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Cheap Flights from Panama City Tocumen International to Mexico City

Compare Panama City Tocumen International to Mexico City flight deals

Find the cheapest month or even day of the year to fly to Mexico City

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Flight deals from Panama City Tocumen International to Mexico City

Looking for a cheap last-minute deal or the best return flight from Panama City Tocumen International Airport to Mexico City? If you want to travel next month, return fares start from R 5,462. Find the lowest prices on one-way and return tickets right here.
Mexico City.R 3,591 per passenger.Departing Thu, 1 Oct.One-way flight with Avianca.Outbound indirect flight with Avianca, departs from Panama City Tocumen International on Thu, 1 Oct, arriving in Mexico City Juarez International.Price includes taxes and charges.From R 3,591, select.
Mexico City.R 3,622 per passenger.Departing Sun, 27 Sep.One-way flight with Copa.Outbound indirect flight with Copa, departs from Panama City Tocumen International on Sun, 27 Sep, arriving in Mexico City Juarez International.Price includes taxes and charges.From R 3,622, select.
Mexico City.R 3,652 per passenger.Departing Mon, 31 Aug.One-way flight with Avianca.Outbound indirect flight with Avianca, departs from Panama City Tocumen International on Mon, 31 Aug, arriving in Mexico City Juarez International.Price includes taxes and charges.From R 3,652, select.
Mexico City.R 3,813 per passenger.Departing Mon, 22 Feb.One-way flight with Avianca.Outbound indirect flight with Avianca, departs from Panama City Tocumen International on Mon, 22 Feb, arriving in Felipe Angeles International.Price includes taxes and charges.From R 3,813, select.
Mexico City.R 3,826 per passenger.Departing Tue, 7 Jul.One-way flight with Avianca.Outbound indirect flight with Avianca, departs from Panama City Tocumen International on Tue, 7 Jul, arriving in Felipe Angeles International.Price includes taxes and charges.From R 3,826, select.
Mexico City.R 3,826 per passenger.Departing Sat, 30 Jan.One-way flight with Avianca.Outbound indirect flight with Avianca, departs from Panama City Tocumen International on Sat, 30 Jan, arriving in Felipe Angeles International.Price includes taxes and charges.From R 3,826, select.
Mexico City.R 3,988 per passenger.Departing Sun, 8 Nov.One-way flight with Copa.Outbound indirect flight with Copa, departs from Panama City Tocumen International on Sun, 8 Nov, arriving in Mexico City Juarez International.Price includes taxes and charges.From R 3,988, select.
Mexico City.R 4,069 per passenger.Departing Fri, 11 Dec.One-way flight with Avianca.Outbound indirect flight with Avianca, departs from Panama City Tocumen International on Fri, 11 Dec, arriving in Felipe Angeles International.Price includes taxes and charges.From R 4,069, select.
Mexico City.R 4,283 per passenger.Departing Sun, 28 Jun.One-way flight with Avianca.Outbound indirect flight with Avianca, departs from Panama City Tocumen International on Sun, 28 Jun, arriving in Mexico City Juarez International.Price includes taxes and charges.From R 4,283, select.
Mexico City.R 4,471 per passenger.Departing Wed, 31 Mar.One-way flight with Avianca.Outbound indirect flight with Avianca, departs from Panama City Tocumen International on Wed, 31 Mar, arriving in Mexico City Juarez International.Price includes taxes and charges.From R 4,471, select.
Mexico City.R 4,740 per passenger.Departing Sat, 17 Apr.One-way flight with Avianca.Outbound indirect flight with Avianca, departs from Panama City Tocumen International on Sat, 17 Apr, arriving in Mexico City Juarez International.Price includes taxes and charges.From R 4,740, select.
Mexico City.R 7,080 per passenger.Departing Tue, 8 Sep.One-way flight with Copa.Outbound direct flight with Copa departs from Panama City Tocumen International on Tue, 8 Sep, arriving in Mexico City Juarez International.Price includes taxes and charges.From R 7,080, select.
Mexico City.R 7,305 per passenger.Departing Wed, 12 Aug.One-way flight with Copa.Outbound direct flight with Copa departs from Panama City Tocumen International on Wed, 12 Aug, arriving in Mexico City Juarez International.Price includes taxes and charges.From R 7,305, select.
Mexico City.R 7,992 per passenger.Departing Tue, 23 Jun.One-way flight with Copa.Outbound direct flight with Copa departs from Panama City Tocumen International on Tue, 23 Jun, arriving in Mexico City Juarez International.Price includes taxes and charges.From R 7,992, select.
Mexico City.R 8,481 per passenger.Departing Fri, 24 Jul.One-way flight with Aeromexico.Outbound direct flight with Aeromexico departs from Panama City Tocumen International on Fri, 24 Jul, arriving in Mexico City Juarez International.Price includes taxes and charges.From R 8,481, select.
Mexico City.R 8,782 per passenger.Departing Mon, 30 Nov.One-way flight with Copa.Outbound direct flight with Copa departs from Panama City Tocumen International on Mon, 30 Nov, arriving in Mexico City Juarez International.Price includes taxes and charges.From R 8,782, select.

