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Cheap Flights from Medellin to Guayaquil

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Find the cheapest month or even day of the year to fly to Guayaquil

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Flight deals from Medellin to Guayaquil

Looking for a cheap last-minute deal or the best return flight from Medellin to Guayaquil? Find the lowest prices on one-way and return tickets right here.
Guayaquil.R 2,932 per passenger.Departing Sun, 1 Mar.One-way flight with Copa.Outbound indirect flight with Copa, departs from Medellin Jose Maria Cordova on Sun, 1 Mar, arriving in Guayaquil.Price includes taxes and charges.From R 2,932, select.
Guayaquil.R 2,934 per passenger.Departing Sat, 21 Feb.One-way flight with Copa.Outbound indirect flight with Copa, departs from Medellin Jose Maria Cordova on Sat, 21 Feb, arriving in Guayaquil.Price includes taxes and charges.From R 2,934, select.
Guayaquil.R 2,935 per passenger.Departing Fri, 17 Apr.One-way flight with Copa.Outbound indirect flight with Copa, departs from Medellin Jose Maria Cordova on Fri, 17 Apr, arriving in Guayaquil.Price includes taxes and charges.From R 2,935, select.
Guayaquil.R 2,947 per passenger.Departing Tue, 5 May.One-way flight with Copa.Outbound indirect flight with Copa, departs from Medellin Jose Maria Cordova on Tue, 5 May, arriving in Guayaquil.Price includes taxes and charges.From R 2,947, select.
Guayaquil.R 2,984 per passenger.Departing Fri, 3 Apr.One-way flight with Avianca.Outbound direct flight with Avianca departs from Medellin Jose Maria Cordova on Fri, 3 Apr, arriving in Guayaquil.Price includes taxes and charges.From R 2,984, select.
Guayaquil.R 3,022 per passenger.Departing Wed, 4 Mar.One-way flight with Avianca.Outbound direct flight with Avianca departs from Medellin Jose Maria Cordova on Wed, 4 Mar, arriving in Guayaquil.Price includes taxes and charges.From R 3,022, select.
Guayaquil.R 3,022 per passenger.Departing Wed, 11 Feb.One-way flight with Avianca.Outbound direct flight with Avianca departs from Medellin Jose Maria Cordova on Wed, 11 Feb, arriving in Guayaquil.Price includes taxes and charges.From R 3,022, select.
Guayaquil.R 3,151 per passenger.Departing Thu, 10 Sep.One-way flight with Copa.Outbound indirect flight with Copa, departs from Medellin Jose Maria Cordova on Thu, 10 Sep, arriving in Guayaquil.Price includes taxes and charges.From R 3,151, select.

Find the cheapest month to fly from Medellin to Guayaquil

We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Medellin to Guayaquil flights are currently cheapest in March.
Feb
from R 2,938
Mar
from R 2,936
Apr
from R 2,939
May
from R 2,950
Jun
from R 3,495
Jul
from R 4,153
Aug
Find prices
Sep
from R 3,155
Oct
Find prices
Nov
Find prices
Dec
from R 3,568
Jan
from R 4,653

Direct flights from Medellin to Guayaquil

Medellin to Guayaquil: Alternative routes

Compare routes from Medellin to Guayaquil below. You may find an airport to fly into that's cheaper, faster, or easier than Guayaquil.

Guayaquil

4km from central Guayaquil
ClosestCheapest
from R 2,936
Search flights

Medellin to Guayaquil: Flight information

The things to know before you go.
Cheapest flight foundR 2,936
Cheapest month to flyMarch
Average flight time2 hrs
Most popular airlineAvianca Ecuador
Average flights per week6

