Cheap Flights from Minneapolis St Paul to Panama City

Return selected
Return selected
origin
Enter the city you're flying from, or choose from the options below
Include nearby airports
    selected
    destination
    . Enter your destination, or choose from the options below
    Include nearby airports
      selected
      Travellers and cabin class, 1 Adult, Economy

      Compare Minneapolis St Paul to Panama City flight deals

      Find the cheapest month or even day of the year to fly to Panama City

      Book the best Panama City fare with no extra fees

      Flight deals from Minneapolis St Paul to Panama City

      Looking for a cheap last-minute deal or the best return flight from Minneapolis St Paul Airport to Panama City? If you want to travel next month, return fares start from R 13,777. Find the lowest prices on one-way and return tickets right here.

      Find the cheapest month to fly from Minneapolis St Paul to Panama City

      We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Minneapolis St Paul to Panama City flights are currently cheapest in October.

      Alternative Minneapolis St Paul to Panama City routes

      Looking for the cheapest, fastest or easiest route from Minneapolis St Paul to Panama City? You could fly into the following airports instead.

      Minneapolis to Panama City: Flight information

      The things to know before you go.
      Cheapest flight foundR 6,337
      Cheapest month to flyOctober

      Finding cheap flights from Minneapolis St Paul to Panama City: Frequently asked questions

      There are 3 airports in Panama City: Panama City Paitilla, Balboa and Panama City Tocumen International.
      The best price we found for a return flight from Minneapolis St Paul to Panama City is R 11,308. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.
      Currently, there are no airlines that fly direct from Minneapolis St Paul to Panama City. But we found flights with one or more stops from R 11,308.
      As of August 2026, there are no flights flying from Minneapolis St Paul to Panama City.
      The cheapest month to fly from Minneapolis St Paul to Panama City is usually February.
      If you're flying from Minneapolis St Paul Airport, the cheapest airport near Panama City is Panama City Tocumen International – which is 17.9 km away from the centre of Panama City. We've found flights into this airport from R 11,308.
      After crunching the numbers on our flight calendar, we found that it's currently cheapest to fly from Minneapolis St Paul Airport to Panama City on Tuesday, 2 February 2027.
      No airlines currently offer direct flights between Minneapolis St Paul Airport and Panama City. Most routes have one or more stops.
      We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to Panama City but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.

      We crunched all the numbers in our flight calendar and it looks like the cheapest time to book a flight to Panama City is around 40 days in advance, so don’t leave your flight to the last minute.

      In August, the average temperature is usually around 27°C. May is typically the warmest month in Panama City, when it usually averages around 29°C. You can expect the least rain in February. The coldest month is October, with temperatures averaging 25°C. The rainiest month is June.
      Currently, United offers the cheapest flight tickets to Panama City.

      Travelling from Minneapolis-Saint Paul International Airport (MSP) to Panama City: what you need to know

      • The timezone in Panama City is UTC-5. The city is one hour ahead of Minneapolis, where Minneapolis-Saint Paul International Airport is located.

      • For stress-free travel, arrive at the airport two hours ahead of international flights and one hour before domestic departures. That way, you won't have to rush to board your MSP to Panama City flight.

      • Travelling during a popular month such as July? School holidays and other popular periods can mean longer queues and delays at check-in and security. Play it safe and get there up to four hours ahead of international flights and two hours before a domestic departure.

      • Think about adding a stopover to potentially land a cheaper plane ticket from MSP to Panama City. Simply deselect 'Direct flights only' during your search. Take a break (and maybe save some cash) by stopping at one of these connecting airports:

        • Miami International Airport (MIA)

        • Orlando International Airport (MCO)

        • Cancun International Airport (CUN)

      • Travelling from central Minneapolis to MSP takes around 25 minutes by public transport. If you ride-share, drive or take a taxi, you'll cover the 11 kilometres in 20 minutes or so, depending on traffic conditions.

      • Booked an early flight from Minneapolis-Saint Paul International Airport to Panama City? Avoid the hassle of rushing to the airport (and enjoy a little extra shut-eye) by choosing one of these stays close to MSP:

      • When it comes to Minneapolis-Saint Paul International Airport's on-time performance, data shows 77% of flights meet their scheduled arrival time.

