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Cheap Flights from Knoxville to Rome

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Compare Knoxville to Rome flight deals

Find the cheapest month or even day of the year to fly to Rome

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Flight deals from Knoxville to Rome

Looking for a cheap last-minute deal or the best return flight from Knoxville to Rome? Find the lowest prices on one-way and return tickets right here.
Rome.R 4,479 per passenger.Departing Tue, 14 Oct.One-way flight with Allegiant Air.Outbound indirect flight with Allegiant Air, departs from Knoxville on Tue, 14 Oct, arriving in Rome Fiumicino.Price includes taxes and charges.From R 4,479, select.
Rome.R 7,064 per passenger.Departing Fri, 6 Jun.One-way flight with Allegiant Air.Outbound indirect flight with Allegiant Air, departs from Knoxville on Fri, 6 Jun, arriving in Rome Fiumicino.Price includes taxes and charges.From R 7,064, select.
Rome.R 8,731 per passenger.Departing Fri, 23 May.One-way flight with Allegiant Air.Outbound indirect flight with Allegiant Air, departs from Knoxville on Fri, 23 May, arriving in Rome Fiumicino.Price includes taxes and charges.From R 8,731, select.
Rome.R 9,368 per passenger.Departing Sat, 14 Mar.One-way flight with Delta.Outbound indirect flight with Delta, departs from Knoxville on Sat, 14 Mar, arriving in Rome Fiumicino.Price includes taxes and charges.From R 9,368, select.

Find the cheapest month to fly from Knoxville to Rome

We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Knoxville to Rome flights are currently cheapest in October.
May
from R 8,731
Jun
from R 7,064
Jul
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Aug
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Sep
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Oct
from R 4,479
Nov
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Dec
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Jan
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Feb
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Mar
from R 9,368
Apr
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Alternative Knoxville to Rome routes

Looking for the cheapest, fastest or easiest route from Knoxville to Rome? You could fly into the following airports instead.

Knoxville to Rome: Flight information

The things to know before you go.
Cheapest flight foundR 4,479
Cheapest month to flyOctober

Finding cheap flights from Knoxville to Rome: Frequently asked questions

There are 2 airports in Rome: Rome Ciampino and Rome Fiumicino.
The best price we found for a return flight from Knoxville to Rome is R 10,919. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.
Currently, there are no airlines that fly direct from Knoxville to Rome. But we found flights with one or more stops from R 10,919.
As of May 2025, there are no flights flying from Knoxville to Rome.
The cheapest month to fly from Knoxville to Rome is usually January.
If you're flying from Knoxville Airport, the cheapest airport near Rome is Rome Fiumicino – which is 22.9 km away from the centre of Rome. We've found flights into this airport from R 10,919.
After crunching the numbers on our flight calendar, we found that it's currently cheapest to fly from Knoxville Airport to Rome on Wednesday, 21 January 2026.
No airlines currently offer direct flights between Knoxville Airport and Rome. Most routes have one or more stops.
We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to Rome but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.
We crunched all the numbers in our flight calendar and it looks like the cheapest time to book a flight to Rome is around 40 days in advance, so don’t leave your flight to the last minute.
In May, the average temperature is usually around 18°C. August is typically the warmest month in Rome, when it usually averages around 30°C. You can expect the least rain in July. The coldest month is January, with temperatures averaging 5°C. The rainiest month is November.
Currently, Air France offers the cheapest flight tickets to Rome.

Flying from McGhee Tyson Airport (TYS) to Rome: what you need to know

  • Rome is five hours ahead of Knoxville, where McGhee Tyson Airport is located. Rome follows the UTC+1 timezone.

  • For stress-free travel, turn up at the airport two hours ahead of international flights and an hour before domestic departures. This ensures you have enough time to catch your TYS to Rome flight.

  • Heading away during a peak time like a bank holiday? Expect longer queues at security and check-in. Play it safe and arrive up to four hours before international flights and two hours before domestic departures.

  • TYS is around 18 kilometres from central Knoxville. If you're driving, catching a cab or ride-sharing from the centre, it'll take 20 minutes or so to get there, depending on traffic conditions.

  • Booked an early flight from McGhee Tyson Airport to Rome? Avoid the hassle of rushing to the airport (and sneak in some extra precious sleep) by choosing one of these hotels near TYS:

  • 78.98% of flights taking off from McGhee Tyson Airport touch down at their destination on time.

