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Cheap Flights from Panama City to Chicago

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      Travellers and cabin class, 1 Adult, Economy
      Copa
      United
      EVA Air

      Compare Panama City to Chicago flight deals

      Find the cheapest month or even day of the year to fly to Chicago

      Book the best Chicago fare with no extra fees

      Flight deals from Panama City to Chicago

      Looking for a cheap last-minute deal or the best return flight from Panama City to Chicago? If you want to travel next month, return fares start from R 10,761. Find the lowest prices on one-way and return tickets right here.
      Chicago.R 5,495 per passenger.Departing Mon, 7 Sep.One-way flight with Copa.Outbound indirect flight with Copa, departs from Panama City Tocumen International on Mon, 7 Sep, arriving in Chicago O'Hare International.Price includes taxes and charges.From R 5,495, select.
      Chicago.R 5,799 per passenger.Departing Wed, 18 Nov.One-way flight with Wingo.Outbound indirect flight with Wingo, departs from Balboa on Wed, 18 Nov, arriving in Chicago O'Hare International.Price includes taxes and charges.From R 5,799, select.
      Chicago.R 6,099 per passenger.Departing Fri, 23 Oct.One-way flight with Copa.Outbound indirect flight with Copa, departs from Panama City Tocumen International on Fri, 23 Oct, arriving in Chicago O'Hare International.Price includes taxes and charges.From R 6,099, select.
      Chicago.R 6,391 per passenger.Departing Sun, 30 Aug.One-way flight with Copa.Outbound indirect flight with Copa, departs from Panama City Tocumen International on Sun, 30 Aug, arriving in Chicago O'Hare International.Price includes taxes and charges.From R 6,391, select.
      Chicago.R 6,634 per passenger.Departing Tue, 22 Dec.One-way flight with Wingo.Outbound indirect flight with Wingo, departs from Balboa on Tue, 22 Dec, arriving in Chicago O'Hare International.Price includes taxes and charges.From R 6,634, select.
      Chicago.R 8,664 per passenger.Departing Sun, 25 Apr.One-way flight with Copa.Outbound indirect flight with Copa, departs from Panama City Tocumen International on Sun, 25 Apr, arriving in Chicago O'Hare International.Price includes taxes and charges.From R 8,664, select.
      Chicago.R 8,698 per passenger.Departing Thu, 13 May.One-way flight with Copa.Outbound indirect flight with Copa, departs from Panama City Tocumen International on Thu, 13 May, arriving in Chicago O'Hare International.Price includes taxes and charges.From R 8,698, select.
      Chicago.R 10,635 per passenger.Departing Mon, 18 Jan.One-way flight with Copa.Outbound indirect flight with Copa, departs from Panama City Tocumen International on Mon, 18 Jan, arriving in Chicago O'Hare International.Price includes taxes and charges.From R 10,635, select.
      Chicago.R 11,792 per passenger.Departing Tue, 1 Sep.One-way flight with Copa.Outbound direct flight with Copa departs from Panama City Tocumen International on Tue, 1 Sep, arriving in Chicago O'Hare International.Price includes taxes and charges.From R 11,792, select.
      Chicago.R 12,107 per passenger.Departing Fri, 4 Dec.One-way flight with Copa.Outbound direct flight with Copa departs from Panama City Tocumen International on Fri, 4 Dec, arriving in Chicago O'Hare International.Price includes taxes and charges.From R 12,107, select.
      Chicago.R 12,107 per passenger.Departing Mon, 2 Nov.One-way flight with Copa.Outbound direct flight with Copa departs from Panama City Tocumen International on Mon, 2 Nov, arriving in Chicago O'Hare International.Price includes taxes and charges.From R 12,107, select.
      Chicago.R 12,107 per passenger.Departing Sun, 25 Apr.One-way flight with Copa.Outbound direct flight with Copa departs from Panama City Tocumen International on Sun, 25 Apr, arriving in Chicago O'Hare International.Price includes taxes and charges.From R 12,107, select.
      Chicago.R 12,107 per passenger.Departing Mon, 12 Oct.One-way flight with Copa.Outbound direct flight with Copa departs from Panama City Tocumen International on Mon, 12 Oct, arriving in Chicago O'Hare International.Price includes taxes and charges.From R 12,107, select.
      Chicago.R 12,115 per passenger.Departing Sat, 27 Mar.One-way flight with Copa.Outbound direct flight with Copa departs from Panama City Tocumen International on Sat, 27 Mar, arriving in Chicago O'Hare International.Price includes taxes and charges.From R 12,115, select.
      Chicago.R 12,145 per passenger.Departing Mon, 18 Jan.One-way flight with Copa.Outbound direct flight with Copa departs from Panama City Tocumen International on Mon, 18 Jan, arriving in Chicago O'Hare International.Price includes taxes and charges.From R 12,145, select.
      Chicago.R 12,155 per passenger.Departing Thu, 13 May.One-way flight with Copa.Outbound direct flight with Copa departs from Panama City Tocumen International on Thu, 13 May, arriving in Chicago O'Hare International.Price includes taxes and charges.From R 12,155, select.