Check out these Guayaquil hotels

Ready to plan your stay? Other travellers rate these Guayaquil hotels for cleanliness, service and location.
Sheraton Guayaquil Hotel
1.79 km from Guayaquil
R 1 504
Per night
TRYP by Wyndham Guayaquil Airport
1.64 km from Guayaquil
R 1 461
Per night
Wyndham Garden Guayaquil
1.93 km from Guayaquil
R 1 286
Per night
Sheraton Guayaquil Hotel
1.79 km from Guayaquil
R 1 504
Per night
TRYP by Wyndham Guayaquil Airport
1.64 km from Guayaquil
R 1 461
Per night
Wyndham Garden Guayaquil
1.93 km from Guayaquil
R 1 286
Per night
Explore top-rated hotels

Finding cheap flights from Medellin to Guayaquil: Frequently asked questions

The best price we found for a return flight from Medellin to Guayaquil is R 4,243. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.
2 hours is the average flight time from Medellin to Guayaquil.
Avianca Ecuador and Avianca fly direct from Medellin to Guayaquil.
As of February 2026, there are 6 flights per week flying from Medellin to Guayaquil.
The cheapest month to fly from Medellin to Guayaquil is usually April.
After crunching the numbers on our flight calendar, we found that it is currently cheapest to fly from Medellin to Guayaquil Airport on Friday, 17 April 2026.
Yes – the average flight time is 2 hours.
We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to Guayaquil but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.
We crunched all the numbers in our flight calendar and it looks like the cheapest time to book a flight to Guayaquil is around 40 days in advance, so don’t leave your flight to the last minute.
The cheapest airline that flies to Guayaquil is Avianca .

Travelling from Medellin to Jose Joaquin de Olmedo Airport (GYE): What you need to know

  • Medellin's main base, Jose Maria Cordova International Airport (MDE), is where plenty of awesome adventures begin. Explore the options for leaving from here when booking your flight from Medellin to Jose Joaquin de Olmedo Airport (GYE).

  • Take off on a direct Medellin to Jose Joaquin de Olmedo Airport flight and you'll be travelling for an average of 1 hour 50 minutes.

  • Guayaquil (where Jose Joaquin de Olmedo Airport is located) and Medellin share the UTC-5 timezone. With no time difference, coordinating plans between the cities is hassle-free.

  • The most popular route is from Jose Maria Cordova International Airport (MDE) to Jose Joaquin de Olmedo Airport (GYE). You can choose from 3 direct services each week. AVIANCA operates a 4:55pm departure between MDE and GYE.

  • For stress-free travel, arrive at the airport two hours ahead of international flights and one hour before domestic departures. This way, you'll have plenty of time to catch your flight from Medellin to GYE.

  • If you're jetting off during a bank holiday or other peak period, give yourself extra time. Arrive two hours ahead of domestic flights and up to four hours before international departures. Check-in and security lines will be longer.

Airports in Medellin

Jose Maria Cordova International Airport (MDE)

  • Jose Maria Cordova International Airport (MDE) is a convenient option for travelling directly to your destination. Nonstop flights from Medellin to Jose Joaquin de Olmedo Airport (GYE) can be booked from this terminal.

  • When departing from MDE, you can take a direct flight from Medellin to Jose Joaquin de Olmedo Airport with AVIANCA.

  • The airline with the highest booking numbers between MDE and GYE is AVIANCA.

  • MDE is around 24 kilometres from central Medellin. If you're catching a cab, ride-sharing or driving from the centre, it'll take you 35 minutes or so to arrive, depending on traffic conditions.

  • Have an early flight from Medellin to Jose Joaquin de Olmedo Airport? Avoid rushing to the terminal (and get some bonus sleep) by staying at one of these stays near Jose Maria Cordova International Airport:

  • When it comes to the on-time performance of Jose Maria Cordova International Airport, data shows 69.76% of flights stick to their scheduled arrival time.

Enrique Olaya Herrera Airport (EOH)

  • Break up your flight from Medellin to Jose Joaquin de Olmedo Airport with a stop at El Dorado International Airport (BOG). A major connection between Enrique Olaya Herrera Airport and GYE, it's a good opportunity to enjoy some downtime before continuing your journey.

