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Cheap Flights from Fort Myers Southwest Florida Reg to St Louis

Compare Fort Myers Southwest Florida Reg to St Louis flight deals

Find the cheapest month or even day of the year to fly to St Louis

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Flight deals from Fort Myers Southwest Florida Reg to St Louis

Looking for a cheap last-minute deal or the best return flight from Fort Myers Southwest Florida Reg Airport to St Louis Airport? If you want to travel next month, return fares start from R 5,697. Find the lowest prices on one-way and return tickets right here.
St Louis.R 1,774 per passenger.Departing Mon, 8 Jun.One-way flight with Frontier Airlines.Outbound indirect flight with Frontier Airlines, departs from Fort Myers Southwest Florida Reg on Mon, 8 Jun, arriving in St Louis.Price includes taxes and charges.From R 1,774, select.
St Louis.R 1,891 per passenger.Departing Fri, 15 May.One-way flight with Frontier Airlines.Outbound indirect flight with Frontier Airlines, departs from Fort Myers Southwest Florida Reg on Fri, 15 May, arriving in St Louis.Price includes taxes and charges.From R 1,891, select.
St Louis.R 2,956 per passenger.Departing Wed, 17 Jun.One-way flight with Southwest Airlines.Outbound direct flight with Southwest Airlines departs from Fort Myers Southwest Florida Reg on Wed, 17 Jun, arriving in St Louis.Price includes taxes and charges.From R 2,956, select.
St Louis.R 3,155 per passenger.Departing Mon, 18 May.One-way flight with Southwest Airlines.Outbound direct flight with Southwest Airlines departs from Fort Myers Southwest Florida Reg on Mon, 18 May, arriving in St Louis.Price includes taxes and charges.From R 3,155, select.
St Louis.R 3,418 per passenger.Departing Fri, 3 Jul.One-way flight with Frontier Airlines.Outbound indirect flight with Frontier Airlines, departs from Fort Myers Southwest Florida Reg on Fri, 3 Jul, arriving in St Louis.Price includes taxes and charges.From R 3,418, select.
St Louis.R 3,793 per passenger.Departing Tue, 29 Sep.One-way flight with Southwest Airlines.Outbound indirect flight with Southwest Airlines, departs from Fort Myers Southwest Florida Reg on Tue, 29 Sep, arriving in St Louis.Price includes taxes and charges.From R 3,793, select.
St Louis.R 3,797 per passenger.Departing Tue, 29 Sep.One-way flight with Southwest Airlines.Outbound direct flight with Southwest Airlines departs from Fort Myers Southwest Florida Reg on Tue, 29 Sep, arriving in St Louis.Price includes taxes and charges.From R 3,797, select.
St Louis.R 3,988 per passenger.Departing Fri, 3 Jul.One-way flight with Southwest Airlines.Outbound direct flight with Southwest Airlines departs from Fort Myers Southwest Florida Reg on Fri, 3 Jul, arriving in St Louis.Price includes taxes and charges.From R 3,988, select.
St Louis.R 3,993 per passenger.Departing Sat, 3 Oct.One-way flight with Southwest Airlines.Outbound indirect flight with Southwest Airlines, departs from Fort Myers Southwest Florida Reg on Sat, 3 Oct, arriving in St Louis.Price includes taxes and charges.From R 3,993, select.
St Louis.R 3,996 per passenger.Departing Sat, 3 Oct.One-way flight with Southwest Airlines.Outbound direct flight with Southwest Airlines departs from Fort Myers Southwest Florida Reg on Sat, 3 Oct, arriving in St Louis.Price includes taxes and charges.From R 3,996, select.
St Louis.R 3,997 per passenger.Departing Sat, 1 Aug.One-way flight with Delta.Outbound indirect flight with Delta, departs from Fort Myers Southwest Florida Reg on Sat, 1 Aug, arriving in St Louis.Price includes taxes and charges.From R 3,997, select.
St Louis.R 4,300 per passenger.Departing Sat, 1 Aug.One-way flight with Southwest Airlines.Outbound direct flight with Southwest Airlines departs from Fort Myers Southwest Florida Reg on Sat, 1 Aug, arriving in St Louis.Price includes taxes and charges.From R 4,300, select.

Find the cheapest month to fly from Fort Myers Southwest Florida Reg to St Louis

We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Fort Myers Southwest Florida Reg to St Louis flights are currently cheapest in June.
May
from R 1,891
Jun
from R 1,774
Jul
from R 3,418
Aug
from R 3,997
Sep
from R 3,793
Oct
from R 3,993
Nov
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Dec
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Jan
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Feb
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Mar
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Apr
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Direct flights from Fort Myers Southwest Florida Reg to St Louis

Fort Myers Southwest Florida Reg to St Louis: Alternative routes

Compare routes from Fort Myers Southwest Florida Reg to St Louis below. You may find an airport to fly into that's cheaper, faster, or easier than St Louis.

St Louis

20km from central St Louis
ClosestCheapest
from R 1,774
Search flights

Belleville

32km from central St Louis
from R 2,992
Search flights

Sparta Community

69km from central St Louis
Search flights

Fort Myers to St Louis: Flight information

The things to know before you go.
Cheapest flight foundR 1,774
Cheapest month to flyJune
Average flight time2 hrs, 38 mins
Most popular airlineSouthwest Airlines
Average flights per week20

Finding cheap flights from Fort Myers Southwest Florida Reg to St Louis: Frequently asked questions

The best price we found for a return flight from Fort Myers Southwest Florida Reg to St Louis is R 5,697. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.
2 hours and 38 minutes is the average flight time from Fort Myers Southwest Florida Reg to St Louis.
Southwest Airlines flies direct from Fort Myers Southwest Florida Reg to St Louis.
As of May 2026, there are 20 flights per week flying from Fort Myers Southwest Florida Reg to St Louis.
The cheapest month to fly from Fort Myers Southwest Florida Reg to St Louis is usually June.
After crunching the numbers on our flight calendar, we found that it's currently cheapest to fly from Fort Myers Southwest Florida Reg Airport to St Louis Airport on Tuesday, 9 June 2026.
Yes – the average flight time is 2 hours and 38 minutes.
We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to St Louis but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.
We crunched all the numbers in our flight calendar and it looks like the cheapest time to book a flight to St Louis is around 40 days in advance, so don’t leave your flight to the last minute.
Currently, Breeze Airways and Southwest Airlines offer the cheapest flight tickets to St Louis.