      Find the cheapest month to fly from Panama City to Chicago

      We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Panama City to Chicago flights are currently cheapest in September.
      Aug
      from R 6,407
      Sep
      from R 5,510
      Oct
      from R 6,115
      Nov
      from R 5,814
      Dec
      from R 6,651
      Jan
      from R 10,662
      Feb
      Find prices
      Mar
      from R 12,146
      Apr
      from R 8,687
      May
      from R 8,720
      Jun
      Find prices
      Jul
      Find prices

      Direct flights from Panama City to Chicago

      Copa
      EVA Air
      United

      Alternative Panama City to Chicago routes

      Looking for the cheapest, fastest or easiest route from Panama City to Chicago? You could fly into the following airports instead.

      Chicago Midway

      14km from central Chicago
      Closest
      from R 6,493
      Search flights

      Chicago O'Hare International

      25km from central Chicago
      Cheapest
      from R 5,510
      Search flights

      Chicago Rockford

      127km from central Chicago
      from R 6,698
      Search flights

      Panama City to Chicago: Flight information

      The things to know before you go.
      Cheapest flight foundR 5,495
      Cheapest month to flySeptember
      Average flight time5 hrs, 41 mins
      Most popular airlineCopa
      Average flights per week42

      Finding cheap flights from Panama City to Chicago: Frequently asked questions

      There are 3 airports in Chicago: Chicago Midway, Chicago O'Hare International and Chicago Rockford.
      The best price we found for a return flight from Panama City to Chicago is R 6,771. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.
      5 hours and 41 minutes is the average flight time from Panama City to Chicago.
      Copa, United and EVA Air fly direct from Panama City to Chicago.
      As of August 2026, there are 42 flights per week flying from Panama City to Chicago.
      The cheapest month to fly from Panama City to Chicago is usually November.
      If you're flying from Panama City, the cheapest airport near Chicago is Chicago O'Hare International – which is 25.5 km away from the centre of Chicago. We've found flights into this airport from R 6,771.
      After crunching the numbers on our flight calendar, we found that it is currently cheapest to fly from Panama City to Chicago on Sunday, 1 November 2026.
      Yes – the average flight time is 5 hours and 41 minutes.
      We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to Chicago but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.

      We crunched all the numbers in our flight calendar and it looks like the cheapest time to book a flight to Chicago is around 40 days in advance, so don’t leave your flight to the last minute.

      In August, the average temperature is usually around 22°C. July is typically the warmest month in Chicago, when it usually averages around 26°C. You can expect the least rain in January. The coldest month is January, with temperatures averaging -8°C. The rainiest month is August.
      The cheapest airline that flies to Chicago is Avianca. And the cheapest airline that flies to Chicago O'Hare International Airport is Copa.

      Flying from Panama City to Chicago: what you need to know

      • Start your holiday planning by considering where you'll take off for your flight from Panama City to Chicago. Panama City Tocumen International Airport (PTY) and Balboa Airport (BLB) are Panama City's main airports.

      • Chicago O'Hare International Airport (ORD) and Chicago Midway Airport (MDW) are Chicago's major entry points.

      • The average time for a direct Panama City to Chicago flight is 5 hours 40 minutes.

      • The timezone in Chicago is UTC-6, which is one hour behind Panama City.

      • Panama City Tocumen International Airport (PTY) to Chicago O'Hare International Airport (ORD) is the most popular route between these two cities. There are 14 departures a week to choose from. If you have things to do before leaving, the last flight from Panama City to Chicago is with Copa Airlines at 18:45. Opt for the first PTY to ORD departure operated by Copa Airlines at 07:39 to make the most of your arrival in Chicago.

      • Leave plenty of time to get on your Panama City to Chicago flight. It's generally best to arrive two hours before international departures and an hour ahead for domestic flights.

      • During popular months like July, it's a good idea to get to the airport earlier. Plan to arrive two hours before a domestic departure and four hours ahead of an international flight whenever you're travelling during a peak period in general.

      How to find the cheapest flights from Panama City to Chicago

      • To find cheap Panama City to Chicago flights, book in advance. Airlines typically offer lower prices when flights are first released.

      • The 'Whole month' search tool will show you the cheapest plane tickets from Panama City to Chicago across the month. It's a good way to find a bargain if your trip dates are flexible.

      • Finding a cheap flight from Panama City to Chicago couldn't be easier with Price Alerts. All you need to do is create one of these automatic alerts and we'll get in touch when a better deal is available.

      • Find an affordable Panama City to Chicago flight with the help of our filters. Choose your ideal duration, number of stops and airlines, then sort the results by 'Cheapest' for the best deals.

      Flying from Panama City

      Panama City Tocumen International Airport (PTY)

      • If you're looking for a direct flight from Panama City to Chicago, you can leave from Panama City Tocumen International Airport (PTY). Travel from PTY to Chicago O'Hare International Airport (ORD) in one seamless journey.

      • Reserve your Panama City to Chicago plane tickets with Copa Airlines. This carrier is a top choice for direct flights from PTY.

