly into the following airports instead.

Guayaquil to Santo Domingo: Flight information

The things to know before you go.
Cheapest flight foundR 3,836
Cheapest month to flyMay

Finding cheap flights from Guayaquil to Santo Domingo: Frequently asked questions

There are 3 airports in Santo Domingo: La Isabela International, Santo Domingo Las Americas and Samana.
The best price we found for a return flight from Guayaquil to Santo Domingo is R 7,041. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.
Currently, there are no airlines that fly direct from Guayaquil to Santo Domingo. But we found flights with one or more stops from R 7,041.
As of May 2026, there are no flights flying from Guayaquil to Santo Domingo.
The cheapest month to fly from Guayaquil to Santo Domingo is usually May.
If you're flying from Guayaquil Airport, the cheapest airport near Santo Domingo is Santo Domingo Las Americas – which is 23.4 km away from the centre of Santo Domingo. We've found flights into this airport from R 7,041.
After crunching the numbers on our flight calendar, we found that it's currently cheapest to fly from Guayaquil Airport to Santo Domingo on Wednesday, 20 May 2026.
No airlines currently offer direct flights between Guayaquil Airport and Santo Domingo. Most routes have one or more stops.
We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to Santo Domingo but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.
We crunched all the numbers in our flight calendar and it looks like the cheapest time to book a flight to Santo Domingo is around 40 days in advance, so don’t leave your flight to the last minute.
In May, the average temperature is usually around 27°C. August is typically the warmest month in Santo Domingo, when it usually averages around 31°C. You can expect the least rain in March. The coldest month is January, with temperatures averaging 21°C. The rainiest month is September.
Currently, Avianca offers the cheapest flight tickets to Santo Domingo.

Travelling from Guayaquil Jose Joaquin de Olmedo Intl Airport (GYE) to Santo Domingo: what you need to know

  • Santo Domingo is one hour ahead of Guayaquil, where Guayaquil Jose Joaquin de Olmedo Intl Airport is located. Santo Domingo runs on the UTC-4 timezone.

  • Allow plenty of time to catch your GYE to Santo Domingo flight. As a general rule, arrive two hours before international departures and an hour ahead for domestic flights.

  • You can expect longer lines in popular months such as July. Arriving up to four hours ahead of an international flight and two hours for a domestic departure is a wise move.

  • Stopovers are the ideal opportunity to break up your trip and perhaps even tick off a new city. When searching for plane tickets from GYE to Santo Domingo, uncheck the 'Direct flights only' box to see where you can visit along the way. Top options include:

    • Miami International Airport (MIA)

    • Bogota El Dorado International Airport (BOG)

    • Panama City Tocumen International Airport (PTY)

  • Located around 5 kilometres from the centre of Guayaquil, GYE can be reached in about 20 minutes by car (depending on traffic). The journey on public transport will take roughly 35 minutes.

  • Catching an early flight from Guayaquil Jose Joaquin de Olmedo Intl Airport to Santo Domingo? Avoid rushing to the terminal (and catch some extra z's) by choosing one of these stays near GYE:

  • Guayaquil Jose Joaquin de Olmedo Intl Airport gets high marks for on-time performance. 90% of flights that depart GYE arrive at their destination without delay.

How to find the cheapest flights from Guayaquil Jose Joaquin de Olmedo Intl Airport (GYE) to Santo Domingo

  • R 3,836 is currently the best price for a one-way Guayaquil Jose Joaquin de Olmedo Intl Airport to Santo Domingo flight. Return plane tickets start at R 7,041. These prices may change depending on availability and demand.

  • Booking ahead of time is often the key to scoring a cheap flight from GYE to Santo Domingo. Airlines adjust prices based on demand, so the closer your departure date, the more you'll likely spend on your ticket.

  • If you have flexibility with your travel dates, check out the 'Whole month' search tool. It'll give you the cheapest price across every month when searching for your Guayaquil Jose Joaquin de Olmedo Intl Airport to Santo Domingo ticket.

  • Snapping up a cheap flight from GYE to Santo Domingo is easy with Price Alerts. All you need to do is set up one of these automatic notifications and we'll let you know as soon as a better deal is available.

  • Find a cheap flight from Guayaquil Jose Joaquin de Olmedo Intl Airport to Santo Domingo with the help of our filters. Choose your preferred times, number of stops and airlines, then sort the results by 'Cheapest' to see the best deals.

Airports in Santo Domingo

Santo Domingo Las Americas International Airport (SDQ)

  • The distance from Santo Domingo Las Americas International Airport (SDQ) to central Santo Domingo is roughly 29 kilometres. It'll take you about 35 minutes to get to the centre driving.

  • When travelling on public transport, expect a journey time of around 1 hour 15 minutes.

  • Look into staying at a hotel near SDQ if you have a late flight from Guayaquil Jose Joaquin de Olmedo Intl Airport to Santo Domingo. Settle into one of these accommodation options and skip the long transfer:

  • To secure the lowest price, reserve your vehicle from Santo Domingo Las Americas International Airport about one week ahead of your flight from GYE to Santo Domingo.

La Isabela Dr Joaquin Balaguer Intl Airport (JBQ)

  • Once your flight from Guayaquil Jose Joaquin de Olmedo Intl Airport to Santo Domingo has hit the tarmac, you can make your way to the city centre in around 30 minutes by car. Central Santo Domingo is roughly 23 kilometres from La Isabela Dr Joaquin Balaguer Intl Airport (JBQ).

  • If you travel by public transport, the journey will take you 50 minutes or so.

  • After stepping off your GYE to Santo Domingo flight, kick back at a hotel near JBQ. These are some great options that'll help you sink into relaxation mode:

  • Avoid the long lines and paperwork at the rental desk by having everything prearranged. Reserve your ride from JBQ a few weeks in advance so you can simply collect the keys and drive away.

Best time to go to Santo Domingo

  • December is the quietest month for flights from Guayaquil Jose Joaquin de Olmedo Intl Airport to Santo Domingo, while August is the busiest. Find the ideal time to go to Santo Domingo based on whether you want a lively atmosphere or a more laid-back vibe.

  • The warmest month in Santo Domingo is September, with temperatures ranging between 23ºC (73ºF) and 33ºC (91ºF). Book your Guayaquil Jose Joaquin de Olmedo Intl Airport to Santo Domingo plane ticket then if that's your ideal forecast.

  • February sees average temperatures of between 19ºC (66ºF) and 29ºC (84ºF). Look for a cheap ticket from GYE to Santo Domingo around that time if you like travelling in cooler conditions.

More about Santo Domingo

  • When it comes to searching for somewhere to rest your head, you'll find the top stays in Santo Domingo right here. Check out these hotels after locking in your flight from Guayaquil Jose Joaquin de Olmedo Intl Airport to Santo Domingo:

  • All great adventures should include a little sightseeing. Alcazar de Colon, Catedral Primada de las Americas and The Cathedral of the Americas are must-do's during your Santo Domingo adventure.

Explore more of the Dominican Republic

  • La Romana is just one of the many cities in the Dominican Republic waiting to be explored once you've taken in the sights of Santo Domingo. Around 105 kilometres away to the east, popular attractions include Altos de Chavon, Minitas Beach and Dye Fore Golf Course of Casa de Campo.

  • Around 161 kilometres northwest of Santo Domingo, Puerto Plata is another essential stop in the Dominican Republic. Experience major highlights starting with Long Beach, Golden Beach (Playa Dorada) and Puerto Plata Cable Car.

Prices shown on this page are estimated lowest prices only. Found in the last 45 days.