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Cheap Flights from Destin-Ft Walton Beach to Knoxville

Compare Destin-Ft Walton Beach to Knoxville flight deals

Find the cheapest month or even day of the year to fly to Knoxville

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Flight deals from Destin-Ft Walton Beach to Knoxville

Looking for a cheap last-minute deal or the best return flight from Destin-Ft Walton Beach Airport to Knoxville Airport? If you want to travel next month, return fares start from R 1,385. Find the lowest prices on one-way and return tickets right here.
Knoxville.R 730 per passenger.Departing Sat, 1 Aug.One-way flight with Allegiant Air.Outbound direct flight with Allegiant Air departs from Destin-Ft Walton Beach on Sat, 1 Aug, arriving in Knoxville.Price includes taxes and charges.From R 730, select.
Knoxville.R 731 per passenger.Departing Thu, 10 Sep.One-way flight with Allegiant Air.Outbound direct flight with Allegiant Air departs from Destin-Ft Walton Beach on Thu, 10 Sep, arriving in Knoxville.Price includes taxes and charges.From R 731, select.
Knoxville.R 796 per passenger.Departing Thu, 3 Dec.One-way flight with Allegiant Air.Outbound direct flight with Allegiant Air departs from Destin-Ft Walton Beach on Thu, 3 Dec, arriving in Knoxville.Price includes taxes and charges.From R 796, select.
Knoxville.R 796 per passenger.Departing Mon, 12 Oct.One-way flight with Allegiant Air.Outbound direct flight with Allegiant Air departs from Destin-Ft Walton Beach on Mon, 12 Oct, arriving in Knoxville.Price includes taxes and charges.From R 796, select.
Knoxville.R 861 per passenger.Departing Sun, 1 Nov.One-way flight with Allegiant Air.Outbound direct flight with Allegiant Air departs from Destin-Ft Walton Beach on Sun, 1 Nov, arriving in Knoxville.Price includes taxes and charges.From R 861, select.
Knoxville.R 1,666 per passenger.Departing Sat, 25 Jul.One-way flight with Allegiant Air.Outbound direct flight with Allegiant Air departs from Destin-Ft Walton Beach on Sat, 25 Jul, arriving in Knoxville.Price includes taxes and charges.From R 1,666, select.

Find the cheapest month to fly from Destin-Ft Walton Beach to Knoxville

We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Destin-Ft Walton Beach to Knoxville flights are currently cheapest in August.
Jul
from R 1,666
Aug
from R 730
Sep
from R 731
Oct
from R 796
Nov
from R 861
Dec
from R 796
Jan
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Feb
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Mar
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Apr
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May
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Jun
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Direct flights from Destin-Ft Walton Beach to Knoxville

Destin-Ft Walton Beach to Knoxville: Alternative routes

Compare routes from Destin-Ft Walton Beach to Knoxville below. You may find an airport to fly into that's cheaper, faster, or easier than Knoxville.

Knoxville

18km from central Knoxville
ClosestCheapest
from R 730
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Destin to Knoxville: Flight information

The things to know before you go.
Cheapest flight foundR 730
Cheapest month to flyAugust
Average flight time1 hr, 22 mins
Most popular airlineAllegiant Air
Average flights per week3

Finding cheap flights from Destin-Ft Walton Beach to Knoxville: Frequently asked questions

The best price we found for a return flight from Destin-Ft Walton Beach to Knoxville is R 1,385. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.
1 hour and 22 minutes is the average flight time from Destin-Ft Walton Beach to Knoxville.
Allegiant Air flies direct from Destin-Ft Walton Beach to Knoxville.
As of July 2026, there are 3 flights per week flying from Destin-Ft Walton Beach to Knoxville.
The cheapest month to fly from Destin-Ft Walton Beach to Knoxville is usually August.
After crunching the numbers on our flight calendar, we found that it's currently cheapest to fly from Destin-Ft Walton Beach Airport to Knoxville Airport on Saturday, 1 August 2026.
Yes – the average flight time is 1 hour and 22 minutes.
We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to Knoxville but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.

We crunched all the numbers in our flight calendar and it looks like the cheapest time to book a flight to Knoxville is around 40 days in advance, so don’t leave your flight to the last minute.

Currently, Allegiant Air offers the cheapest flight tickets to Knoxville.

Flying from Destin-Ft Walton Beach Airport (VPS) to Knoxville Airport (TYS): what you need to know

  • Jump on a direct flight from Destin-Ft Walton Beach Airport to Knoxville Airport and you'll be in the air for an average of 1 hour 20 minutes.

  • Get to the airport on time so you don't miss your VPS to TYS flight. Be there at least two hours ahead for international flights and an hour early for domestic departures to prevent a last-minute sprint to your gate.

  • During popular months like July, you'll want to get to the airport earlier. Arrive two hours before domestic departures and four hours ahead of international flights when you travel during a peak period in general.

  • Flying into Knoxville (and then seeing more of the United States!) is a breeze with Allegiant Air. This popular carrier offers direct flights from Destin-Ft Walton Beach Airport to Knoxville Airport.

  • Allegiant Air tops the list for bookings on this route.

  • The most punctual carrier that offers VPS to TYS flights is Allegiant Air. Its services land as scheduled 71.43% of the time.

Handy information about Destin-Ft Walton Beach Airport (VPS)

  • Destin-Ft Walton Beach Airport gets top marks for its on-time performance. 82% of flights that depart VPS arrive at their destination as scheduled.

  • The journey from central Destin to Destin-Ft Walton Beach Airport is about 13 kilometres. Look up Google Maps for the quickest way to get there, whether you plan to drive or take public transport.

  • Get your flight from Destin-Ft Walton Beach Airport to Knoxville Airport off to a hassle-free start. Only a quick drive from VPS, stay at TownePlace Suites Fort Walton Beach-Eglin AFB and be well-rested for the trip ahead.

Arriving at Knoxville Airport (TYS)

  • If you're getting in on a late Destin-Ft Walton Beach Airport to Knoxville Airport flight, nothing tops the convenience of staying close to the terminal. Grab your luggage from the carousel and then be tucked up in bed shortly after at one of these hotels near TYS:

  • Grab a Knoxville Airport rental car and explore Knoxville and beyond with your own wheels. Budget, Alamo and Avis are well-known companies to choose from here.

  • Lock in the best rate by reserving your vehicle from Knoxville Airport around three weeks ahead of your departure.

When to fly to Knoxville Airport (TYS)

  • October is the most popular month for flights from Destin-Ft Walton Beach Airport to Knoxville Airport. For smaller crowds, go to Knoxville in March.

  • Book your flight from Destin-Ft Walton Beach Airport to Knoxville Airport for July if you'd like to visit Knoxville during its warmest month. Expect temperatures of between 17ºC (63ºF) and 32ºC (90ºF).

  • If you like cooler conditions, search for a cheap ticket from VPS to TYS in January. Average temperatures are between -6ºC (21ºF) and 11ºC (52ºF) then.

Explore more of the United States

  • You've done Knoxville, now it's time to discover other parts of the United States. Travel about 451 kilometres north to Columbus to check off its popular sights. From Franklin Park Conservatory and Botanical Gardens to Whetstone Park / Park of Roses and Ohio Theatre, you'll have a packed itinerary ahead.

  • Around 467 kilometres north-west of Knoxville, Indianapolis is another favourite stop in the United States. Experience the best of this destination with a visit to Lucas Oil Stadium, Eiteljorg Museum and The Children's Museum of Indianapolis.

Plan the rest of your trip from Destin to Knoxville

Prices shown on this page are estimated lowest prices only. Found in the last 12 days.