      • MSP is located at 6040 28th Avenue South.

      How to find the cheapest flights from Minneapolis-Saint Paul International Airport (MSP) to Panama City

      • R 6,337 is currently the best price for a one-way Minneapolis-Saint Paul International Airport to Panama City flight. A return plane ticket starts from R 11,308. These fares may change depending on demand and availability.

      • Don't leave everything to the last moment. You're more likely to land cheap flights from MSP to Panama City if you book early. Airlines often offer some great early bird discounts.

      • If you have flexibility with your travel dates, use the 'Whole month' tool. It'll find the cheapest price across each month when looking for a Minneapolis-Saint Paul International Airport to Panama City ticket.

      • You don't need to keep checking in to find out if fares have dropped when you set up a Price Alert. We'll notify you when there's an extra saving on cheap flights from MSP to Panama City.

      • Tailor your flights with filters. Pick your preferred arrival and departure times, airlines and total journey duration. You can also sort the results by 'Fastest,' 'Best' or 'Cheapest' flights from Minneapolis-Saint Paul International Airport to Panama City.

      Airports in Panama City

      Panama City Tocumen International Airport (PTY)

      • Panama City Tocumen International Airport (PTY) is around 24 kilometres from the centre of Panama City. If you're getting a taxi or a ride-share, the drive will take roughly 35 minutes.

      • It typically takes 50 minutes if you're travelling by public transport.

      • Think about booking a hotel close to PTY if you're coming in on a late flight from Minneapolis-Saint Paul International Airport to Panama City. Check in to one of these options and make your first night all about rest:

      • Get the best deal by reserving your vehicle from Panama City Tocumen International Airport around three weeks before your flight from MSP to Panama City.

      Panama Pacifico International Airport (BLB)

      • After your flight from Minneapolis-Saint Paul International Airport to Panama City has arrived, you can make your way to the city centre in about 10 minutes by car. Central Panama City is roughly 6 kilometres from Panama Pacifico International Airport (BLB).

      • The journey will take roughly 20 minutes on public transport.

      • Place the 'Do not disturb' sign on your door and unwind at a hotel close to BLB. Here are a few options where you can take a load off after your MSP to Panama City flight:

      • Secure your first choice, not your last resort. Booking your ride from BLB one week ahead of time often means more savings and a wider choice of vehicles.

      Best time to go to Panama City

      • January is the most popular month for flights from Minneapolis-Saint Paul International Airport to Panama City. To escape the crowds, head to Panama City in September.

      • Before booking a Minneapolis-Saint Paul International Airport to Panama City plane ticket, think about the type of weather you enjoy. March is the warmest month in Panama City, with temperatures ranging from 21ºC (70ºF) to 32ºC (90ºF).

      • January has average temperatures of between 22ºC (72ºF) and 31ºC (88ºF). Search for a cheap ticket from MSP to Panama City around that time if you want to travel in cooler conditions.

      More about Panama City

      • Once you've booked your flight from Minneapolis-Saint Paul International Airport to Panama City, choose a hotel that puts you right where the action is. Make one of these accommodation options your base for exploring Panama City:

      • There are so many things to do and see in this city it can be hard to know where to start. Metropolitan Cathedral (Catedral Metropolitan), Casco Viejo and Independence Square are highlights which should feature on any good Panama City itinerary.

      Explore more of Panama

      • David is just one of the many cities in Panama waiting to be explored after you've experienced Panama City. Around 322 kilometres away to the west, top sights here include Museo Antropológico y Etnográfico Dr. Roberto De La Guardia, Raptors To The Rescue and Unachi Botanical garden.

      • Your journey through Panama wouldn't feel complete without exploring Santiago de Veraguas. Santiago the Apostle Cathedral, Santiago de Veraguas is just one of the highlights in this destination, which is about 193 kilometres southwest of Panama City.

      Prices shown on this page are estimated lowest prices only. Found in the last 12 days.