Cheap Flights from San Francisco International to Santo Domingo

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Flight deals from San Francisco International to Santo Domingo

Looking for a cheap last-minute deal or the best return flight from San Francisco International to Santo Domingo? Find the lowest prices on one-way and return tickets right here.

Find the cheapest month to fly from San Francisco International to Santo Domingo

We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like San Francisco International to Santo Domingo flights are currently cheapest in September.

Alternative San Francisco International to Santo Domingo routes

Looking for the cheapest, fastest or easiest route from San Francisco International to Santo Domingo? You could fly into the following airports instead.

San Francisco to Santo Domingo: Flight information

The things to know before you go.
Cheapest flight foundR 3,857
Cheapest month to flySeptember

Finding cheap flights from San Francisco International to Santo Domingo: Frequently asked questions

There are 3 airports in Santo Domingo: La Isabela International, Santo Domingo Las Americas and Samana.
The best price we found for a return flight from San Francisco International to Santo Domingo is R 8,384. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.
Currently, there are no airlines that fly direct from San Francisco International to Santo Domingo. But we found flights with one or more stops from R 8,384.
As of September 2025, there are no flights flying from San Francisco International to Santo Domingo.
The cheapest month to fly from San Francisco International to Santo Domingo is usually October.
If you're flying from San Francisco International Airport, the cheapest airport near Santo Domingo is Santo Domingo Las Americas – which is 23.4 km away from the centre of Santo Domingo. We've found flights into this airport from R 8,384.
After crunching the numbers on our flight calendar, we found that it's currently cheapest to fly from San Francisco International Airport to Santo Domingo on Wednesday, 29 October 2025.
No airlines currently offer direct flights between San Francisco International Airport and Santo Domingo. Most routes have one or more stops.
We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to Santo Domingo but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.
We crunched all the numbers in our flight calendar and it looks like the cheapest time to book a flight to Santo Domingo is around 40 days in advance, so don’t leave your flight to the last minute.
In September, the average temperature is usually around 28°C. August is typically the warmest month in Santo Domingo, when it usually averages around 31°C. You can expect the least rain in March. The coldest month is January, with temperatures averaging 21°C. The rainiest month is September.
Currently, Frontier Airlines offers the cheapest flight tickets to Santo Domingo.

Flying from San Francisco International Airport (SFO) to Santo Domingo: what you need to know

  • Santo Domingo is three hours ahead of San Francisco, where San Francisco International Airport is located. Santo Domingo observes the UTC-4 timezone.

  • For hassle-free travel, arrive at the airport two hours ahead of international flights and one hour before domestic departures. That way, you can comfortably catch your SFO to Santo Domingo flight.

  • If you're jetting off during a major holiday or another peak period, allow for even more time. A good rule is two hours ahead of domestic flights and up to four hours before international departures. Lines at check-in and security will be longer.

  • We make it a breeze to book flight tickets from SFO to Santo Domingo with a stopover. To see your options, uncheck 'Direct flights only.' Next, select a flight with a stop long enough to see the sights of the city of your choice. The most sought-after stopovers include:

    • Hartsfield-Jackson Atlanta International Airport (ATL)

    • Newark Liberty International Airport (EWR)

    • Miami International Airport (MIA)

  • The journey from central San Francisco to SFO takes about 45 minutes by public transport. If you drive, ride-share or take a cab, you'll cover the 18 kilometres in 20 minutes or so, depending on traffic.

  • Planning to catch an early flight from San Francisco International Airport to Santo Domingo? Avoid rushing to the airport (and catch some extra z's) by choosing one of these hotels near SFO:

  • Of the flights that depart from San Francisco International Airport, 77.36% land on schedule at their destination.

How to find the cheapest flights from San Francisco International Airport (SFO) to Santo Domingo

  • The best price we've found for a one-way San Francisco International Airport to Santo Domingo flight is R 3,857. The cheapest price for a return flight is R 8,384. Remember fares may change due to demand at the time of booking.