  • EOH is around 6 kilometres from central Medellin. It takes 15 minutes or so to get to the airport by car from the city centre. Public transport takes roughly 30 minutes.

  • Start your holiday early with an additional night away from home. Before catching your Medellin to GYE flight, kick back in one of these hotels near Enrique Olaya Herrera Airport:

About Jose Joaquin de Olmedo Airport (GYE)

  • Have a late flight from Medellin to Jose Joaquin de Olmedo Airport? Don't let it rob you of real rest. Check in to one of these hotels near GYE and fast-forward to bedtime:

  • Grab a Jose Joaquin de Olmedo Airport rental car and discover Guayaquil and beyond with your own wheels. Europcar, Keddy By Europcar and Goldcar are well-known companies you can book with here.

  • Get the best deal by reserving your vehicle around four weeks ahead of your Medellin to Jose Joaquin de Olmedo Airport flight.

Getting from Jose Joaquin de Olmedo Airport (GYE) to central Guayaquil

  • Jose Joaquin de Olmedo Airport to central Guayaquil is about 5 kilometres. If you're renting a car or getting a cab, do a little research to make your trip as smooth as possible. Journey times can vary depending on traffic conditions and the time of day.

  • It takes around 20 minutes if you're using public transport.

How to find the cheapest flights from Medellin to Jose Joaquin de Olmedo Airport (GYE)

  • The lowest price we've found for a one-way ticket from Medellin to Jose Joaquin de Olmedo Airport is R 2,936. For a return flight on this route, the best price is R 4,243. Depending on the availability and when you book, these fares could change.

  • Book nine months before you want to travel. Pricing trends show that this is the ideal window for finding cheap flights from Medellin to GYE.

  • February is when you're most likely to find a fantastic deal on a Medellin to Jose Joaquin de Olmedo Airport ticket. If you need to travel at a different time of year, the 'Whole month' tool will show you the lowest prices for every month.

  • Save time looking for cheap plane tickets from Medellin to GYE by creating a Price Alert. We'll send you an email or push notification on the app when fares go down.

  • Save on your flight from Medellin to Jose Joaquin de Olmedo Airport by using filters. Select your ideal departure time, duration and airlines, then sort the results by 'Cheapest' for the best deals.

The best time to fly from Medellin to Jose Joaquin de Olmedo Airport (GYE)

  • April is the quietest month for flights from Medellin to Jose Joaquin de Olmedo Airport (GYE), while August is the most popular. Pick the best time to visit Guayaquil based on whether you want a laid-back vibe or a more bustling atmosphere.

  • The warmest month in Guayaquil is November, with temperatures ranging between 19ºC (66ºF) and 33ºC (91ºF). Book your Medellin to GYE plane ticket then if this is the type of weather you enjoy.

  • If you'd rather travel in cooler conditions, look for a cheap ticket from Medellin to Jose Joaquin de Olmedo Airport in August when temperatures are between 19ºC (66ºF) and 31ºC (88ºF).

More about Guayaquil

  • After booking your flight from Medellin to Jose Joaquin de Olmedo Airport, choose a hotel that puts you where you want to be. Make one of these accommodation options your base for exploring Guayaquil:

  • There are so many things to see and do in this city, it can be hard to work out where to begin. Amazon Rainforest, Stella Maris Galapagos Luxury Yacht and Palacio de Cristal are popular attractions which should be on any good Guayaquil itinerary.

Explore more of Ecuador

  • Quito is just one of the many cities in Ecuador waiting to be discovered after you've seen Guayaquil. Around 274 kilometres away to the north-east, popular attractions include Free Walking Tour Quito, Quito Historic Centre and Catedral Metropolitana de Quito.

  • Around 129 kilometres south-east of Guayaquil, Cuenca is another essential stop in Ecuador. Get a taste of what this destination has to offer at Inca Ruins, New Cathedral (Catedral de la Immaculada) and Quetzal Park.

Plan the rest of your trip from Medellin to Guayaquil

Prices shown on this page are estimated lowest prices only. Found in the last 45 days.