Cheap Flights from Knoxville to Mexico City

Compare Knoxville to Mexico City flight deals

Find the cheapest month or even day of the year to fly to Mexico City

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Find the cheapest month to fly from Knoxville to Mexico City

We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Knoxville to Mexico City flights are currently cheapest in December.

Alternative Knoxville to Mexico City routes

Looking for the cheapest, fastest or easiest route from Knoxville to Mexico City? You could fly into the following airports instead.

Knoxville to Mexico City: Flight information

The things to know before you go.
Cheapest flight foundR 2,642
Cheapest month to flyDecember

Finding cheap flights from Knoxville to Mexico City: Frequently asked questions

There are 3 airports in Mexico City: Mexico City Juarez International, Felipe Angeles International and Toluca.
The best price we found for a return flight from Knoxville to Mexico City is R 7,667. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.
Currently, there are no airlines that fly direct from Knoxville to Mexico City. But we found flights with one or more stops from R 7,667.
As of October 2025, there are no flights flying from Knoxville to Mexico City.
The cheapest month to fly from Knoxville to Mexico City is usually November.
If you're flying from Knoxville Airport, the cheapest airport near Mexico City is Mexico City Juarez International – which is 6.4 km away from the centre of Mexico City. We've found flights into this airport from R 7,667.
After crunching the numbers on our flight calendar, we found that it's currently cheapest to fly from Knoxville Airport to Mexico City on Monday, 24 November 2025.
No airlines currently offer direct flights between Knoxville Airport and Mexico City. Most routes have one or more stops.
We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to Mexico City but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.
We crunched all the numbers in our flight calendar and it looks like the cheapest time to book a flight to Mexico City is around 40 days in advance, so don’t leave your flight to the last minute.
In October, the average temperature is usually around 14°C. June is typically the warmest month in Mexico City, when it usually averages around 24°C. You can expect the least rain in December. The coldest month is December, with temperatures averaging 5°C. The rainiest month is September.
Currently, Allegiant Air offers the cheapest flight tickets to Mexico City.

Flying from McGhee Tyson Airport (TYS) to Mexico City: what you need to know

  • McGhee Tyson Airport is located in Knoxville. Based in the UTC-6 timezone, Mexico City is two hours behind Knoxville.

  • For stress-free travel, arrive at the airport two hours ahead of international flights and an hour before domestic departures. This ensures you have enough time to board your TYS to Mexico City flight.

  • Taking off during a peak period like a bank holiday? Expect longer lines at security and check-in. Give yourself extra leeway and arrive up to four hours before international flights and two hours ahead of domestic departures.

  • Central Knoxville to TYS is around 18 kilometres. Depending on traffic, it'll take about 20 minutes to get there if you're catching a cab, ride-sharing or driving.

  • Want a stress-free start to your trip? Stay near TYS. Whether you're catching an early flight from McGhee Tyson Airport to Mexico City or want to avoid feeling rushed, these hotels are worth a look:

  • Of the departures from McGhee Tyson Airport, 78.98% touch down on time at their destination.

  • TYS is located at 2055 Alcoa Highway.

How to find the cheapest flights from McGhee Tyson Airport (TYS) to Mexico City

  • The best price we've seen for a one-way McGhee Tyson Airport to Mexico City flight is R 2,642. The cheapest price for a return flight is R 7,667. Remember fares can change due to demand at the time of booking.

  • Booking early is often the key to locking in a cheap flight from TYS to Mexico City. Fares tend to rise as seats fill up, so the closer your departure date, the more you'll likely spend on your ticket.

  • Scoring cheap tickets from McGhee Tyson Airport to Mexico City is easier if you're flexible with your trip dates. Use the 'Whole month' function to access the lowest prices across each month and walk away with a fantastic deal.

  • You don't need to check in daily to find out if fares have dropped when you create a Price Alert. We'll update you as soon as there's an extra saving on cheap flights from TYS to Mexico City.

  • Select your preferred arrival and departure times, number of stops and airlines with our filters. Then, sort the results for your flight from McGhee Tyson Airport to Mexico City by 'Fastest,' 'Best' or 'Cheapest.'

Airports in Mexico City

Benito Juarez International Airport (MEX)

  • Benito Juarez International Airport (MEX) to central Mexico City takes about 25 minutes to reach by car. The centre is roughly 8 kilometres away.

  • Travelling on public transport typically takes 55 minutes.

  • If you're coming in on a late flight from McGhee Tyson Airport to Mexico City, few things beat the convenience of staying close to the terminal. Grab your bags from the carousel and then be showered and resting not long after at one of these accommodation options near MEX:

  • Grab a Benito Juarez International Airport rental car and discover Mexico City and beyond with your own wheels. INFINITY RENT, MEX and America are leading providers you can book with here.

  • Reserving your vehicle from Benito Juarez International Airport about four weeks in advance of your flight from TYS to Mexico City can help you lock in the best possible rate.

Santa Lucia Air Force Base Airport (NLU)

  • Once your flight from McGhee Tyson Airport to Mexico City has touched down, you can reach the city centre in about 55 minutes by car. Central Mexico City is roughly 40 kilometres from Santa Lucia Air Force Base Airport (NLU).

  • If you're catching public transport, it'll take around 1 hour 45 minutes.

  • Verticca Hotel is one accommodation option within a short drive of NLU. Make yourself at home here after your TYS to Mexico City flight and then put up the 'Do not disturb' sign to enjoy some uninterrupted rest.

  • Forget about public transport schedules or long cab lines. Grab a Santa Lucia Air Force Base Airport rental car and let the journey unfold your way. Check out the rates and availability from Europcar, MEX and Keddy By Europcar.

  • Get first dibs on the best options. Securing your ride from NLU one week in advance often means better prices and a wider range of vehicles.

Best time to go to Mexico City

  • Travel to Mexico City in peak season if you want a lively atmosphere, but remember that hotel prices are usually higher. Alternatively, book your flights from McGhee Tyson Airport to Mexico City during the off-season when prices are cheaper and crowds are smaller.

  • The warmest month in Mexico City is April, with temperatures ranging between 10ºC (50ºF) and 28ºC (82ºF). Book your McGhee Tyson Airport to Mexico City flight ticket then if that's your idea of comfortable weather.

  • Search for cheap tickets from TYS to Mexico City in January if you'd rather travel during cooler conditions. Temperatures are at their lowest then, ranging between 6ºC (43ºF) and 23ºC (73ºF) on average.

More about Mexico City

  • When it comes to searching for somewhere to rest your head, you'll find the most popular stays in Mexico City right here. Check out these hotels as soon as you've locked in your flight from McGhee Tyson Airport to Mexico City:

  • Chapultepec Park and Zocalo are a couple of top-rated attractions to put on your Mexico City to-do list. Keep the sightseeing going at National Museum of Anthropology.

Explore more of Mexico

  • Mexico City is always a good idea, but there are so many other corners of Mexico just waiting to be explored. About 467 kilometres west of Mexico City, a trip to Guadalajara will fill your itinerary to the brim. Don't miss top attractions like Teatro Degollado, Portales Tlaquepaque Park and Zoologico Guadalajara.

  • Around 105 kilometres south-east of Mexico City, Puebla is another essential stop in Mexico. Experience this destination's highlights firsthand at Mirador de Los Fuertes, Cuexcomate and Street of Candies.

Prices shown on this page are estimated lowest prices only. Found in the last 45 days.