Cheap Flights from Raleigh / Durham to Panama City

Compare Raleigh / Durham to Panama City flight deals

Find the cheapest month or even day of the year to fly to Panama City

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Flight deals from Raleigh / Durham to Panama City

Looking for a cheap last-minute deal or the best return flight from Raleigh / Durham Airport to Panama City? If you want to travel next month, return fares start from R 8,948. Find the lowest prices on one-way and return tickets right here.

Panama City.R 4,642 per passenger.Departing Fri, 21 Aug.One-way flight with jetBlue.Outbound indirect flight with jetBlue, departs from Raleigh / Durham on Fri, 21 Aug, arriving in Panama City Tocumen International.Price includes taxes and charges.From R 4,642, select.

Panama City.R 4,728 per passenger.Departing Sun, 11 Oct.One-way flight with Frontier Airlines.Outbound indirect flight with Frontier Airlines, departs from Raleigh / Durham on Sun, 11 Oct, arriving in Panama City Tocumen International.Price includes taxes and charges.From R 4,728, select.

Panama City.R 4,797 per passenger.Departing Fri, 4 Sep.One-way flight with Frontier Airlines.Outbound indirect flight with Frontier Airlines, departs from Raleigh / Durham on Fri, 4 Sep, arriving in Panama City Tocumen International.Price includes taxes and charges.From R 4,797, select.

Panama City.R 5,666 per passenger.Departing Tue, 28 Jul.One-way flight with Frontier Airlines.Outbound indirect flight with Frontier Airlines, departs from Raleigh / Durham on Tue, 28 Jul, arriving in Panama City Tocumen International.Price includes taxes and charges.From R 5,666, select.

Panama City.R 5,885 per passenger.Departing Sun, 17 Jan.One-way flight with Breeze Airways.Outbound indirect flight with Breeze Airways, departs from Raleigh / Durham on Sun, 17 Jan, arriving in Panama City Tocumen International.Price includes taxes and charges.From R 5,885, select.

Panama City.R 7,039 per passenger.Departing Fri, 2 Apr.One-way flight with jetBlue.Outbound indirect flight with jetBlue, departs from Raleigh / Durham on Fri, 2 Apr, arriving in Balboa.Price includes taxes and charges.From R 7,039, select.

Panama City.R 10,420 per passenger.Departing Fri, 21 Aug.One-way flight with Copa.Outbound direct flight with Copa departs from Raleigh / Durham on Fri, 21 Aug, arriving in Panama City Tocumen International.Price includes taxes and charges.From R 10,420, select.

Panama City.R 10,427 per passenger.Departing Wed, 28 Oct.One-way flight with Copa.Outbound direct flight with Copa departs from Raleigh / Durham on Wed, 28 Oct, arriving in Panama City Tocumen International.Price includes taxes and charges.From R 10,427, select.

Panama City.R 10,427 per passenger.Departing Mon, 9 Nov.One-way flight with Copa.Outbound direct flight with Copa departs from Raleigh / Durham on Mon, 9 Nov, arriving in Panama City Tocumen International.Price includes taxes and charges.From R 10,427, select.

Panama City.R 10,432 per passenger.Departing Wed, 2 Sep.One-way flight with Copa.Outbound direct flight with Copa departs from Raleigh / Durham on Wed, 2 Sep, arriving in Panama City Tocumen International.Price includes taxes and charges.From R 10,432, select.

Panama City.R 10,432 per passenger.Departing Fri, 17 Jul.One-way flight with Copa.Outbound direct flight with Copa departs from Raleigh / Durham on Fri, 17 Jul, arriving in Panama City Tocumen International.Price includes taxes and charges.From R 10,432, select.

Panama City.R 10,447 per passenger.Departing Fri, 8 Jan.One-way flight with Copa.Outbound direct flight with Copa departs from Raleigh / Durham on Fri, 8 Jan, arriving in Panama City Tocumen International.Price includes taxes and charges.From R 10,447, select.

Panama City.R 10,473 per passenger.Departing Fri, 2 Apr.One-way flight with Copa.Outbound direct flight with Copa departs from Raleigh / Durham on Fri, 2 Apr, arriving in Panama City Tocumen International.Price includes taxes and charges.From R 10,473, select.

Panama City.R 11,486 per passenger.Departing Fri, 25 Dec.One-way flight with United.Outbound indirect flight with United, departs from Raleigh / Durham on Fri, 25 Dec, arriving in Panama City Tocumen International.Price includes taxes and charges.From R 11,486, select.

