Cheap Flights from Mexico City to Santo Domingo

Compare Mexico City to Santo Domingo flight deals

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Flight deals from Mexico City to Santo Domingo

Looking for a cheap last-minute deal or the best return flight from Mexico City to Santo Domingo? If you want to travel next month, return fares start from R 5,893. Find the lowest prices on one-way and return tickets right here.

Santo Domingo.R 2,197 per passenger.Departing Fri, 25 Sep.One-way flight with Arajet.Outbound direct flight with Arajet departs from Felipe Angeles International on Fri, 25 Sep, arriving in Santo Domingo Las Americas.Price includes taxes and charges.From R 2,197, select.

Santo Domingo.R 2,200 per passenger.Departing Fri, 16 Oct.One-way flight with Arajet.Outbound direct flight with Arajet departs from Felipe Angeles International on Fri, 16 Oct, arriving in Santo Domingo Las Americas.Price includes taxes and charges.From R 2,200, select.

Santo Domingo.R 2,205 per passenger.Departing Wed, 12 Aug.One-way flight with Arajet.Outbound direct flight with Arajet departs from Felipe Angeles International on Wed, 12 Aug, arriving in Santo Domingo Las Americas.Price includes taxes and charges.From R 2,205, select.

Santo Domingo.R 2,539 per passenger.Departing Mon, 25 Jan.One-way flight with Arajet.Outbound indirect flight with Arajet, departs from Felipe Angeles International on Mon, 25 Jan, arriving in Santo Domingo Las Americas.Price includes taxes and charges.From R 2,539, select.

Santo Domingo.R 2,539 per passenger.Departing Mon, 15 Feb.One-way flight with Arajet.Outbound indirect flight with Arajet, departs from Felipe Angeles International on Mon, 15 Feb, arriving in Santo Domingo Las Americas.Price includes taxes and charges.From R 2,539, select.

Santo Domingo.R 2,779 per passenger.Departing Thu, 26 Nov.One-way flight with Arajet.Outbound direct flight with Arajet departs from Felipe Angeles International on Thu, 26 Nov, arriving in Santo Domingo Las Americas.Price includes taxes and charges.From R 2,779, select.

Santo Domingo.R 2,854 per passenger.Departing Thu, 10 Dec.One-way flight with Arajet.Outbound direct flight with Arajet departs from Felipe Angeles International on Thu, 10 Dec, arriving in Santo Domingo Las Americas.Price includes taxes and charges.From R 2,854, select.

Santo Domingo.R 3,021 per passenger.Departing Thu, 30 Jul.One-way flight with Arajet.Outbound direct flight with Arajet departs from Felipe Angeles International on Thu, 30 Jul, arriving in Santo Domingo Las Americas.Price includes taxes and charges.From R 3,021, select.

Santo Domingo.R 3,033 per passenger.Departing Thu, 14 Jan.One-way flight with Arajet.Outbound direct flight with Arajet departs from Felipe Angeles International on Thu, 14 Jan, arriving in Santo Domingo Las Americas.Price includes taxes and charges.From R 3,033, select.

Santo Domingo.R 3,045 per passenger.Departing Fri, 26 Mar.One-way flight with Arajet.Outbound direct flight with Arajet departs from Felipe Angeles International on Fri, 26 Mar, arriving in Santo Domingo Las Americas.Price includes taxes and charges.From R 3,045, select.

Santo Domingo.R 3,056 per passenger.Departing Mon, 22 Feb.One-way flight with Arajet.Outbound direct flight with Arajet departs from Felipe Angeles International on Mon, 22 Feb, arriving in Santo Domingo Las Americas.Price includes taxes and charges.From R 3,056, select.

Santo Domingo.R 3,380 per passenger.Departing Thu, 29 Apr.One-way flight with Arajet.Outbound direct flight with Arajet departs from Felipe Angeles International on Thu, 29 Apr, arriving in Santo Domingo Las Americas.Price includes taxes and charges.From R 3,380, select.

Santo Domingo.R 3,853 per passenger.Departing Wed, 9 Jun.One-way flight with Avianca.Outbound indirect flight with Avianca, departs from Mexico City Juarez International on Wed, 9 Jun, arriving in Santo Domingo Las Americas.Price includes taxes and charges.From R 3,853, select.

Santo Domingo.R 3,974 per passenger.Departing Wed, 9 Jun.One-way flight with Arajet.Outbound direct flight with Arajet departs from Felipe Angeles International on Wed, 9 Jun, arriving in Santo Domingo Las Americas.Price includes taxes and charges.From R 3,974, select.

Santo Domingo.R 5,459 per passenger.Departing Tue, 30 Jun.One-way flight with Arajet.Outbound indirect flight with Arajet, departs from Felipe Angeles International on Tue, 30 Jun, arriving in Santo Domingo Las Americas.Price includes taxes and charges.From R 5,459, select.

Find the cheapest month to fly from Mexico City to Santo Domingo

We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Mexico City to Santo Domingo flights are currently cheapest in September.

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Direct flights from Mexico City to Santo Domingo

Alternative Mexico City to Santo Domingo routes

Looking for the cheapest, fastest or easiest route from Mexico City to Santo Domingo? You could fly into the following airports instead.