  • Booking in advance is often the key to securing a cheap flight from SFO to Santo Domingo. Fares tend to rise as demand increases, so the closer your departure date, the more you'll likely spend on your ticket.

  • If you're willing to be flexible with your trip dates, check out the 'Whole month' tool. It'll find the cheapest price across each month when searching for your San Francisco International Airport to Santo Domingo ticket.

  • Snapping up a cheap flight from SFO to Santo Domingo is a breeze with Price Alerts. Simply set up one of these automatic notifications and we'll let you know as soon as there's a better deal.

  • Pick your preferred departure and arrival times, airlines and number of stops with our filters. Then, sort the results for your flight from San Francisco International Airport to Santo Domingo by 'Cheapest,' 'Best' or 'Fastest.'

Airports in Santo Domingo

Las Americas International Airport (SDQ)

  • Las Americas International Airport (SDQ) to the centre of Santo Domingo takes about 30 minutes to reach by car. The centre is roughly 32 kilometres away.

  • The last thing you need is a long journey to your hotel if you're landing late on a flight from San Francisco International Airport to Santo Domingo. Stay at one of these accommodation options near SDQ instead:

  • Get on the fast track to adventure by picking up a Las Americas International Airport rental car. Grab your wheels from Final Rentals, FlexWays or INFINITY RENT and experience the lesser-explored corners of Santo Domingo and beyond.

  • Reserving your ride from Las Americas International Airport around one week ahead of your flight from SFO to Santo Domingo can help you lock in the best possible rate.

Dr. Joaquin Balaguer International Airport (JBQ)

  • Once your flight from San Francisco International Airport to Santo Domingo has landed, you can reach the city centre in around 25 minutes by car. Central Santo Domingo is roughly 19 kilometres from Dr. Joaquin Balaguer International Airport (JBQ).

  • Micro Hotel Condo Suites is a comfortable accommodation option within a short drive of JBQ. Make yourself at home here after your SFO to Santo Domingo flight and then hang the 'Do not disturb' sign to get some rest.

  • Pick up a Dr. Joaquin Balaguer International Airport rental car and set off toward new discoveries with your own wheels. FlexWays is just moments from baggage claim, so you can drive off without missing a beat.

  • Get the vehicle you actually want, not just what's left, by reserving your ride from JBQ before your arrival. You can also avoid last-minute price surges, especially during busy airport times.

Best time to go to Santo Domingo

  • Before locking in your flights from San Francisco International Airport to Santo Domingo, consider which time of year is best for you. High season in Santo Domingo offers a lively atmosphere and plenty of activities, while the low season means you'll get cheaper hotel rates and fewer crowds.

  • When booking your San Francisco International Airport to Santo Domingo flight ticket, think about the kind of weather you prefer. September is the warmest month in Santo Domingo, with temperatures ranging from 23ºC (73ºF) to 33ºC (91ºF).

  • Look for cheap tickets from SFO to Santo Domingo in February if you'd rather travel when it's cooler. Temperatures are at their lowest then, ranging between 19ºC (66ºF) and 29ºC (84ºF) on average.

More about Santo Domingo

  • Start your Santo Domingo trip right by choosing the ideal place to stay. Once you've booked your flight from San Francisco International Airport to Santo Domingo, explore our selection of accommodation options including:

  • Every great adventure has to include some sightseeing. National Palace, Alcazar de Colon and Basilica Cathedral of Santa Maria la Menor are must-visits when exploring Santo Domingo.

Explore more of Dominican Republic

  • You've done Santo Domingo, now it's time to explore other corners of Dominican Republic. Journey around 105 kilometres east to La Romana to check off its top attractions. From Dye Fore Golf Course of Casa de Campo to Minitas Beach and La Estrella Park, your itinerary will be busy.

  • Puerto Plata is another standout destination in Dominican Republic and is around 161 kilometres north-west of Santo Domingo. No trip is complete without seeing Fortaleza San Felipe, Teleferico Puerto Plata Cable Car and Malecon Puerto Plata.

Prices shown on this page are estimated lowest prices only. Found in the last 45 days.