Panama City.R 11,731 per passenger.Departing Wed, 2 Dec.One-way flight with Copa.Outbound direct flight with Copa departs from Raleigh / Durham on Wed, 2 Dec, arriving in Panama City Tocumen International.Price includes taxes and charges.From R 11,731, select.

Find the cheapest month to fly from Raleigh / Durham to Panama City

We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Raleigh / Durham to Panama City flights are currently cheapest in August.

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Direct flights from Raleigh / Durham to Panama City

Alternative Raleigh / Durham to Panama City routes

Looking for the cheapest, fastest or easiest route from Raleigh / Durham to Panama City? You could fly into the following airports instead.

Durham to Panama City: Flight information

The things to know before you go.

Cheapest flight found	R 4,642
Cheapest month to fly	August
Average flight time	4 hrs, 31 mins
Most popular airline	Copa
Average flights per week	14

Finding cheap flights from Raleigh / Durham to Panama City: Frequently asked questions

How many airports are there in Panama City?

There are 3 airports in Panama City: Panama City Paitilla, Balboa and Panama City Tocumen International.

How much are return flights from Raleigh / Durham to Panama City?

The best price we found for a return flight from Raleigh / Durham to Panama City is R 8,948. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.

How long does it take to fly from Raleigh / Durham to Panama City?

4 hours and 31 minutes is the average flight time from Raleigh / Durham to Panama City.

Which airlines fly direct from Raleigh / Durham to Panama City?

Copa and United fly direct from Raleigh / Durham to Panama City.

How many flights are there a week from Raleigh / Durham to Panama City?

As of July 2026, there are 14 flights per week flying from Raleigh / Durham to Panama City.

When is the cheapest time to fly from Raleigh / Durham to Panama City?

The cheapest month to fly from Raleigh / Durham to Panama City is usually August.

Which is the cheapest airport to fly into in Panama City?

If you're flying from Raleigh / Durham Airport, the cheapest airport near Panama City is Balboa – which is 4.9 km away from the centre of Panama City. We've found flights into this airport from R 8,948.

Which upcoming date is cheapest to fly from Raleigh / Durham Airport to Panama City on?

After crunching the numbers on our flight calendar, we found that it's currently cheapest to fly from Raleigh / Durham Airport to Panama City on Wednesday, 19 August 2026.

Can I get a direct flight from Raleigh / Durham Airport to Panama City?

Yes – the average flight time is 4 hours and 31 minutes.

How can I get the best flight deal from Raleigh / Durham Airport to Panama City?

We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to Panama City but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.

When is the best time to book flights to Panama City?

We crunched all the numbers in our flight calendar and it looks like the cheapest time to book a flight to Panama City is around 40 days in advance, so don’t leave your flight to the last minute.

What’s the weather like in Panama City?

In July, the average temperature is usually around 27°C. May is typically the warmest month in Panama City, when it usually averages around 29°C. You can expect the least rain in February. The coldest month is October, with temperatures averaging 25°C. The rainiest month is June.

Which is the cheapest airline to fly from Raleigh / Durham Airport to Panama City with?

Currently, jetBlue and Copa offer the cheapest flight tickets to Panama City.

Travelling from Raleigh-Durham International Airport (RDU) to Panama City: what you need to know

The average length of a direct flight from Raleigh-Durham International Airport to Panama City is 4 hours 25 minutes.
Panama City and Durham (where Raleigh-Durham International Airport is located) are in the UTC-5 timezone. This means you won't need to account for any time differences.
Raleigh-Durham International Airport (RDU) to Panama City Tocumen International Airport (PTY) is the most popular route, with four weekly flights to pick from. You can travel from RDU to PTY at 15:08 with Copa Airlines.
Allow plenty of time to make your RDU to Panama City flight. It's generally best to arrive at least two hours before international departures and an hour ahead for domestic flights.
You can expect bigger queues during popular months like June. Arriving up to four hours in advance for international flights and two hours for domestic departures is a good idea.
Direct Raleigh-Durham International Airport to Panama City tickets are available for booking. Panama City Tocumen International Airport (PTY) will be where your journey ends.
Copa Airlines is a popular airline that operates direct flights from Raleigh-Durham International Airport to Panama City.
Consider adding a stopover to potentially find a cheaper plane ticket from RDU to Panama City. Simply uncheck 'Direct flights only' during your search. Take a break (and maybe save some cash) by stopping at one of these airports:
- Miami International Airport (MIA)
- Orlando International Airport (MCO)
- Fort Lauderdale-Hollywood International Airport (FLL)
RDU is around 16 kilometres from central Durham. If you're ride-sharing, catching a taxi or driving from the centre, it'll take you 20 minutes or so to get there, depending on traffic. If you're planning to take public transport, expect the trip time to be around 45 minutes.
Catching an early flight from Raleigh-Durham International Airport to Panama City? Avoid rushing to the airport (and get some extra shut-eye) by choosing one of these hotels close to RDU:
78% of flights that leave from Raleigh-Durham International Airport touch down at their destination on time.

