Cheap Flights from Panama City Tocumen International to Sao Paulo

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Flight deals from Panama City Tocumen International to Sao Paulo

Looking for a cheap last-minute deal or the best return flight from Panama City Tocumen International to Sao Paulo? Find the lowest prices on one-way and return tickets right here.

Find the cheapest month to fly from Panama City Tocumen International to Sao Paulo

We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Panama City Tocumen International to Sao Paulo flights are currently cheapest in October.

Direct flights from Panama City Tocumen International to Sao Paulo

Alternative Panama City Tocumen International to Sao Paulo routes

Looking for the cheapest, fastest or easiest route from Panama City Tocumen International to Sao Paulo? You could fly into the following airports instead.

Panama City to Sao Paulo: Flight information

The things to know before you go.
Cheapest flight foundR 3,884
Cheapest month to flyOctober
Average flight time6 hrs, 33 mins
Most popular airlineCopa
Average flights per week600

Finding cheap flights from Panama City Tocumen International to Sao Paulo: Frequently asked questions

There are 4 airports in Sao Paulo: Sao Paulo Congonhas, Sao Paulo Guarulhos, Sao Paulo Viracopos, and Sao Jose Dos Campos.
The best price we found for a return flight from Panama City Tocumen International to Sao Paulo is R 7,122. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.
6 hours and 32 minutes is the average flight time from Panama City Tocumen International to Sao Paulo.
Copa, Azul Airlines and Emirates fly direct from Panama City Tocumen International to Sao Paulo.
As of September 2025, there are 120 flights per week flying from Panama City Tocumen International to Sao Paulo.
The cheapest month to fly from Panama City Tocumen International to Sao Paulo is usually September.
If you're flying from Panama City Tocumen International Airport, the cheapest airport near Sao Paulo is Sao Paulo Guarulhos – which is 20.4 km away from the centre of Sao Paulo. We've found flights into this airport from R 7,122.
After crunching the numbers on our flight calendar, we found that it's currently cheapest to fly from Panama City Tocumen International Airport to Sao Paulo on Wednesday, 24 September 2025.
Yes – the average flight time is 6 hours and 32 minutes.
We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to Sao Paulo but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.
We crunched all the numbers in our flight calendar and it looks like the cheapest time to book a flight to Sao Paulo is around 40 days in advance, so don’t leave your flight to the last minute.
In September, the average temperature is usually around 19°C. February is typically the warmest month in Sao Paulo, when it usually averages around 27°C. You can expect the least rain in August. The coldest month is July, with temperatures averaging 12°C. The rainiest month is January.
Currently, Avianca and Copa offer the cheapest flight tickets to Sao Paulo.

Flying from Tocumen International Airport (PTY) to Sao Paulo: what you need to know

  • The average duration of a direct flight from Tocumen International Airport to Sao Paulo is 7 hours.

  • The timezone in Sao Paulo is UTC-3. The city is two hours ahead of Panama City, where Tocumen International Airport is located.

  • The most popular route is from Tocumen International Airport (PTY) to Sao Paulo-Guarulhos International Airport (GRU). Choose from 35 services every week between these two airports. If you'd like to get on your way as soon as you can, the earliest flight from PTY to GRU is the 11:50 Copa Airlines service. If you prefer travelling later, the final departure is at 22:01 with Copa Airlines.

  • For a stress-free journey, turn up at the airport two hours ahead of international flights and an hour before domestic departures. This will give you enough time to catch your PTY to Sao Paulo flight.

  • If you're travelling during a bank holiday or another peak period, give yourself extra time. A good rule is two hours before domestic flights and up to four hours before international departures. Queues at check-in and security will be longer.

  • Direct Tocumen International Airport to Sao Paulo tickets are available for booking. Sao Paulo-Guarulhos International Airport (GRU) is where you'll step off the plane.

  • Get on board with Copa Airlines. This popular carrier operates direct flights from Tocumen International Airport to Sao Paulo.

  • We make it simple to book flight tickets from PTY to Sao Paulo with a stopover. To see the options, uncheck 'Direct flights only.' Next, select a flight that has a stop long enough to tour the city of your choice. Major stopovers include:

    • El Dorado International Airport (BOG)

    • Jorge Chavez International Airport (LIM)

    • Ministro Pistarini Airport (EZE)

  • PTY is around 18 kilometres from central Panama City. If you're catching a cab, ride-sharing or driving from the centre, it'll take 20 minutes or so to get there, depending on the traffic. If you're taking public transport, expect the travel time to be around 1 hour 5 minutes.

  • Planning to catch an early flight from Tocumen International Airport to Sao Paulo? Avoid rushing to the airport (and sneak in some extra snooze time) by choosing one of these stays close to PTY:

  • 86.03% of flights departing from Tocumen International Airport reach their destination on time. Given its strong on-time performance, delays are unlikely when taking off from PTY.