  • You'll find TYS at 2055 Alcoa Highway.

How to find the cheapest flights from McGhee Tyson Airport (TYS) to Rome

  • R 4,479 is the cheapest price we've found for a one-way McGhee Tyson Airport to Rome flight. A round-trip flight ticket right now is R 10,919. Depending on the availability when you book, these fares may change.

  • Booking in advance is often the key to finding a cheap flight from TYS to Rome. Fares tend to rise as seats fill up, so the closer you get to departure, the more it could cost you.

  • If you can be flexible with your trip dates, check out the 'Whole month' tool. It'll find the cheapest price across every month when searching for a McGhee Tyson Airport to Rome ticket.

  • Cut down on the time spent looking for cheap flights from TYS to Rome by creating a Price Alert. You'll get an email or notification on the app when a new low fare is offered.

  • Tailor your trip with filters. Choose your arrival and departure times, total journey duration and airlines. You can also sort results by 'Cheapest,' 'Fastest' or 'Best' flights from McGhee Tyson Airport to Rome.

Airports in Rome

Leonardo da Vinci-Fiumicino Airport (FCO)

  • Leonardo da Vinci-Fiumicino Airport (FCO) is around 32 kilometres from the centre of Rome. If you're getting a cab or a ride-share, the drive takes about 40 minutes.

  • When travelling on public transport, expect a journey time of around 50 minutes.

  • Consider booking a hotel close to FCO if you're coming in on a late flight from McGhee Tyson Airport to Rome. Select one of these options and make your first night all about rest:

  • Go wherever you want, whenever you want with a Leonardo da Vinci-Fiumicino Airport rental car. Book your wheels from Surprice, RentSmart24 or Noleggiare and discover more of Rome and beyond.

  • Lock in the lowest price by booking your vehicle from Leonardo da Vinci-Fiumicino Airport around three weeks in advance of your flight from TYS to Rome.

Ciampino-G. B. Pastine International Airport (CIA)

  • The centre of Rome is around 18 kilometres from Ciampino-G. B. Pastine International Airport (CIA). After your flight from McGhee Tyson Airport to Rome has touched down and you've made your way through the terminal, the drive should take about 40 minutes.

  • If you're travelling on public transport, it'll take around 1 hour 40 minutes.

  • After stepping off your TYS to Rome flight, tuck yourself in at a hotel near CIA. These are some comfortable options that'll help you switch to relaxation mode:

  • RentSmart24, Sicily by Car and Surprice make picking up a Ciampino-G. B. Pastine International Airport rental car simple. These providers are located in or around the terminal and will have you ready to go in a flash.

  • Get the lowest price by reserving your ride from CIA one week ahead of time. You'll also have access to a greater selection of vehicles.

Best time to go to Rome

  • Carefully consider your travel dates before securing your flight from McGhee Tyson Airport to Rome. The city comes alive during peak season, but prices are generally higher and attractions can get crowded. Visit Rome in the off-season if you want a more relaxed vibe.

  • Lock in a McGhee Tyson Airport to Rome flight ticket with a departure in August if you want to explore the city during its warmest month. Expect temperatures to range from 20ºC (68ºF) to 33ºC (91ºF).

  • January sees average temperatures of between 2ºC (36ºF) and 14ºC (57ºF). Look for a cheap ticket from TYS to Rome around that time if you like cooler conditions.

More about Rome

  • When it comes to looking for somewhere to lay your head, you'll find the best stays in Rome right here. Browse these options once you've locked in your flight from McGhee Tyson Airport to Rome:

  • Every great journey has to include a little sightseeing. Trevi Fountain, Colosseum and Roman Forum are essential stops on your Rome itinerary.

Explore more of Italy

  • Rome is always a good idea, but there are so many other parts of Italy waiting to be discovered. Around 483 kilometres north-west of Rome, a trip to Milan will keep your itinerary packed. Check out popular attractions like Grande Museo del Duomo di Milano, Milan Cathedral and The Last Supper Museum.

  • Naples is another must-experience destination in Italy and is around 193 kilometres south-east of Rome. No trip is complete without dropping by National Archaeological Museum, Castel dell'Ovo and Royal Palace of Naples.

Plan the rest of your trip from Knoxville to Rome

Prices shown on this page are estimated lowest prices only. Found in the last 45 days.