Cheap Flights from Cali to Panama City

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Flight deals from Cali to Panama City

Looking for a cheap last-minute deal or the best return flight from Cali to Panama City? Find the lowest prices on one-way and return tickets right here.

Find the cheapest month to fly from Cali to Panama City

We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Cali to Panama City flights are currently cheapest in September.

Direct flights from Cali to Panama City

Alternative Cali to Panama City routes

Looking for the cheapest, fastest or easiest route from Cali to Panama City? You could fly into the following airports instead.

Cali to Panama City: Flight information

The things to know before you go.
Cheapest flight foundR 2,029
Cheapest month to flySeptember
Average flight time1 hr, 28 mins
Most popular airlineCopa
Average flights per week61

Finding cheap flights from Cali to Panama City: Frequently asked questions

There are 3 airports in Panama City: Panama City Paitilla, Balboa and Panama City Tocumen International.
The best price we found for a return flight from Cali to Panama City is R 3,140. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.
1 hour and 28 minutes is the average flight time from Cali to Panama City.
Copa, KLM and United fly direct from Cali to Panama City.
As of May 2025, there are 61 flights per week flying from Cali to Panama City.
The cheapest month to fly from Cali to Panama City is usually May 2025.
If you're flying from Cali Airport, the cheapest airport near Panama City is Balboa – which is 4.9 km away from the centre of Panama City. We've found flights into this airport from R 3,140.
After crunching the numbers on our flight calendar, we found that it's currently cheapest to fly from Cali Airport to Panama City on Friday, 5 September 2025.
Yes – the average flight time is 1 hour and 28 minutes.
We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to Panama City but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.
We crunched all the numbers in our flight calendar and it looks like the cheapest time to book a flight to Panama City is around 40 days in advance, so don’t leave your flight to the last minute.
In May, the average temperature is usually around 28°C. May is typically the warmest month in Panama City, when it usually averages around 29°C. You can expect the least rain in February. The coldest month is October, with temperatures averaging 25°C. The rainiest month is June.
Currently, Wingo offers the cheapest flight tickets to Panama City.

Flying from Alfonso B. Aragon Airport (CLO) to Panama City: what you need to know

  • Jump on a direct flight from Alfonso B. Aragon Airport to Panama City and you'll be travelling for around 1 hour 40 minutes.

  • Panama City's timezone is UTC-5, which is the same as Cali (the location of Alfonso B. Aragon Airport).

  • The most popular route is from Alfonso B. Aragon Airport (CLO) to Tocumen International Airport (PTY). You can select from 29 services every week between these two airports. If you want to get on your way as soon as you can, the earliest flight from CLO to PTY is the 04:40 Copa Airlines service. If you prefer to leave later in the day, the last departure is at 18:16 with Copa Airlines.

  • To avoid missing your CLO to Panama City flight, allow plenty of time to check in and find your gate. Turning up two hours ahead of international departures and one hour before domestic flights is the general rule.

  • If you're heading away during a bank holiday or another peak period, allow for even more time. A good general rule is two hours ahead of domestic flights and up to four hours before international departures. Check-in and security lines will be longer.

  • Begin your trip at CLO and fly nonstop to Tocumen International Airport (PTY). That will be your arrival point when searching for Alfonso B. Aragon Airport to Panama City tickets.

  • Book your favourite seat with Copa Airlines. This popular carrier offers direct flights from Alfonso B. Aragon Airport to Panama City.

  • Think about adding a stopover to potentially find a cheaper flight ticket from CLO to Panama City. Simply deselect 'Direct flights only' during your search. Break up your journey by stopping at one of these airports:

    • El Dorado International Airport (BOG)

    • Jose Maria Cordova International Airport (MDE)

    • Rafael Nunez International Airport (CTG)

  • CLO is about 19 kilometres from central Cali. If you're ride-sharing, catching a cab or driving from the centre, it'll take 35 minutes or so to arrive, depending on the traffic.

  • Have an early flight from Alfonso B. Aragon Airport to Panama City? Stay somewhere near CLO, such as Hotel Royal Elim Internacional. Hotel Sin Escala will also put you moments from the check-in counter.

  • Of all flights leaving Alfonso B. Aragon Airport, 66.35% land on schedule at their destination.

How to find the cheapest flights from Alfonso B. Aragon Airport (CLO) to Panama City

  • R 2,029 is currently the lowest price for a one-way Alfonso B. Aragon Airport to Panama City flight. A return flight ticket starts from R 3,140. These prices can change based on demand.

  • Book one month before you want to fly. Pricing trends suggest that this is the ideal window for finding cheap flights from CLO to Panama City.

