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Cheap Flights from San Francisco International to Guayaquil

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      Travellers and cabin class, 1 Adult, Economy

      Compare San Francisco International to Guayaquil flight deals

      Find the cheapest month or even day of the year to fly to Guayaquil

      Book the best Guayaquil fare with no extra fees

      Flight deals from San Francisco International to Guayaquil

      Looking for a cheap last-minute deal or the best return flight from San Francisco International Airport to Guayaquil Airport? If you want to travel next month, return fares start from R 10,742. Find the lowest prices on one-way and return tickets right here.
      Guayaquil.R 3,979 per passenger.Departing Tue, 27 Oct.One-way flight with Frontier Airlines.Outbound indirect flight with Frontier Airlines, departs from San Francisco International on Tue, 27 Oct, arriving in Guayaquil.Price includes taxes and charges.From R 3,979, select.
      Guayaquil.R 4,193 per passenger.Departing Sun, 8 Nov.One-way flight with Frontier Airlines.Outbound indirect flight with Frontier Airlines, departs from San Francisco International on Sun, 8 Nov, arriving in Guayaquil.Price includes taxes and charges.From R 4,193, select.
      Guayaquil.R 5,387 per passenger.Departing Sat, 26 Sep.One-way flight with Frontier Airlines.Outbound indirect flight with Frontier Airlines, departs from San Francisco International on Sat, 26 Sep, arriving in Guayaquil.Price includes taxes and charges.From R 5,387, select.
      Guayaquil.R 5,790 per passenger.Departing Tue, 19 Jan.One-way flight with Frontier Airlines.Outbound indirect flight with Frontier Airlines, departs from San Francisco International on Tue, 19 Jan, arriving in Guayaquil.Price includes taxes and charges.From R 5,790, select.
      Guayaquil.R 6,097 per passenger.Departing Thu, 1 Jul.One-way flight with Delta.Outbound indirect flight with Delta, departs from San Francisco International on Thu, 1 Jul, arriving in Guayaquil.Price includes taxes and charges.From R 6,097, select.
      Guayaquil.R 6,097 per passenger.Departing Fri, 2 Apr.One-way flight with Delta.Outbound indirect flight with Delta, departs from San Francisco International on Fri, 2 Apr, arriving in Guayaquil.Price includes taxes and charges.From R 6,097, select.
      Guayaquil.R 9,787 per passenger.Departing Fri, 25 Dec.One-way flight with Copa.Outbound indirect flight with Copa, departs from San Francisco International on Fri, 25 Dec, arriving in Guayaquil.Price includes taxes and charges.From R 9,787, select.
      How did we find these deals? The deals you see here are the lowest prices for flight tickets from San Francisco International to Guayaquil found in the last 4 days, and are subject to change and availability.

      Find the cheapest month to fly from San Francisco International to Guayaquil

      We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like San Francisco International to Guayaquil flights are currently cheapest in October.
      Sep
      from R 5,387
      Oct
      from R 3,979
      Nov
      from R 4,193
      Dec
      from R 9,787
      Jan
      from R 5,790
      Feb
      Find prices
      Mar
      Find prices
      Apr
      from R 6,097
      May
      Find prices
      Jun
      Find prices
      Jul
      from R 6,097
      Aug
      Find prices

      San Francisco International to Guayaquil: Alternative routes

      Compare routes from San Francisco International to Guayaquil below. You may find an airport to fly into that's cheaper, faster, or easier than Guayaquil.

      Guayaquil

      4km from central Guayaquil
      ClosestCheapest
      from R 3,979
      Search flights

      San Francisco to Guayaquil: Flight information

      The things to know before you go.
      Cheapest flight foundR 3,979
      Cheapest month to flyOctober

      Finding cheap flights from San Francisco International to Guayaquil: Frequently asked questions

      The best price we found for a return flight from San Francisco International to Guayaquil is R 9,196. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.
      Currently, there are no airlines that fly direct from San Francisco International to Guayaquil. But we found flights with one or more stops from R 9,196.
      As of September 2026, there are no flights flying from San Francisco International to Guayaquil.
      The cheapest month to fly from San Francisco International to Guayaquil is usually January.
      After crunching the numbers on our flight calendar, we found that it's currently cheapest to fly from San Francisco International Airport to Guayaquil Airport on Monday, 18 January 2027.
      No airlines currently offer direct flights between San Francisco International Airport and Guayaquil Airport. Most routes have one or more stops.
      We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to Guayaquil but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.