Find the cheapest month to fly from Panama City Tocumen International to Mexico City

We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Panama City Tocumen International to Mexico City flights are currently cheapest in October.
Jun
from R 4,283
Jul
from R 3,826
Aug
from R 3,652
Sep
from R 3,622
Oct
from R 3,591
Nov
from R 3,988
Dec
from R 4,069
Jan
from R 3,826
Feb
from R 3,813
Mar
from R 4,471
Apr
from R 4,740
May
Find prices

Direct flights from Panama City Tocumen International to Mexico City

Alternative Panama City Tocumen International to Mexico City routes

Looking for the cheapest, fastest or easiest route from Panama City Tocumen International to Mexico City? You could fly into the following airports instead.

Mexico City Juarez International

6km from central Mexico City
ClosestCheapest
from R 3,591
Search flights

Felipe Angeles International

38km from central Mexico City
from R 3,813
Search flights

Toluca

47km from central Mexico City
from R 4,096
Search flights

Panama City to Mexico City: Flight information

The things to know before you go.
Cheapest flight foundR 3,591
Cheapest month to flyOctober
Average flight time5 hrs, 39 mins
Most popular airlineCopa
Average flights per week85

Finding cheap flights from Panama City Tocumen International to Mexico City: Frequently asked questions

There are 3 airports in Mexico City: Mexico City Juarez International, Felipe Angeles International and Toluca.
The best price we found for a return flight from Panama City Tocumen International to Mexico City is R 5,462. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.
5 hours and 38 minutes is the average flight time from Panama City Tocumen International to Mexico City.
Copa, Emirates and Aeromexico fly direct from Panama City Tocumen International to Mexico City.
As of June 2026, there are 85 flights per week flying from Panama City Tocumen International to Mexico City.
The cheapest month to fly from Panama City Tocumen International to Mexico City is usually July.
If you're flying from Panama City Tocumen International Airport, the cheapest airport near Mexico City is Mexico City Juarez International – which is 6.4 km away from the centre of Mexico City. We've found flights into this airport from R 5,462.
After crunching the numbers on our flight calendar, we found that it's currently cheapest to fly from Panama City Tocumen International Airport to Mexico City on Friday, 3 July 2026.
Yes – the average flight time is 5 hours and 38 minutes.
We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to Mexico City but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.
We crunched all the numbers in our flight calendar and it looks like the cheapest time to book a flight to Mexico City is around 40 days in advance, so don’t leave your flight to the last minute.
In June, the average temperature is usually around 17°C. June is typically the warmest month in Mexico City, when it usually averages around 24°C. You can expect the least rain in December. The coldest month is December, with temperatures averaging 5°C. The rainiest month is September.
Currently, Avianca and Aeromexico offer the cheapest flight tickets to Mexico City.

Travelling from Panama City Tocumen International Airport (PTY) to Mexico City: what you need to know

  • Approximately 3 hours 45 minutes is how long you can expect to be in the air on a direct flight from Panama City Tocumen International Airport to Mexico City.

  • Mexico City is one hour behind Panama City, where Panama City Tocumen International Airport is located. Mexico City observes the UTC-6 timezone.

  • With 45 weekly flights between the two airports, Panama City Tocumen International Airport (PTY) to Mexico City Benito Juarez International Airport (MEX) is the busiest route. Copa Airlines operates the earliest flight at 09:11. If you prefer to get more out of your day before jetting off, the latest flight from PTY to MEX is with Copa Airlines at 22:19.

  • Leave plenty of time to get on your PTY to Mexico City flight. It's generally best to arrive at least two hours before international departures and an hour ahead for domestic flights.

  • You can expect bigger queues in popular months like January. Arriving up to four hours ahead of an international flight and two hours for a domestic departure is a good idea.

  • Begin your trip at PTY and fly straight to Mexico City Benito Juarez International Airport (MEX). That's where you can expect to touch down when searching for Panama City Tocumen International Airport to Mexico City tickets.

  • Book your seat with Copa Airlines. This popular airline offers direct flights from Panama City Tocumen International Airport to Mexico City.

