Cheap Flights from Panama City to Mendoza

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Flight deals from Panama City to Mendoza Airport

Looking for a cheap last-minute deal or the best return flight from Panama City to Mendoza? Find the lowest prices on one-way and return tickets right here.

Find the cheapest month to fly from Panama City to Mendoza

We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Panama City to Mendoza flights are currently cheapest in April.

Direct flights from Panama City to Mendoza

Panama City to Mendoza: Alternative routes

Compare routes from Panama City to Mendoza below. You may find an airport to fly into that's cheaper, faster, or easier than Mendoza.

Panama City to Mendoza: Flight information

The things to know before you go.
Cheapest flight foundR 5,534
Cheapest month to flyApril
Average flight time6 hrs, 41 mins
Most popular airlineCopa
Average flights per week8

Finding cheap flights from Panama City to Mendoza: Frequently asked questions

The best price we found for a return flight from Panama City to Mendoza is R 11,753. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.
6 hours and 41 minutes is the average flight time from Panama City to Mendoza.
Copa flies direct from Panama City to Mendoza.
As of March 2026, there are 8 flights per week flying from Panama City to Mendoza.
The cheapest month to fly from Panama City to Mendoza is usually May.
After crunching the numbers on our flight calendar, we found that it is currently cheapest to fly from Panama City to Mendoza Airport on Monday, 4 May 2026.
Yes – the average flight time is 6 hours and 41 minutes.
We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to Mendoza but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.
We crunched all the numbers in our flight calendar and it looks like the cheapest time to book a flight to Mendoza is around 40 days in advance, so don’t leave your flight to the last minute.

Travelling from Panama City to El Plumerillo International Airport (MDZ): What you need to know

  • There are a couple of main airports you can start your journey from in Panama City. Explore your options departing from Tocumen International Airport (PTY) or Panama Pacifico Airport (BLB) when organising your flight from Panama City to El Plumerillo International Airport (MDZ).

  • Take off on a direct Panama City to El Plumerillo International Airport flight and you'll be travelling for around 6 hours 40 minutes.

  • The timezone in Mendoza is UTC-3, which is two hours ahead of Panama City. El Plumerillo International Airport is located in Mendoza.

  • The most popular route is from Tocumen International Airport (PTY) to El Plumerillo International Airport (MDZ). You can choose from 5 direct services every week. Copa Airlines operates a 3:28pm departure between PTY and MDZ.

  • Arriving two hours before an international flight and one hour ahead of a domestic departure are travel rules worth sticking to. Show up at the airport on time to catch your flight from Panama City to MDZ.

  • If you're taking off during a bank holiday or other peak period, give yourself more time. Arrive two hours ahead of domestic flights and up to four hours before international departures. Queues at security and check-in will be longer.

Airports in Panama City

Tocumen International Airport (PTY)

  • Tocumen International Airport (PTY) makes it easy to travel directly to your destination. Nonstop flights from Panama City to El Plumerillo International Airport (MDZ) operate out of this terminal.

  • Copa Airlines is a well-known airline that operates direct flights from Panama City to El Plumerillo International Airport departing from PTY.

  • The preferred choice for passengers flying between PTY and MDZ is Copa Airlines.

  • With an impressive 93.62% of services arriving as scheduled, Copa Airlines is the leading carrier for punctuality on this route.

  • Stopovers offer a great opportunity to discover a new place or just have a break during your trip. When looking for a cheap flight from Panama City to MDZ, deselect 'Direct flights only' to check out all potential stops. Arturo Merino Benitez Airport (SCL) is one option when departing from Tocumen International Airport (PTY).

  • PTY is about 21 kilometres from central Panama City. If you're catching a cab, ride-sharing or driving from the centre, it'll take 20 minutes or so to get there, depending on the traffic. If you're using public transport, expect the travel time to be around 1 hour 5 minutes.

  • Want a stress-free start to your holiday? Stay near Tocumen International Airport. Whether you have an early flight from Panama City to El Plumerillo International Airport or prefer not to feel hurried, these hotels are just what you're after:

  • 86.03% of flights departing from Tocumen International Airport arrive at their destination on schedule. With its strong performance rating, you're unlikely to experience delays when flying out of PTY.

Marcos A. Gelabert International Airport (PAC)

  • Using public transport, you can travel from central Panama City to PAC in about 25 minutes. The terminal is roughly 2 kilometres away, and making the trip by car takes approximately 5 minutes.