      We crunched all the numbers in our flight calendar and it looks like the cheapest time to book a flight to Guayaquil is around 40 days in advance, so don’t leave your flight to the last minute.

      Currently, Copa offers the cheapest flight tickets to Guayaquil.

      Flying from San Francisco International Airport (SFO) to Guayaquil Airport (GYE): what you need to know

      • The timezone in Guayaquil is UTC-5, which is three hours ahead of San Francisco.

      • Your SFO to GYE flight won't wait if you're late, so get to the airport on time. Arrive up to one hour in advance for domestic flights and two hours ahead when you're flying internationally.

      • You'll likely experience bigger queues during popular months such as July. Arriving up to four hours in advance for an international flight and two hours for a domestic departure will give you ample time for security and boarding.

      • If you'd like to explore another city along the way, simply deselect 'Direct flights only' when searching for your ticket from San Francisco International Airport to Guayaquil Airport. Here are the most popular stopovers between SFO and GYE:

        • New York John F. Kennedy Airport

        • Miami International Airport

        • San Salvador Airport

      Handy information about San Francisco International Airport (SFO)

      • When it comes to San Francisco International Airport's on-time performance, data shows 78% of flights stick to their scheduled arrival time.

      • To get to San Francisco International Airport from central San Francisco, it'll take around 25 minutes by car. Of course, this depends on traffic. It's approximately 21 kilometres from the airport to the city centre.

      • Expect a trip time of about 35 minutes when using public transport.

      • Get your travels off to a stress-free start by staying near SFO. Whether you're catching an early flight from San Francisco International Airport to Guayaquil Airport or just don't want to be rushed, these hotels are the answer:

      Arriving at Guayaquil Airport (GYE)

      • The last thing you need is a long journey to your hotel if you're getting in late on a San Francisco International Airport to Guayaquil Airport flight. Check in to one of these accommodation options near GYE instead:

      • Fast-track your adventure by picking up a Guayaquil Airport rental car. Grab your wheels from Europcar, Keddy By Europcar or Goldcar and explore beyond Guayaquil's usual tourist stops.

      • Lock in the best deal by reserving your vehicle from Guayaquil Airport about four weeks before your trip.

      When to fly to Guayaquil Airport (GYE)

      • It's time to choose your trip dates for your flight from San Francisco International Airport to Guayaquil Airport. July is the most popular month to visit Guayaquil. If you'd like a more relaxed vibe, go in March.

      • Lock in your flight from San Francisco International Airport to Guayaquil Airport for November if you'd like to explore Guayaquil during its warmest month. You can expect temperatures of between 19ºC (66ºF) and 33ºC (91ºF).

      • Search for cheap tickets from SFO to GYE in August if you'd rather travel during cooler conditions. Temperatures are at their lowest around then, ranging between 19ºC (66ºF) and 32ºC (90ºF) on average.

      Explore more of Ecuador

      • You've seen Guayaquil, now it's time to explore other parts of Ecuador. Travel about 274 kilometres north-east to Quito to check off its must-visit sights. From Quito Historic Centre to Catedral Metropolitana de Quito and Camino de los Incas, your itinerary will be busy.

      • If you're eager to discover another well-known destination in Ecuador, head for Cuenca, about 129 kilometres south-east of Guayaquil. Inca Ruins, New Cathedral (Catedral de la Immaculada) and Old Cathedral of Cuenca are key reasons to visit.

      Plan the rest of your trip from San Francisco to Guayaquil

      Prices shown on this page are estimated lowest prices only. Found in the last 12 days.