Cheap Flights from Mendoza to La Serena

Compare Mendoza to La Serena flight deals

Find the cheapest month or even day of the year to fly to La Serena

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Flight deals from Mendoza to La Serena

Looking for a cheap last-minute deal or the best return flight from Mendoza to La Serena? Find the lowest prices on one-way and return tickets right here.

Find the cheapest month to fly from Mendoza to La Serena

We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Mendoza to La Serena flights are currently cheapest in March.

Mendoza to La Serena: Alternative routes

Compare routes from Mendoza to La Serena below. You may find an airport to fly into that's cheaper, faster, or easier than La Serena.

Mendoza to La Serena: Flight information

The things to know before you go.
Cheapest flight foundR 1,956
Cheapest month to flyMarch

Finding cheap flights from Mendoza to La Serena: Frequently asked questions

The best price we found for a return flight from Mendoza to La Serena is R 3,702. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.
Currently, there are no airlines that fly direct from Mendoza to La Serena. But we found flights with one or more stops from R 3,702.
As of October 2025, there are no flights flying from Mendoza to La Serena.
The cheapest month to fly from Mendoza to La Serena is usually February.
After crunching the numbers on our flight calendar, we found that it's currently cheapest to fly from Mendoza Airport to La Serena Airport on Friday, 13 February 2026.
No airlines currently offer direct flights between Mendoza Airport and La Serena Airport. Most routes have one or more stops.
We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to La Serena but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.
We crunched all the numbers in our flight calendar and it looks like the cheapest time to book a flight to La Serena is around 40 days in advance, so don’t leave your flight to the last minute.
Currently, Sky Airline offers the cheapest flight tickets to La Serena.

Flying from El Plumerillo International Airport (MDZ) to La Florida Airport (LSC): what you need to know

  • For a smooth journey, turn up at the airport two hours ahead of international flights and an hour before domestic departures. This way, you can comfortably catch your MDZ to LSC flight.

  • Travelling during a peak time like July? Public holidays and other popular periods can mean longer lines and delays at security. Be extra cautious and get there up to four hours ahead of international flights and two hours before domestic departures.

  • If you want to check out a different city along the way, search for a flight with a stopover. To see all your options for tickets from El Plumerillo International Airport to La Florida Airport, deselect 'Direct flights only.' Arturo Merino Benitez Airport is a popular stop between MDZ and LSC.

How to find the cheapest flights from El Plumerillo International Airport (MDZ) to La Florida Airport (LSC)

  • The lowest price we've seen for a one-way El Plumerillo International Airport to La Florida Airport flight is R 1,956. A round-trip fare is currently R 3,702. Depending on the availability when you book, these fares could change.

  • To score cheap tickets from MDZ to LSC, book ahead. Airlines generally offer lower prices when flights are first made available.

  • The 'Whole month' search function shows you the cheapest flights from El Plumerillo International Airport to La Florida Airport throughout the entire month. It's a good way to find a bargain if your trip dates aren't set in stone.

  • Snapping up cheap flights from MDZ to LSC couldn't be easier with Price Alerts. All you need to do is create one of these automatic alerts and we'll let you know when there's a better deal.

  • Pick your ideal departure and arrival times, number of stops and airlines with the filters. Or sort your results by 'Cheapest' to find the best deals on flights from El Plumerillo International Airport to La Florida Airport.

Handy information about El Plumerillo International Airport (MDZ)

  • El Plumerillo International Airport maintains a strong on-time performance, so you're unlikely to face delays. Departures from MDZ arrive on schedule 86.17% of the time.

  • To reach El Plumerillo International Airport from central Mendoza, it takes about 20 minutes by car. Of course, this depends on traffic. It's approximately 10 kilometres from the airport to the city centre.

  • The journey when using public transport usually takes 40 minutes.

  • Get your break off to a leisurely start by staying near MDZ. Whether you've booked an early flight from El Plumerillo International Airport to La Florida Airport or want to avoid feeling rushed, these hotels are the answer:

Arriving at La Florida Airport (LSC)

  • If you're landing on a late El Plumerillo International Airport to La Florida Airport flight, nothing beats the convenience of being close to the terminal. Pick up your bags from the carousel and then be showered and resting soon after at one of these options near LSC:

  • Begin your adventure by picking up a La Florida Airport rental car. Grab a set of wheels from Street Rent a Car, gama or Budget to explore La Serena and beyond.

  • Reserving your vehicle from La Florida Airport around two weeks ahead can help you secure the lowest rate.

Getting from La Florida Airport (LSC) to central La Serena

  • La Florida Airport is approximately 5 kilometres from central La Serena. The drive time takes about 15 minutes.

  • If you're taking public transport, expect a journey of about 45 minutes.

When to fly to La Florida Airport (LSC)

  • It's time to work out your travel dates for your flight from El Plumerillo International Airport to La Florida Airport. June is the busiest month to head to La Serena. If you're after a more relaxed vibe, go in May.

  • Before locking in your flight from El Plumerillo International Airport to La Florida Airport, think about the kind of weather you enjoy. February is the warmest month in La Serena, with temperatures ranging from 14ºC (57ºF) to 24ºC (75ºF).

  • Search for cheap tickets from MDZ to LSC in July if you'd rather travel during cooler conditions. Temperatures are at their lowest around then, ranging between 8ºC (46ºF) and 20ºC (68ºF) on average.

Explore more of Chile

  • La Serena has plenty going for it, but there are so many other corners of Chile you should also see. About 402 kilometres south of La Serena, a visit to Santiago will keep your itinerary busy. Check out popular attractions like Cerro San Cristobal, La Moneda Palace and Plaza de Armas.

  • If you're interested in discovering another major stop in Chile, head for Vina del Mar, about 354 kilometres south of La Serena. La Foresta de Reñaca Park, Mirador Los Andes and Paseo Juan de Saavedra are key reasons to visit.

Prices shown on this page are estimated lowest prices only. Found in the last 45 days.