Cheap Flights from Chicago Midway to Knoxville

Compare Chicago Midway to Knoxville flight deals

Find the cheapest month or even day of the year to fly to Knoxville

Book the best Knoxville fare with no extra fees

Flight deals from Chicago Midway to Knoxville

Looking for a cheap last-minute deal or the best return flight from Chicago Midway Airport to Knoxville Airport? If you want to travel next month, return fares start from R 1,861. Find the lowest prices on one-way and return tickets right here.

Find the cheapest month to fly from Chicago Midway to Knoxville

We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Chicago Midway to Knoxville flights are currently cheapest in November.

Direct flights from Chicago Midway to Knoxville

Chicago Midway to Knoxville: Alternative routes

Compare routes from Chicago Midway to Knoxville below. You may find an airport to fly into that's cheaper, faster, or easier than Knoxville.

Chicago to Knoxville: Flight information

The things to know before you go.
Cheapest flight foundR 676
Cheapest month to flyNovember
Average flight time1 hr, 28 mins
Most popular airlineAllegiant Air
Average flights per week2

Finding cheap flights from Chicago Midway to Knoxville: Frequently asked questions

The best price we found for a return flight from Chicago Midway to Knoxville is R 1,353. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.
1 hour and 28 minutes is the average flight time from Chicago Midway to Knoxville.
Allegiant Air flies direct from Chicago Midway to Knoxville.
As of June 2026, there are 2 flights per week flying from Chicago Midway to Knoxville.
The cheapest month to fly from Chicago Midway to Knoxville is usually October.
After crunching the numbers on our flight calendar, we found that it's currently cheapest to fly from Chicago Midway Airport to Knoxville Airport on Monday, 19 October 2026.
Yes – the average flight time is 1 hour and 28 minutes.
We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to Knoxville but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.

We crunched all the numbers in our flight calendar and it looks like the cheapest time to book a flight to Knoxville is around 40 days in advance, so don’t leave your flight to the last minute.

Currently, Allegiant Air offers the cheapest flight tickets to Knoxville.

Travelling from Chicago Midway Airport (MDW) to Knoxville Airport (TYS): what you need to know

  • Book a direct flight from Chicago Midway Airport to Knoxville Airport and you'll be travelling for an average of 1 hour 30 minutes.

  • Your MDW to TYS flight won't wait if you're running late, so show up at the airport on time. Arrive up to one hour in advance for domestic flights and two hours ahead when you're travelling internationally.

  • You'll likely experience longer lines during popular months like July. Arriving up to four hours ahead of an international flight and two hours for a domestic departure will give you ample time for security and boarding.

  • Allegiant Air is your gateway to discovering Knoxville (and maybe even some other great parts of the United States!). Browse the direct flights from Chicago Midway Airport to Knoxville Airport offered by this airline.

  • Allegiant Air is the most frequently booked airline on this route.

  • Allegiant Air is the most punctual carrier offering MDW to TYS flights, with 78.95% of its services arriving as planned.

  • Think about adding a stopover when booking your ticket from Chicago Midway Airport to Knoxville Airport. Simply deselect 'Direct flights only' to break up your trip, or visit a new city along the way. Here's where you can stop between MDW and TYS:

    • Atlanta Hartsfield-Jackson Airport

    • Detroit Wayne County Airport

    • Philadelphia International Airport

How to find the cheapest flights from Chicago Midway Airport (MDW) to Knoxville Airport (TYS)

  • Currently, R 676 is the cheapest price we've seen for a one-way Chicago Midway Airport to Knoxville Airport flight. The best price for a return ticket is R 1,353. Bear in mind that fares may change due to availability at the time of booking.

  • Book one month before you travel. After looking at the numbers on our calendar, this is how far you'll want to book ahead to find cheap tickets from MDW to TYS.

  • The cheapest month for flights from Chicago Midway Airport to Knoxville Airport is June. Use the 'Whole month' tool to find the lowest airfares if you have a flexible travel schedule.

  • Save time looking for cheap flights from MDW to TYS by creating a Price Alert. You'll get an email or push notification on the app when a new low fare is offered.

  • Lock in the perfect flight for you with the help of the filters. To see the 'Cheapest,' 'Best' or 'Fastest' flights from Chicago Midway Airport to Knoxville Airport, use the 'Sort by' tool. You can also filter by arrival and departure times, airline, and journey duration.

Handy information about Chicago Midway Airport (MDW)

  • You'll find MDW at 5700 South Cicero.

  • When it comes to Chicago Midway Airport's on-time performance, data shows 76% of flights arrive within the scheduled timeframe.

  • To get to Chicago Midway Airport from central Chicago, it'll take about 25 minutes if you're planning to drive. This depends on traffic though. It's approximately 16 kilometres from the airport to the city centre.

  • You can expect a trip time of about 30 minutes when using public transport.

  • Need a handy hotel close to MDW? If you're catching an early flight from Chicago Midway Airport to Knoxville Airport, these accommodation options will have you sleeping moments from your departure lounge:

Arriving at Knoxville Airport (TYS)

When to fly to Knoxville Airport (TYS)

  • The quietest month for a flight from Chicago Midway Airport to Knoxville Airport is March, while October is the busiest. Pick the best time to go to Knoxville based on whether you prefer a faster pace or a more relaxed vibe.

  • When booking your flight from Chicago Midway Airport to Knoxville Airport, think about the kind of weather you like. July is the warmest month in Knoxville, with the temperature ranging from 17ºC (63ºF) to 32ºC (90ºF).

  • Search for cheap tickets from MDW to TYS in January if you want to travel in cooler conditions. Temperatures are at their lowest around then, ranging between -6ºC (21ºF) and 11ºC (52ºF) on average.

Explore more of the United States

  • Knoxville has plenty going for it, but there are so many other corners of the United States you'll want to see. About 451 kilometres north of Knoxville, a trip to Columbus will keep your itinerary packed. Start with popular sights like Franklin Park Conservatory and Botanical Gardens, Whetstone Park / Park of Roses and Ohio Theatre.

  • Indianapolis is another sought-after destination in the United States and is around 467 kilometres north-west of Knoxville. No journey is complete without dropping by Lucas Oil Stadium, Eiteljorg Museum and The Children's Museum of Indianapolis.

Prices shown on this page are estimated lowest prices only. Found in the last 12 days.