Mexico City to Santo Domingo: Flight information

The things to know before you go.

Cheapest flight found	R 2,192
Cheapest month to fly	September
Average flight time	4 hrs, 22 mins
Most popular airline	Arajet
Average flights per week	20

Finding cheap flights from Mexico City to Santo Domingo: Frequently asked questions

How many airports are there in Santo Domingo?

There are 3 airports in Santo Domingo: La Isabela International, Santo Domingo Las Americas and Samana.

How much are return flights from Mexico City to Santo Domingo?

The best price we found for a return flight from Mexico City to Santo Domingo is R 3,821. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.

How long does it take to fly from Mexico City to Santo Domingo?

4 hours and 22 minutes is the average flight time from Mexico City to Santo Domingo.

Which airlines fly direct from Mexico City to Santo Domingo?

Arajet, Aeromexico and World Ticket Ltd fly direct from Mexico City to Santo Domingo.

How many flights are there a week from Mexico City to Santo Domingo?

As of June 2026, there are 20 flights per week flying from Mexico City to Santo Domingo.

When is the cheapest time to fly from Mexico City to Santo Domingo?

The cheapest month to fly from Mexico City to Santo Domingo is usually February.

Which is the cheapest airport to fly into in Santo Domingo?

If you're flying from Mexico City, the cheapest airport near Santo Domingo is Santo Domingo Las Americas – which is 23.4 km away from the centre of Santo Domingo. We've found flights into this airport from R 3,821.

Which upcoming date is cheapest to fly from Mexico City to Santo Domingo on?

After crunching the numbers on our flight calendar, we found that it is currently cheapest to fly from Mexico City to Santo Domingo on Wednesday, 24 February 2027.

Can I get a direct flight from Mexico City to Santo Domingo?

Yes – the average flight time is 4 hours and 22 minutes.

How can I get the best flight deal from Mexico City to Santo Domingo?

We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to Santo Domingo but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.

When is the best time to book flights to Santo Domingo?

We crunched all the numbers in our flight calendar and it looks like the cheapest time to book a flight to Santo Domingo is around 40 days in advance, so don’t leave your flight to the last minute.

What’s the weather like in Santo Domingo?

In June, the average temperature is usually around 27°C. August is typically the warmest month in Santo Domingo, when it usually averages around 31°C. You can expect the least rain in March. The coldest month is January, with temperatures averaging 21°C. The rainiest month is September.

Which is the cheapest airline to fly from Mexico City to Santo Domingo with?

The cheapest airline that flies to Santo Domingo is Arajet .

Travelling from Mexico City to Santo Domingo: what you need to know

Begin planning your holiday by considering where you'll catch your flight from Mexico City to Santo Domingo. Mexico City Juarez International Airport (MEX) and Felipe Angeles International Airport (NLU) are the main airports in Mexico City.
Santo Domingo Las Americas Airport (SDQ) and La Isabela International Airport (JBQ) are Santo Domingo's primary gateways.
The average duration of a direct Mexico City to Santo Domingo flight is 4 hours 20 minutes.
Santo Domingo is two hours ahead of Mexico City and observes the UTC-4 timezone.
With seven weekly flights between the two airports, Mexico City Juarez International Airport (MEX) to Santo Domingo Las Americas Airport (SDQ) is the busiest route. Hop on the earliest flight from Mexico City to Santo Domingo with Aeromexico at 00:10. If you'd like to make the most of your day before you fly, the latest flight from MEX to SDQ is with Aeromexico at 01:01.
To ensure you catch your Mexico City to Santo Domingo flight, leave plenty of time to check in and drop off your luggage. Arriving two hours ahead of international departures and an hour before domestic flights is a good rule of thumb.
During popular months like June, you'll want to get to the airport earlier. Plan to arrive two hours before a domestic departure and four hours ahead for an international flight whenever you're travelling during peak periods in general.

How to find the cheapest flights from Mexico City to Santo Domingo

Don't wait until the last moment. You're more likely to find cheap Mexico City to Santo Domingo flights if you book ahead. Airlines often offer some fantastic early bird deals.
The 'Whole month' search tool will show you the cheapest plane tickets from Mexico City to Santo Domingo across every month. It's an easy way to snap up a bargain if your travel dates are flexible.
You don't need to check back in every day to find out if fares have dropped when you set up a Price Alert. We'll tell you as soon as there's a better deal on cheap flights from Mexico City to Santo Domingo.
Select your preferred arrival and departure times, airlines and number of stops by using the filters. Or sort your Mexico City to Santo Domingo flight results by 'Best,' 'Fastest' or 'Cheapest.'