  • May is the best month for landing an awesome deal on Alfonso B. Aragon Airport to Panama City tickets. If you're looking to travel at a different time of year, the 'Whole month' tool will show you the lowest prices for every month.

  • You don't need to check back in every day to find out if fares have dropped when you set up a Price Alert. We'll let you know when there's an even bigger deal on cheap flights from CLO to Panama City.

  • Select your preferred departure and arrival times, number of stops and airlines with our filters. Then, sort the results for your flight from Alfonso B. Aragon Airport to Panama City by 'Best,' 'Fastest' or 'Cheapest.'

Airports in Panama City

Tocumen International Airport (PTY)

  • The distance from Tocumen International Airport (PTY) to central Panama City is roughly 21 kilometres. It'll take you around 20 minutes to reach the centre driving.

  • Travelling to the centre on public transport will take you around 1 hour 5 minutes.

  • Consider staying in a hotel near PTY if you have a late flight from Alfonso B. Aragon Airport to Panama City. Choose one of these accommodation options and avoid the hassle of a long transfer:

  • Pick up a Tocumen International Airport rental car and explore Panama City and beyond with your own wheels. Avis, Dollar and MEX are leading providers to choose from here.

  • Booking your vehicle from Tocumen International Airport about three weeks before your flight from CLO to Panama City can help you secure the lowest rate.

Marcos A. Gelabert International Airport (PAC)

  • Marcos A. Gelabert International Airport (PAC) is around 2 kilometres from central Panama City. After your flight from Alfonso B. Aragon Airport to Panama City, it'll take you around 5 minutes to get to the heart of the city in a cab or ride-share.

  • The trip will take about 25 minutes on public transport.

  • You'll find some great places to rest your head close to PAC. Unwind and get cosy after your CLO to Panama City flight at one of these well-located options:

  • Forget about inconvenient public transport timetables or cab lines. Grab a Marcos A. Gelabert International Airport rental car and blaze your own trail. Compare offers from Thrifty, Avis and Alamo.

  • Avoid paying extra. Booking your ride three weeks before your arrival at PAC can land you a better rate.

Panama Pacifico Airport (BLB)

  • Panama Pacifico Airport (BLB) is around 16 kilometres from central Panama City. It takes about 20 minutes to get to the city centre by car once you've stepped off your flight from Alfonso B. Aragon Airport to Panama City.

  • Enjoy a low-stress, comfortable start to your trip by choosing a hotel near BLB after your CLO to Panama City flight. Recover from a day of travel or simply take a moment to find your footing in a new city at:

  • Whether you're searching for a budget-friendly compact for solo travel or a full-size SUV to fit everyone and their gear, you'll find the right Panama Pacifico Airport rental car for you. Browse the types of wheels available from suppliers such as Sixt, Dollar and Thrifty.

  • About one week ahead of your flight from Alfonso B. Aragon Airport to Panama City is the ideal time to book your vehicle from BLB. You're likely to snag a better deal or even pick up some early bird discounts.

Best time to go to Panama City

  • Before scheduling your flights from Alfonso B. Aragon Airport to Panama City, consider which time of year works best for you. Peak season in Panama City offers a lively atmosphere and plenty of things to do, while the off-season means you'll get better deals on hotels and smaller crowds.

  • Lock in an Alfonso B. Aragon Airport to Panama City flight ticket with a departure in March if you're eager to experience the city during its warmest month. Expect temperatures to range from 21ºC (70ºF) to 32ºC (90ºF).

  • Look for cheap tickets from CLO to Panama City in February if you want to travel in cooler conditions. Temperatures are at their lowest then, ranging between 22ºC (72ºF) and 31ºC (88ºF) on average.

More about Panama City

  • When it comes to searching for somewhere to lay your head, you'll find the best places to stay in Panama City right here. Explore these hotels after locking in your flight from Alfonso B. Aragon Airport to Panama City:

  • Casco Viejo and Panama Canal Museum are a couple of top-rated attractions to put on your Panama City to-do list. Keep the momentum going by heading to Cinta Costera.

Explore more of Panama

  • You've visited Panama City, now it's time to explore other corners of Panama. Journey around 322 kilometres west to David to tick off its top sights. From Parque Cervantes to Altos del Rio Park and Coquito Hills Park, you'll have a packed itinerary ahead.

  • If you're ready to explore another well-known destination in Panama, consider Santiago de Veraguas, about 193 kilometres south-west of Panama City. Santiago the Apostle Cathedral, Santiago de Veraguas, The Church of Jesus Christ of Latter Day Saints and La Placita San Juan De Dios are among its highlights.

Prices shown on this page are estimated lowest prices only. Found in the last 45 days.