Travelling from Southwest Florida International Airport (RSW) to Lambert-St. Louis International Airport (STL): what you need to know

  • Around 2 hours 40 minutes is how long you'll be travelling on a direct flight from Southwest Florida International Airport to Lambert-St. Louis International Airport.

  • St Louis's timezone is UTC-5, which makes St Louis one hour behind Fort Myers.

  • Take your pick of 11 weekly Southwest Florida International Airport to Lambert-St. Louis International Airport flights. The 06:00 departure with Southwest Airlines is the earliest flight you can take. Southwest Airlines operates the latest service of the day at 20:25.

  • Get to the airport on time so you don't miss your RSW to STL flight. Be there at least two hours ahead for international flights and an hour early for domestic departures to avoid sprinting to your gate.

  • During popular months like October, it's a good idea to get to the airport even earlier. Plan to arrive two hours before a domestic departure and four hours ahead for international flights when you travel during peak periods in general.

  • Getting to St Louis (and then exploring more of United States!) is easy with Southwest Airlines. This popular airline has direct flights from Southwest Florida International Airport to Lambert-St. Louis International Airport.

  • The majority of passengers choose to fly with Southwest Airlines on this route.

  • With an impressive 81.25% of services arriving on schedule, Southwest Airlines is the most punctual carrier offering RSW to STL flights.

  • Think about adding a stopover when booking your ticket from Southwest Florida International Airport to Lambert-St. Louis International Airport. Just uncheck 'Direct flights only' to break up your journey, or visit a new city along the way. Check out these options between RSW and STL:

    • Hartsfield-Jackson Atlanta International Airport

    • Chicago Midway International Airport

    • Charlotte Douglas International Airport

How to find the cheapest flights from Southwest Florida International Airport (RSW) to Lambert-St. Louis International Airport (STL)

  • The lowest price we've seen for a one-way Southwest Florida International Airport to Lambert-St. Louis International Airport flight is R 1,774. A return ticket is currently R 5,697. Depending on the availability when you book, these fares may change.

  • Get cheap tickets from RSW to STL by booking at least eight months ahead. Based on our research, that's the sweet spot for finding a bargain.

  • The cheapest month for flights from Southwest Florida International Airport to Lambert-St. Louis International Airport is July. Use the 'Whole month' tool to see the lowest prices if you have flexible dates.

  • Landing cheap flights from RSW to STL is a cinch with Price Alerts. All you need to do is create one of these automatic alerts and we'll get in touch when there's a better deal.

  • Pick your preferred arrival and departure times, number of stops and airlines with the filters. Or sort your results by 'Cheapest' to find the best deals on flights from Southwest Florida International Airport to Lambert-St. Louis International Airport.

Handy information about Southwest Florida International Airport (RSW)

  • RSW is located at 11000 Terminal Access Road.

  • 77.32% of flights taking off from Southwest Florida International Airport arrive at their destination on schedule.

  • To reach Southwest Florida International Airport from central Fort Myers, it takes about 25 minutes by car. Of course, this depends on traffic conditions. It's approximately 23 kilometres from the airport to the city centre.

  • Looking for a convenient hotel near RSW? If you've booked an early flight from Southwest Florida International Airport to Lambert-St. Louis International Airport, these accommodation options will have you sleeping moments from your departure lounge:

Arriving at Lambert-St. Louis International Airport (STL)

Getting from Lambert-St. Louis International Airport (STL) to central St Louis

  • STL is located at 10701 Lambert International Blvd..

  • Lambert-St. Louis International Airport is roughly 26 kilometres from central St Louis. The drive time takes about 20 minutes.

  • When travelling by public transport, expect a journey of around 35 minutes.

When to fly to Lambert-St. Louis International Airport (STL)

  • It's time to pick your dates for your flight from Southwest Florida International Airport to Lambert-St. Louis International Airport. July is the most popular month to head to St Louis. If you like a quieter vibe, go in April.

  • Book your flight from Southwest Florida International Airport to Lambert-St. Louis International Airport for July if you'd like to explore St Louis during its warmest month. Expect temperatures of between 17ºC (63ºF) and 33ºC (91ºF).

  • January has average temperatures of between -8ºC (18ºF) and 7ºC (45ºF). Search for cheap tickets from RSW to STL sometime around then if you'd rather travel in cooler conditions.

Explore more of United States

  • St Louis has plenty to offer, but there are so many other parts of United States just waiting to be discovered. Around 418 kilometres north-east of St Louis, a visit to Chicago will fill your itinerary to the brim. Start with attractions like Millennium Park, Art Institute of Chicago and LandShark Beer Garden at Navy Pier.

  • Around 370 kilometres east of St Louis, Indianapolis is another essential stop in United States. Experience this destination's highlights firsthand at The Children's Museum of Indianapolis, Indianapolis Museum of Art and Indianapolis Zoo.

Plan the rest of your trip from Fort Myers to St Louis

Prices shown on this page are estimated lowest prices only. Found in the last 45 days.