Flying from Mexico City

Mexico City Juarez International Airport (MEX)

If you're searching for a direct flight from Mexico City to Santo Domingo, you can leave from Mexico City Juarez International Airport (MEX). Fly from MEX to Santo Domingo Las Americas Airport (SDQ) in one seamless journey.
Lock in your Mexico City to Santo Domingo plane tickets with Aeromexico. This carrier is a top choice for direct flights from MEX.
We make it simple to book a Mexico City to Santo Domingo flight with a stopover. To see all your options departing from Mexico City Juarez International Airport, deselect 'Direct flights only.' Then, simply choose a flight offering a stop long enough to tour the city of your choice. Popular stopovers include:
- Miami International Airport (MIA)
- Cancun Airport (CUN)
- San Salvador Airport (SAL)
MEX is around 6 kilometres from central Mexico City. If you're ride-sharing, driving or catching a taxi from the centre, it'll take you 30 minutes or so to get there, depending on traffic. If you're using public transport, expect the travel time to be around 40 minutes.
After a stress-free start to your holiday? Stay near Mexico City Juarez International Airport. Whether you're boarding an early flight from Mexico City to Santo Domingo or just don't like being rushed, these hotels are the answer:
Mexico City Juarez International Airport maintains a solid on-time record, making delays less likely. Departures from MEX arrive at their destination as scheduled 84% of the time.

Felipe Angeles International Airport (NLU)

You can take a nonstop flight from Mexico City to Santo Domingo out of Felipe Angeles International Airport (NLU). Kick off your travels at NLU and step off the plane at Santo Domingo Las Americas Airport (SDQ).
Arajet offers direct Mexico City to Santo Domingo plane tickets from NLU. Book your preferred seat and get to your destination in a single journey.
Visit friends or family or just take a moment to stretch your legs with a stopover. If you'd like to split up your Mexico City to Santo Domingo flight, check out these options when departing from Felipe Angeles International Airport:
- Bogota Airport (BOG)
- Panama City Tocumen International Airport (PTY)
- Cancun Airport (CUN)
On public transport, you can travel from central Mexico City to NLU in around 2 hours. The terminal is roughly 40 kilometres away. Driving will take you about 55 minutes.
Get a head start on your holiday with an additional night away from home. Before your flight from Mexico City to Santo Domingo, stay in one of these hotels near Felipe Angeles International Airport:
Felipe Angeles International Airport has an on-time performance rate of 76%. This figure reflects how often flights that depart from this airport land at their destination on time.

Arriving in Santo Domingo

Santo Domingo Las Americas Airport (SDQ)

Santo Domingo Las Americas Airport (SDQ) to central Santo Domingo takes around 35 minutes by car. The centre is roughly 24 kilometres away.
It typically takes 1 hour 15 minutes to get there when travelling by public transport.
Consider booking a hotel near SDQ if you're coming in on a late flight from Mexico City to Santo Domingo. Settle into one of these accommodation options and avoid the hassle of a long transfer:
Explore without limits with a Santo Domingo Las Americas Airport rental car. Book your wheels from Final Rentals, FlexWays or INFINITY RENT and venture far and wide through Santo Domingo and beyond.
Booking your ride from Santo Domingo Las Americas Airport around one week in advance gives you the best chance of locking in a great deal.

La Isabela International Airport (JBQ)

Once your flight from Mexico City to Santo Domingo has hit the tarmac, you can reach the city centre in around 30 minutes by car. Central Santo Domingo is approximately 14 kilometres from La Isabela International Airport (JBQ).
If you're travelling on public transport, it'll take around 50 minutes.
Place the 'Do not disturb' sign on your door and relax at a hotel close to JBQ. Here are a few options where you can check in after your flight from Mexico City to Santo Domingo:
Find the perfect playlist and hit the open road in a La Isabela International Airport rental car. Grab a set of wheels from FlexWays and set off on your adventure right away.
Generally, the earlier you book, the better the prices and selection of vehicles. Lock in your ride from JBQ as soon as you know your dates.

Best time to go to Santo Domingo

It's time to choose your travel dates for your flight from Mexico City to Santo Domingo. July is the busiest month to travel to Santo Domingo. If you want a more peaceful vibe, go in March.
Lock in a Mexico City to Santo Domingo ticket departing in September if you want to experience the city during its warmest month. You can expect temperatures in Santo Domingo to range from 23ºC (73ºF) to 33ºC (91ºF).
February sees average temperatures of between 19ºC (66ºF) and 29ºC (84ºF). Look for cheap flights from Mexico City to Santo Domingo around that time if you want to travel when it's cooler.

More about Santo Domingo

When it comes to looking for somewhere to rest your head, you'll find the top stays in Santo Domingo right here. Browse these options after locking in your flight from Mexico City to Santo Domingo:
There are so many things to see and do in this city it can be hard to figure out where to start. Alcazar de Colon, Nacional Botanical Garden and Fortress of Columbus are top attractions which should be on every Santo Domingo itinerary.

Explore more of the Dominican Republic

Santo Domingo is easy to fall in love with, but there are so many other corners of the Dominican Republic waiting to be explored. Around 2 kilometres northeast of Santo Domingo, a visit to Santo Domingo Este will keep your itinerary packed. Check out popular attractions like Lago los tres ojos, Dominican Republic National Aquarium and La Cueva del Eden.
San Pedro de Macorís is another must-experience destination in the Dominican Republic and is around 64 kilometres east of Santo Domingo. No journey is complete without a visit to Pedro Mir Ecological Park, San Pedro de Macoris Boardwalk and Centro Cultural Macorisano.