How to find the cheapest flights from Tocumen International Airport (PTY) to Sao Paulo

  • R 3,891 is the cheapest price we've found for a one-way Tocumen International Airport to Sao Paulo flight. A return flight ticket right now is R 7,134. Depending on how early you book and the availability, these fares could change.

  • To secure cheap flights from PTY to Sao Paulo, reserve your journey ten months ahead of your departure.

  • The best month for finding cheap Tocumen International Airport to Sao Paulo tickets is February. Use the 'Whole month' tool to compare all available prices, then choose the dates with the lowest fares.

  • You don't need to check back constantly to see if fares have dropped when you set up a Price Alert. We'll let you know when there's an updated deal for cheap flights from PTY to Sao Paulo.

  • Tailor your trip with filters. Select your departure and arrival times, total journey duration and airlines. You can also sort the results by 'Fastest,' 'Best' or 'Cheapest' flights from Tocumen International Airport to Sao Paulo.

Airports in Sao Paulo

Sao Paulo-Guarulhos International Airport (GRU)

  • The distance from Sao Paulo-Guarulhos International Airport (GRU) to central Sao Paulo is roughly 26 kilometres. It takes around 30 minutes to get to the centre driving.

  • If you're travelling by public transport, expect a journey time of around 1 hour 20 minutes.

  • Book a hotel close to GRU if you're coming in on a late flight from Tocumen International Airport to Sao Paulo. Select one of these options and skip the long transfer:

  • Go wherever you want, whenever you want with a Sao Paulo-Guarulhos International Airport rental car. Pick up your wheels from Foco, Localiza or Movida and venture far and wide through Sao Paulo and beyond.

  • Booking your vehicle from Sao Paulo-Guarulhos International Airport around two weeks in advance of your flight from PTY to Sao Paulo can help you secure the lowest rate.

Sao Paulo/Congonhas Airport (CGH)

  • Once your flight from Tocumen International Airport to Sao Paulo has touched down, you can get to the city centre in around 15 minutes by car. Central Sao Paulo is roughly 10 kilometres from Sao Paulo/Congonhas Airport (CGH).

  • The trip will take roughly 35 minutes on public transport.

  • There are some great places to call home for the night near CGH. Settle in and get cosy after your PTY to Sao Paulo flight at one of these perfectly located options:

  • Foco, Localiza and Movida make collecting a Sao Paulo/Congonhas Airport rental car quick and easy. These reliable suppliers are located in or around the terminal and will have you on the road before long.

  • Lock in the lowest price by booking your ride from CGH three weeks ahead of time. You'll also have access to a wider range of vehicles.

Viracopos Airport (VCP)

  • Viracopos Airport (VCP) is around 97 kilometres from central Sao Paulo. It'll take you about 1 hour 15 minutes to reach the city centre in a ride-share or cab after your flight from Tocumen International Airport to Sao Paulo.

  • Public transport will take you there in around 3 hours 25 minutes.

  • If you don't want to make the journey into the centre, choose a hotel near VCP. Get comfortable at one of these stays after your PTY to Sao Paulo flight:

  • Begin your travels without worrying about how to get to your destination with a Viracopos Airport rental car. You can book your wheels with trusted names here like Foco, Localiza and Movida.

  • Plan ahead and pocket the savings. Book your vehicle from VCP four weeks before your flight from Tocumen International Airport to Sao Paulo to access the best deals.

Best time to go to Sao Paulo

  • Before you book your flights from Tocumen International Airport to Sao Paulo, consider which time of year is best for you. High season in Sao Paulo offers a bustling atmosphere and plenty of activities, while the low season means you'll get cheaper hotel rates and smaller crowds.

  • Lock in a Tocumen International Airport to Sao Paulo flight ticket with a departure in February if you're eager to experience the city during its warmest month. You can expect temperatures to range from 18ºC (64ºF) to 28ºC (82ºF).

  • July sees average temperatures of between 12ºC (54ºF) and 25ºC (77ºF). Look for a cheap ticket from PTY to Sao Paulo around that time if you like cooler conditions.

More about Sao Paulo

  • Start your Sao Paulo trip off on the right foot by choosing the ideal place to stay. Once you've booked your flight from Tocumen International Airport to Sao Paulo, browse our selection of hotels including:

  • There are so many things to see and do in this city it can be tricky to know where to begin. Ibirapuera Park, Sao Paulo Museum of Art and Avenida Paulista are leading attractions which should feature on any good Sao Paulo itinerary.

Explore more of Brazil

  • Sao Paulo is always a good idea, but there are so many other parts of Brazil just waiting to be discovered. Around 499 kilometres north-east of Sao Paulo, a trip to Belo Horizonte will keep you on the move. Start with attractions like Abilio Barreto Historical Museum, Matiz Arte Objeto and Deck Vertedouro.

  • Around 338 kilometres south-west of Sao Paulo, Curitiba is another essential stop in Brazil. Experience major highlights starting with Jardim Botanico de Curitiba, Museu Oscar Niemeyer and Largo da Ordem.

Prices shown on this page are estimated lowest prices only. Found in the last 45 days.