How to find the cheapest flights from Raleigh-Durham International Airport (RDU) to Panama City

R 4,642 is currently the lowest price for a one-way Raleigh-Durham International Airport to Panama City flight. A return plane ticket starts from R 8,948. These prices may change depending on demand.
Book four months before you travel. Pricing trends show that this is the ideal window for finding cheap flights from RDU to Panama City.
The best month for picking up cheap Raleigh-Durham International Airport to Panama City tickets is September. Use the 'Whole month' tool to compare all available prices, then select the dates with the lowest fares.
There's no need to keep checking in to find out if fares have dropped when you create a Price Alert. We'll update you the moment there's an even bigger deal on cheap flights from RDU to Panama City.
Tailor your flights with filters. Choose your preferred arrival and departure times, airlines and total journey duration. You can also sort the results by 'Fastest,' 'Best' or 'Cheapest' flights from Raleigh-Durham International Airport to Panama City.

Airports in Panama City

Panama City Tocumen International Airport (PTY)

Panama City Tocumen International Airport (PTY) to the centre of Panama City takes about 35 minutes to reach by car. The centre is roughly 24 kilometres away.
Getting there by public transport takes about 50 minutes.
The last thing you want is a lengthy journey to your hotel if you're getting in late on a flight from Raleigh-Durham International Airport to Panama City. Reserve one of these accommodation options near PTY instead:
Reserving your ride from Panama City Tocumen International Airport around three weeks before your flight from RDU to Panama City can help you lock in the lowest rate.

Panama Pacifico International Airport (BLB)

Panama Pacifico International Airport (BLB) is about 6 kilometres from the centre of Panama City. Following your flight from Raleigh-Durham International Airport to Panama City, it'll take you around 10 minutes to reach the heart of the city in a ride-share or taxi.
If you're catching public transport, it'll take around 20 minutes.
You'll find some great places to park your luggage (and yourself) near BLB. Tuck yourself in and get cosy after your RDU to Panama City flight at one of these perfectly located options:
Lock in the best price by securing your ride from BLB one week in advance. You can also expect to have a wider range of vehicles.

Best time to go to Panama City

September is the quietest month for flights from Raleigh-Durham International Airport to Panama City, while January is the busiest. Work out the best time to visit Panama City based on whether you like a lively atmosphere or a more laid-back vibe.
When booking your Raleigh-Durham International Airport to Panama City plane ticket, think about what kind of weather you prefer. March is the warmest month in Panama City, with temperatures ranging from 21ºC (70ºF) to 32ºC (90ºF).
January sees average temperatures of between 22ºC (72ºF) and 31ºC (88ºF). Look for a cheap ticket from RDU to Panama City around that time if you'd rather travel in cooler conditions.

More about Panama City

Start your Panama City trip right by choosing the ideal place to stay. After booking your flight from Raleigh-Durham International Airport to Panama City, browse our range of hotels including:
There are so many things to explore in this city it can be difficult to know where to begin. Metropolitan Cathedral (Catedral Metropolitan), Casco Viejo and Independence Square are top sights which should feature on every Panama City itinerary.

Explore more of Panama

Panama City is easy to fall in love with, but there are so many other parts of Panama waiting to be explored. Around 322 kilometres west of Panama City, a trip to David will fill your itinerary to the brim. Start with popular sights like Museo Antropológico y Etnográfico Dr. Roberto De La Guardia, Raptors To The Rescue and Unachi Botanical garden.
Next stop? Set out for Santiago de Veraguas. It's located about 193 kilometres southwest of Panama City and features highlights like Santiago the Apostle Cathedral, Santiago de Veraguas.