Cheap Flights from Santiago to Medellin

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      Travellers and cabin class, 1 Adult, Economy

      Compare Santiago to Medellin flight deals

      Find the cheapest month or even day of the year to fly to Medellin

      Book the best Medellin fare with no extra fees

      Flight deals from Santiago to Medellin

      Looking for a cheap last-minute deal or the best return flight from Santiago Airport to Medellin? If you want to travel next month, return fares start from R 6,443. Find the lowest prices on one-way and return tickets right here.

      Find the cheapest month to fly from Santiago to Medellin

      We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Santiago to Medellin flights are currently cheapest in October.

      Alternative Santiago to Medellin routes

      Looking for the cheapest, fastest or easiest route from Santiago to Medellin? You could fly into the following airports instead.

      Santiago to Medellin: Flight information

      The things to know before you go.
      Cheapest flight foundR 3,248
      Cheapest month to flyOctober

      Finding cheap flights from Santiago to Medellin: Frequently asked questions

      There are 2 airports in Medellin: Medellin Enrique Olaya Herrera and Medellin Jose Maria Cordova.
      The best price we found for a return flight from Santiago to Medellin is R 6,443. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.
      Currently, there are no airlines that fly direct from Santiago to Medellin. But we found flights with one or more stops from R 6,418.
      As of September 2026, there are no flights flying from Santiago to Medellin.
      The cheapest month to fly from Santiago to Medellin is usually October.
      If you're flying from Santiago Airport, the cheapest airport near Medellin is Medellin Jose Maria Cordova – which is 18.9 km away from the centre of Medellin. We've found flights into this airport from R 6,443.
      After crunching the numbers on our flight calendar, we found that it's currently cheapest to fly from Santiago Airport to Medellin on Saturday, 24 October 2026.
      No airlines currently offer direct flights between Santiago Airport and Medellin. Most routes have one or more stops.
      We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to Medellin but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.

      We crunched all the numbers in our flight calendar and it looks like the cheapest time to book a flight to Medellin is around 40 days in advance, so don’t leave your flight to the last minute.

      In September, the average temperature is usually around 19°C. May is typically the warmest month in Medellin, when it usually averages around 23°C. You can expect the least rain in January. The coldest month is November, with temperatures averaging 14°C. The rainiest month is April.
      Currently, Copa offers the cheapest flight tickets to Medellin.

      Flying from Cibao International Airport (STI) to Medellin: what you need to know

      • Medellin is one hour behind Santiago, where Cibao International Airport is located. Medellin runs on the UTC-5 timezone.

      • Give yourself plenty of time to make your STI to Medellin flight. Generally, it's best to arrive at least two hours before international departures and an hour ahead for domestic flights.

      • You can expect longer lines during popular months such as August. Arriving up to four hours ahead of international flights and two hours for a domestic departure is a smart move.

      • Consider adding a stopover to potentially find a cheaper plane ticket from STI to Medellin. All you need to do is uncheck 'Direct flights only' during your search. Take a break (and maybe save some cash) by stopping at one of these airports:

        • Miami International Airport (MIA)

        • Panama City Tocumen International Airport (PTY)

        • Luis Munoz Marin International Airport (SJU)

      • STI is about 13 kilometres from central Santiago. If you're ride-sharing, catching a taxi or driving from the centre, it'll take you 25 minutes or so to get there, depending on traffic conditions. If you're using public transport, expect the trip time to be around 40 minutes.

      • In search of a hotel close to STI? If you're boarding an early flight from Cibao International Airport to Medellin, these stays set you up for a seamless send-off:

      • Cibao International Airport gets high marks for its on-time performance. 80% of flights that depart STI reach their destination without delay.

      How to find the cheapest flights from Cibao International Airport (STI) to Medellin

      • R 3,248 is the lowest price we've seen for a one-way Cibao International Airport to Medellin flight. A return ticket right now is R 6,443. Depending on how early you book and the availability, these fares can change.

      • Don't wait until the last minute. You're more likely to find cheap flights from STI to Medellin if you book in advance. Airlines often offer some amazing early bird rates.

      • Finding cheap tickets from Cibao International Airport to Medellin is more likely if you're flexible with your travel dates. Try using the 'Whole month' search function to access the lowest fares across the month and score an awesome deal.

      • You don't need to check back constantly to see if fares have dropped when you set up a Price Alert. We'll notify you the moment there's an extra saving on cheap flights from STI to Medellin.

      • Tailor your trip with filters. Pick your preferred arrival and departure times, airlines and total journey duration. You can also sort the results by 'Cheapest,' 'Fastest' or 'Best' flights from Cibao International Airport to Medellin.

      Airports in Medellin

      Medellin Jose Maria Cordova Intl Airport (MDE)

      • Medellin Jose Maria Cordova Intl Airport (MDE) to central Medellin takes about 45 minutes to reach by car. The centre is roughly 32 kilometres away.

      • Getting to the centre on public transport takes about 1 hour 15 minutes.

      • The last thing you need is a lengthy journey to your hotel if you're landing late on a flight from Cibao International Airport to Medellin. Book one of these accommodation options near MDE instead:

      • Lock in the best possible rate by booking your vehicle from Medellin Jose Maria Cordova Intl Airport around one week before your flight from STI to Medellin.

      Medellin Enrique Olaya Herrera Airport (EOH)

      • Medellin Enrique Olaya Herrera Airport (EOH) is about 5 kilometres from central Medellin. Once you've disembarked your flight from Cibao International Airport to Medellin, it'll take you around 15 minutes to reach the heart of the city in a ride-share or taxi.

      • You can expect the journey to take about 25 minutes on public transport.

      • Place the 'Do not disturb' sign on your door and rest at a hotel near EOH. Here are a few options where you can tuck yourself in after your STI to Medellin flight:

      • Don't pay more than you need to. Booking your ride one week ahead of your arrival at EOH can land you a better rate.

      Best time to go to Medellin

      • January is the most popular month for flights from Cibao International Airport to Medellin. To steer clear of the crowds, head to Medellin in December.

      • Before booking a Cibao International Airport to Medellin plane ticket, think about the weather you're most comfortable in. August is the warmest month in Medellin, with temperatures ranging from 9ºC (48ºF) to 27ºC (81ºF).

      • Search for cheap tickets from STI to Medellin in December if you want to travel in cooler conditions. Temperatures are at their lowest then, ranging between 9ºC (48ºF) and 24ºC (75ºF) on average.

      More about Medellin

      • Start your Medellin trip off on the right foot by choosing the perfect place to stay. Once you've booked your flight from Cibao International Airport to Medellin, browse our range of accommodation options including:

      • Palacio de Bellas Artes and EcoParque Comuna 13 are just two of the top-rated attractions to add to your Medellin itinerary. Continue your sightseeing adventures at Museo comuna 13.

      Explore more of Colombia

      • You've seen Medellin, now it's time to discover other corners of Colombia. Journey around 241 kilometres southeast to Bogota to check off its leading attractions. From Teatro Colon Bogota to Park Simón Bolívar Bogotá City and Museum of Contemporary Art of Bogota, you'll have a packed itinerary ahead.

      • Around 322 kilometres south of Medellin, Cali is another favourite stop in Colombia. Experience this destination's highlights firsthand at Cristo Rey, El Retiro Park and Parque Simón Bolívar.

      Prices shown on this page are estimated lowest prices only. Found in the last 12 days.