      • Stopovers are the ideal opportunity to break up your trip — and maybe even tour another city. When browsing Panama City to Chicago flights leaving from Panama City Tocumen International Airport, uncheck the 'Direct flights only' box to see where you can visit along the way. Consider one of these popular options:

        • Atlanta Hartsfield-Jackson Airport (ATL)

        • Los Angeles International Airport (LAX)

        • Miami International Airport (MIA)

      • Located around 18 kilometres from central Panama City, PTY can be reached in about 35 minutes by car, depending on traffic. The journey by public transport takes roughly 50 minutes.

      • After a hassle-free start to your break? Stay near Panama City Tocumen International Airport. Whether you've booked an early flight from Panama City to Chicago or just don't want to be rushed, these hotels are perfect:

      • 88% of flights departing from Panama City Tocumen International Airport reach their destination according to schedule. With its impressive on-time stats, you're unlikely to be delayed when jetting out of PTY.

      Balboa Airport (BLB)

      • BLB is around 5 kilometres from central Panama City. It'll take 10 minutes or so to get to the airport by car from the city centre. Public transport takes roughly 20 minutes.

      • Get your holiday started early with an additional night away from home. Before catching your flight from Panama City to Chicago, kick back in one of these hotels close to Balboa Airport:

      • Balboa Airport has a strong track record for reliability and timeliness. 88% of flights leaving here make it to their final destination as planned.

      Arriving in Chicago

      Chicago O'Hare International Airport (ORD)

      • The distance from Chicago O'Hare International Airport (ORD) to central Chicago is approximately 26 kilometres. It takes around 30 minutes to get to the centre driving.

      • If you're travelling by public transport, expect a journey time of about 45 minutes.

      • If you're coming in on a late flight from Panama City to Chicago, few things beat the convenience of staying close to the terminal. Grab your bags from the carousel and then be showered and resting not long after at one of these accommodation options near ORD:

      • Travel at your own pace with a Chicago O'Hare International Airport rental car. Book your wheels from Routes Car Rentals, Dollar or Budget and chase adventure across Chicago and beyond.

      • To get the best deal, reserve your vehicle from Chicago O'Hare International Airport about four weeks in advance of your Panama City to Chicago flight.

      • ORD is located at 10000 West O'Hare.

      Chicago Midway Airport (MDW)

      • After your flight from Panama City to Chicago has touched down, you can make your way to the city centre in about 25 minutes by car. Central Chicago is roughly 14 kilometres from Chicago Midway Airport (MDW).

      • The journey will take approximately 30 minutes on public transport.

      • After your flight from Panama City to Chicago, rest your head at a hotel close to MDW. These are some great accommodation options that'll help you switch to relaxation mode:

      • No need to worry about public transport schedules or slow-moving taxi lines. Grab a Chicago Midway Airport rental car and take your trip in whatever direction you choose. Compare availability and rates from Dollar, Hertz and Budget.

      • Call dibs on the best options. Securing your ride from MDW four weeks in advance often means better deals and a wider choice of vehicles.

      • Chicago Midway Airport can be found at 5700 South Cicero.

      Chicago Rockford Airport (RFD)

      • Chicago Rockford Airport (RFD) is roughly 129 kilometres from central Chicago. It'll take you about 1 hour 40 minutes to reach the city centre in a taxi or ride-share once you've stepped off your flight from Panama City to Chicago.

      • Public transport can get you there in about 2 hours.

      • Whether you're looking for an economy for a solo trip or a roomy SUV to fit the whole crew comfortably, you'll find the right Chicago Rockford Airport rental car for you. Check out the types of wheels available from suppliers such as Budget, Alamo and National.

      • If you're looking for a specific kind of vehicle, booking early gives you a better shot at snagging what you want. Reserve your ride from RFD a few weeks ahead of your flight from Panama City to Chicago.

      • Chicago Rockford Airport's address is 2 Airport Cir.

      Best time to go to Chicago

      • March is the quietest month for flights from Panama City to Chicago, while July is the busiest. Find the ideal time to go to Chicago based on whether you prefer a laid-back vibe or a more bustling atmosphere.

      • The warmest month in Chicago is July, with temperatures ranging between 16ºC (61ºF) and 28ºC (82ºF). Book your Panama City to Chicago ticket then if that's your ideal forecast.

      • Search for cheap flights from Panama City to Chicago in January if you like travelling in cooler conditions. Temperatures are at their lowest then, ranging between -12ºC (10ºF) and 3ºC (37ºF) on average.

      More about Chicago

      Explore more of the United States

      • You've seen Chicago, now it's time to discover more of the United States. Journey around 451 kilometres southeast to Columbus to check off its leading sights. From Franklin Park Conservatory and Botanical Gardens to Columbus Park of Roses and Ohio Theatre, you'll have a packed itinerary ahead.

      • Around 257 kilometres southeast of Chicago, Indianapolis is another favourite stop in the United States. Experience major highlights starting with Lucas Oil Stadium, Eiteljorg Museum of American Indians and Western Art and The Children's Museum of Indianapolis.

      Plan the rest of your trip from Panama City to Chicago

      Prices shown on this page are estimated lowest prices only. Found in the last 12 days.