  • A stopover is the perfect opportunity to take a break from travelling and perhaps even tick off a new city. When browsing for plane tickets from PTY to Mexico City, uncheck the 'Direct flights only' box to see where you can stop along the way. Here are some popular options to consider:

    • Cancun International Airport (CUN)

    • Miguel Hidalgo y Costilla Guadalajara Intl Airport (GDL)

    • Juan Santamaria International Airport (SJO)

  • The journey from central Panama City to PTY takes about 50 minutes on public transport. If you drive, ride-share or get a taxi, you'll cover the 18 kilometres in 35 minutes or so, depending on traffic.

  • Searching for a hotel close to PTY? If you're boarding an early flight from Panama City Tocumen International Airport to Mexico City, these accommodation options put the terminal practically at your doorstep:

  • Panama City Tocumen International Airport scores top marks for on-time performance. 88% of flights that take off from PTY arrive at their destination without delay.

How to find the cheapest flights from Panama City Tocumen International Airport (PTY) to Mexico City

  • R 3,591 is the lowest price we've seen for a one-way Panama City Tocumen International Airport to Mexico City flight. A round-trip plane ticket right now is R 5,462. Depending on the availability when you book, these fares may change.

  • Book five months before you want to fly. Pricing trends show that this is the ideal window for finding cheap flights from PTY to Mexico City.

  • Organise your trip for October. That's the best month for landing an incredible deal on Panama City Tocumen International Airport to Mexico City tickets. If you're open to different travel dates, use the 'Whole month' tool to access the lowest price across every month.

  • There's no need to keep looking every day to see if fares have dropped when you create a Price Alert. We'll notify you as soon as there's an even bigger deal on cheap flights from PTY to Mexico City.

  • Find an affordable flight from Panama City Tocumen International Airport to Mexico City with the help of our filters. Choose your preferred duration, departure time and airlines, then sort the results by 'Cheapest' to see the best deals.

Airports in Mexico City

Mexico City Benito Juarez International Airport (MEX)

  • Mexico City Benito Juarez International Airport (MEX) is around 13 kilometres from central Mexico City. If you're grabbing a taxi or a ride-share, the drive takes roughly 30 minutes.

  • It typically takes 40 minutes if you're using public transport.

  • If you're coming in on a late flight from Panama City Tocumen International Airport to Mexico City, few things beat the convenience of staying near the terminal. Collect your bags from the carousel and then be showered and relaxing soon after at one of these hotels near MEX:

  • To get the lowest price, book your ride from Mexico City Benito Juarez International Airport around four weeks in advance of your flight from PTY to Mexico City.

Mexico City Felipe Angeles International Airport (NLU)

  • Once your flight from Panama City Tocumen International Airport to Mexico City has hit the runway, you can reach the city centre in around 55 minutes by car. Central Mexico City is roughly 56 kilometres from Mexico City Felipe Angeles International Airport (NLU).

  • If you choose to travel on public transport, the ride to the centre will take you 2 hours or so.

  • Verticca Hotel is one accommodation option within a short drive of NLU. Make yourself at home here after your PTY to Mexico City flight and then hang the 'Do not disturb' sign to enjoy some uninterrupted rest.

  • Snap up the best price by booking your ride from NLU one week in advance. You can also expect to have a wider selection of vehicles.

Best time to go to Mexico City

  • November is the quietest month for flights from Panama City Tocumen International Airport to Mexico City, while September is the busiest. Figure out the best time to go to Mexico City based on whether you prefer a laid-back vibe or a more bustling atmosphere.

  • When booking your Panama City Tocumen International Airport to Mexico City plane ticket, think about the weather you're most comfortable in. May is the warmest month in Mexico City, with temperatures ranging from 12ºC (54ºF) to 30ºC (86ºF).

  • January sees average temperatures of between 6ºC (43ºF) and 23ºC (73ºF). Look for a cheap ticket from PTY to Mexico City around that time if you like travelling in cooler conditions.

More about Mexico City

  • After booking your flight from Panama City Tocumen International Airport to Mexico City, find a hotel that keeps you close to what you want to see. Make one of these options your base for exploring Mexico City:

  • There are so many things to see and do in this city it can be hard to figure out where to begin. Historic Centre (Centro Historico), Zócalo and Basilica of Our Lady of Guadalupe are leading attractions which should feature on any good Mexico City itinerary.

Explore more of Mexico

  • You've done Mexico City, now it's time to explore more of Mexico. Travel around 467 kilometres west to Guadalajara to tick off its must-visit sights. From Guadalajara Cathedral to Temple of Our Lady of Guadalupe and Mural Gigante FRIDA KHALO, there's plenty to keep you busy.

  • Around 105 kilometres southeast of Mexico City, Puebla is another favourite stop in Mexico. Experience this destination's highlights firsthand at Zócalo de Puebla, Temple of Our Lady of Guadalupe and Centro Histórico de Puebla.

Plan the rest of your trip from Panama City to Mexico City

Prices shown on this page are estimated lowest prices only. Found in the last 12 days.