Cheap Flights from Knoxville to Buffalo Niagara

Compare Knoxville to Buffalo Niagara flight deals

Find the cheapest month or even day of the year to fly to Buffalo Niagara

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Flight deals from Knoxville to Buffalo Niagara

Looking for a cheap last-minute deal or the best return flight from Knoxville to Buffalo Niagara? Find the lowest prices on one-way and return tickets right here.

Find the cheapest month to fly from Knoxville to Buffalo Niagara

We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Knoxville to Buffalo Niagara flights are currently cheapest in July.

Knoxville to Buffalo Niagara: Alternative routes

Compare routes from Knoxville to Buffalo below. You may find an airport to fly into that's cheaper, faster, or easier than Buffalo Niagara.

Knoxville to Buffalo: Flight information

The things to know before you go.
Cheapest flight foundR 4,264
Cheapest month to flyJuly

Finding cheap flights from Knoxville to Buffalo Niagara: Frequently asked questions

The best price we found for a return flight from Knoxville to Buffalo Niagara is R 4,447. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.
Currently, there are no airlines that fly direct from Knoxville to Buffalo Niagara. But we found flights with one or more stops from R 4,447.
As of June 2025, there are no flights flying from Knoxville to Buffalo Niagara.
The cheapest month to fly from Knoxville to Buffalo Niagara is usually June 2025.
After crunching the numbers on our flight calendar, we found that it's currently cheapest to fly from Knoxville Airport to Buffalo Niagara Airport on Friday, 12 September 2025.
No airlines currently offer direct flights between Knoxville Airport and Buffalo Niagara Airport. Most routes have one or more stops.
We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to Buffalo Niagara but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.
We crunched all the numbers in our flight calendar and it looks like the cheapest time to book a flight to Buffalo is around 40 days in advance, so don’t leave your flight to the last minute.
Currently, Delta offers the cheapest flight tickets to Buffalo Niagara.

Flying from McGhee Tyson Airport (TYS) to Buffalo Niagara International Airport (BUF): what you need to know

  • To ensure you get on your TYS to BUF flight, allow plenty of time to navigate the airport and find your gate. Arriving two hours ahead of international departures and an hour before domestic flights is the general rule.

  • During popular months like July, you'll want to get to the airport earlier than usual. Arrive two hours before domestic departures and four hours ahead of international flights whenever you're travelling during peak periods in general.

How to find the cheapest flights from McGhee Tyson Airport (TYS) to Buffalo Niagara International Airport (BUF)

  • R 4,264 is the best price for a one-way McGhee Tyson Airport to Buffalo Niagara International Airport flight. Return flights start from R 4,447. These fares may change based on demand and availability.

  • Don't wait until the last minute. You're more likely to get cheap tickets from TYS to BUF if you book early. Airlines often have some fantastic early bird discounts.

  • The 'Whole month' tool shows you the cheapest flights from McGhee Tyson Airport to Buffalo Niagara International Airport throughout the month. It's a great way to snap up a bargain if your dates aren't set in stone.

  • There's no need to check every day to see if fares have gone down when you create a Price Alert. We'll notify you as soon as there's a change in price on cheap flights from TYS to BUF.

  • Find the ideal flight for you with the help of the filters. To see the 'Best,' 'Cheapest' or 'Fastest' flights from McGhee Tyson Airport to Buffalo Niagara International Airport, use the 'Sort by' tool. You can also filter results by airline, departure and arrival times, and number of stops.

Handy information about McGhee Tyson Airport (TYS)

  • TYS is located at 2055 Alcoa Highway.

  • When it comes to McGhee Tyson Airport's on-time performance, data shows 78.98% of flights arrive within the expected timeframe.

  • McGhee Tyson Airport is around 23 kilometres from central Knoxville. If you're catching a cab, ride-sharing or driving from the centre, it'll take 20 minutes or so to get there, depending on the traffic.

  • Get your holiday off to a hassle-free start by staying near TYS. Whether you've booked an early flight from McGhee Tyson Airport to Buffalo Niagara International Airport or just don't want to be rushed, these stays are perfect:

Arriving at Buffalo Niagara International Airport (BUF)

  • If you're landing on a late McGhee Tyson Airport to Buffalo Niagara International Airport flight, few things beat the convenience of being close to the terminal. Grab your bags from the carousel and then be resting not long after at one of these accommodation options near BUF:

  • Grab a Buffalo Niagara International Airport rental car and discover Buffalo and beyond with your own set of wheels. Dollar, Hertz and Budget are popular outlets you can book with here.

  • To get the lowest price, book your vehicle from Buffalo Niagara International Airport around two weeks ahead.

Getting from Buffalo Niagara International Airport (BUF) to central Buffalo

  • The address for BUF is Genesee Street.

  • Buffalo Niagara International Airport to the centre of Buffalo has a drive time of around 20 minutes. It's approximately 18 kilometres away.

  • When travelling on public transport, expect a journey time of roughly 1 hour 15 minutes.

When to fly to Buffalo Niagara International Airport (BUF)

  • The quietest month for a flight from McGhee Tyson Airport to Buffalo Niagara International Airport is May, while August is the most popular. Pick the best time to visit Buffalo based on whether you prefer a more relaxed vibe or a faster pace.

  • The warmest month in Buffalo is July, with temperatures ranging between 15ºC (59ºF) and 28ºC (82ºF). Book your flights from McGhee Tyson Airport to Buffalo Niagara International Airport in this month if this is the kind of weather you like.

  • January has average temperatures of between -10ºC (14ºF) and 2ºC (36ºF). Search for cheap tickets from TYS to BUF sometime then if you like travelling in cooler conditions.

Explore more of United States

  • New York is just one of the many cities in United States waiting to be discovered once you've seen Buffalo. Around 467 kilometres away to the south-east, top sights here include Statue of Liberty, Central Park and Empire State Building.

  • If you're interested in discovering another major destination in United States, consider Philadelphia, roughly 451 kilometres south-east of Buffalo. Liberty Bell, Independence Hall and Philadelphia Museum of Art are key highlights.

Prices shown on this page are estimated lowest prices only. Found in the last 45 days.