  • Want to treat yourself to an extra night away before boarding your Panama City to MDZ flight? Relax in a hotel near Marcos A. Gelabert International Airport before your adventure officially begins. These stays are calling your name:

Panama Pacifico Airport (BLB)

  • Is around BLB 16 kilometres from central Panama City. The drive from the city centre to the airport takes about 20 minutes.

  • Sleep a little longer, move a little slower, and still make your Panama City to El Plumerillo International Airport flight with plenty of time to spare. These hotels near Panama Pacifico Airport make it a breeze to get to the terminal if you're flying out first thing:

  • BLB has an on-time performance rating of 86.75%. This means the majority of its flights land as expected and your trip runs like clockwork.

About El Plumerillo International Airport (MDZ)

  • The last thing you need is a lengthy journey to your hotel if you're getting in late on a flight from Panama City to El Plumerillo International Airport. Check in to one of these accommodation options near MDZ instead:

  • Explore without limits with an El Plumerillo International Airport rental car. Pick up a set of wheels from rentar low cost, CORDOBA RENT A CAR or Fit and see more of Mendoza and beyond.

  • Lock in the best deal by reserving your ride around three weeks before your Panama City to El Plumerillo International Airport flight.

Getting from El Plumerillo International Airport (MDZ) to central Mendoza

  • El Plumerillo International Airport to central Mendoza is about 13 kilometres. If you're renting a car or getting a cab, plan ahead to make your trip as easy as possible. Journey times may vary based on the time of day and traffic conditions.

  • When travelling on public transport, expect a journey of around 40 minutes.

How to find the cheapest flights from Panama City to El Plumerillo International Airport (MDZ)

  • The cheapest price we've found for a one-way ticket from Panama City to El Plumerillo International Airport is R 5,534. For a return flight on this route, the best price is R 11,753. Depending on the availability and when you book, these fares could change.

  • Book three months before you travel. Research into pricing trends suggests this is the ideal window for finding cheap flights from Panama City to MDZ.

  • August is when you're most likely to find a fantastic deal on a Panama City to El Plumerillo International Airport ticket. If you need to travel during a different time of year, the 'Whole month' tool will give you the lowest prices across every month.

  • Save time searching for cheap plane tickets from Panama City to MDZ by creating a Price Alert. We'll send you an email or push notification on the app when prices go down.

  • Uncover a great deal on a flight from Panama City to El Plumerillo International Airport with the help of the filters. Pick your ideal departure and arrival times, airlines and number of stops. You can also sort your results by 'Fastest,' 'Cheapest' or 'Best.'

The best time to fly from Panama City to El Plumerillo International Airport (MDZ)

  • It's time to work out your travel dates for your flight from Panama City to El Plumerillo International Airport (MDZ). July is the peak month for travel to Mendoza. If you prefer a quieter vibe, think about going in April.

  • Lock in a Panama City to MDZ plane ticket departing in January if you want to visit the city during its warmest month. Expect temperatures in Mendoza to range from 17ºC (63ºF) to 32ºC (90ºF).

  • July has temperatures of between 1ºC (34ºF) and 15ºC (59ºF). Look for cheap tickets from Panama City to El Plumerillo International Airport around that time if you want to travel in cooler conditions.

More about Mendoza

  • When it comes to searching for somewhere to rest your head, you'll find the most popular stays in Mendoza right here. Check out these hotels as soon as you've locked in your flight from Panama City to El Plumerillo International Airport:

  • There are so many things to explore in this city, it can be tricky to know where to start. Ciudad de mendoza, Fiesta Nacional de la Vendimia and Parque General San Martin are major attractions which should feature on any good Mendoza itinerary.

Explore more of Argentina

  • Mendoza has plenty going for it, but there are so many other corners of Argentina waiting to be discovered. Around 145 kilometres north of Mendoza, a visit to San Juan will keep you on the move. Start with leading sights like Plaza Espana, Mercado Artesanal and Museo Don Julio.

  • San Luis is another standout destination in Argentina and is around 225 kilometres east of Mendoza. No trip is complete without visiting Iglesia Catedral de San Luis, Plaza Independencia and Casa De Las Culturas.

Prices shown on this page are estimated lowest prices only. Found in the last 45 days.