Cheap Flights from Louisville Muhammad Ali International to Panama City

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Find the cheapest month to fly from Louisville Muhammad Ali International to Panama City

We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Louisville Muhammad Ali International to Panama City flights are currently cheapest in March.

Alternative Louisville Muhammad Ali International to Panama City routes

Looking for the cheapest, fastest or easiest route from Louisville Muhammad Ali International to Panama City? You could fly into the following airports instead.

Louisville to Panama City: Flight information

The things to know before you go.
Cheapest flight foundR 2,972
Cheapest month to flyMarch

Finding cheap flights from Louisville Muhammad Ali International to Panama City: Frequently asked questions

There are 3 airports in Panama City: Panama City Paitilla, Balboa and Panama City Tocumen International.
The best price we found for a return flight from Louisville Muhammad Ali International to Panama City is R 7,134. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.
Currently, there are no airlines that fly direct from Louisville Muhammad Ali International to Panama City. But we found flights with one or more stops from R 7,117.
As of February 2026, there are no flights flying from Louisville Muhammad Ali International to Panama City.
The cheapest month to fly from Louisville Muhammad Ali International to Panama City is usually March.
If you're flying from Louisville Muhammad Ali International Airport, the cheapest airport near Panama City is Panama City Tocumen International – which is 17.9 km away from the centre of Panama City. We've found flights into this airport from R 7,134.
After crunching the numbers on our flight calendar, we found that it's currently cheapest to fly from Louisville Muhammad Ali International Airport to Panama City on Thursday, 19 March 2026.
No airlines currently offer direct flights between Louisville Muhammad Ali International Airport and Panama City. Most routes have one or more stops.
We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to Panama City but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.
We crunched all the numbers in our flight calendar and it looks like the cheapest time to book a flight to Panama City is around 40 days in advance, so don’t leave your flight to the last minute.
In February, the average temperature is usually around 27°C. May is typically the warmest month in Panama City, when it usually averages around 29°C. You can expect the least rain in February. The coldest month is October, with temperatures averaging 25°C. The rainiest month is June.
Currently, United offers the cheapest flight tickets to Panama City.

Travelling from Louisville International Airport-Standiford Field (SDF) to Panama City: what you need to know

  • The timezone in Panama City is UTC-5. The city is one hour behind Louisville, where Louisville International Airport-Standiford Field is located.

  • For hassle-free travel, turn up at the airport two hours ahead of international flights and one hour before domestic departures. That way, you won't have to rush to catch your SDF to Panama City flight.

  • Travelling during a peak period like school or public holidays? Expect longer lines at security and check-in. To give yourself peace of mind, arrive up to four hours before international flights and two hours ahead of domestic departures.

  • A stopover is the ideal opportunity to take a break from travelling and possibly even visit a new city. When browsing for flight tickets from SDF to Panama City, uncheck the 'Direct flights only' box to see where you can visit along the way. Some popular options include:

    • Hartsfield-Jackson Atlanta International Airport (ATL)

    • Miami International Airport (MIA)

    • Tampa International Airport (TPA)

  • The journey from central Louisville to SDF takes around 2 hours 40 minutes by public transport. If you drive, ride-share or grab a cab, you'll cover the 14 kilometres in 25 minutes or so, depending on traffic conditions.

  • Have an early flight from Louisville International Airport-Standiford Field to Panama City? Avoid the stress of rushing to the terminal (and sneak in some extra snooze time) by choosing one of these hotels close to SDF:

  • 77.69% of flights leaving from Louisville International Airport-Standiford Field make it to their destination on time.

  • The address for SDF is 600 Terminal Drive.

How to find the cheapest flights from Louisville International Airport-Standiford Field (SDF) to Panama City

  • R 2,965 is the lowest price we've seen for a one-way Louisville International Airport-Standiford Field to Panama City flight. A return flight ticket right now is R 7,134. Depending on when you book and the availability, these fares can change.

  • To pick up cheap flights from SDF to Panama City, book as early as you can. Airlines typically offer their most competitively priced fares when tickets are first released.

  • The 'Whole month' search tool will show you the cheapest tickets from Louisville International Airport-Standiford Field to Panama City throughout the entire month. It's a good way to find a bargain if your travel dates are flexible.

  • Picking up a cheap flight from SDF to Panama City couldn't be easier with Price Alerts. Simply set up one of these automatic notifications and we'll notify you when a better deal is available.

  • Choose your preferred departure and arrival times, number of stops and airlines with our filters. Then, sort the results for your flight from Louisville International Airport-Standiford Field to Panama City by 'Cheapest,' 'Best' or 'Fastest.'

Airports in Panama City

Tocumen International Airport (PTY)

  • Tocumen International Airport (PTY) to central Panama City takes around 20 minutes by car. The centre is roughly 21 kilometres away.

  • Travelling to the centre on public transport will take you around 1 hour 5 minutes.

  • Consider staying in a hotel near PTY if you're coming in on a late flight from Louisville International Airport-Standiford Field to Panama City. Choose one of these options and avoid the hassle of a long transfer:

  • Pick up a Tocumen International Airport rental car and explore Panama City and beyond with your own wheels. Avis, Dollar and MEX are popular outlets to choose from here.

  • To lock in the lowest price, reserve your vehicle from Tocumen International Airport about three weeks ahead of your flight from SDF to Panama City.

Marcos A. Gelabert International Airport (PAC)

  • Marcos A. Gelabert International Airport (PAC) is around 2 kilometres from central Panama City. Following your flight from Louisville International Airport-Standiford Field to Panama City, it'll take you around 5 minutes to get to the heart of the city in a ride-share or cab.

  • Public transport will get you there in about 25 minutes.

  • There are some comfortable places to park your luggage (and yourself) near PAC. Tuck yourself in and get cosy after your SDF to Panama City flight at any of these well-located options:

  • Thrifty, Avis and Alamo make picking up a Marcos A. Gelabert International Airport rental car simple. These companies are located in or around the terminal and will have you on the road before long.

  • Don't pay more than you need to. Booking your ride three weeks before your arrival at PAC can land you a better rate.

Panama Pacifico Airport (BLB)

  • Make your way to the city centre after your flight from Louisville International Airport-Standiford Field to Panama City has landed. Central Panama City is about 16 kilometres from Panama Pacifico Airport (BLB) and takes roughly 20 minutes to reach by car.

  • If you don't want to make the journey to the centre, find a hotel near BLB. Check in to one of these stays after your SDF to Panama City flight:

  • Start your journey without stressing over how to get to your next stop with a Panama Pacifico Airport rental car. Book your wheels with trusted companies here like Sixt, Dollar and Thrifty.

  • Get a payoff by planning ahead. Book your ride from BLB one week before your flight from Louisville International Airport-Standiford Field to Panama City for the lowest prices.

Best time to go to Panama City

  • Before scheduling your flights from Louisville International Airport-Standiford Field to Panama City, consider which time of year works best for you. High season in Panama City offers a lively atmosphere and plenty of activities, while low season brings cheaper hotel deals and smaller crowds.

  • The warmest month in Panama City is March, with temperatures ranging between 21ºC (70ºF) and 32ºC (90ºF). Lock in your Louisville International Airport-Standiford Field to Panama City flight ticket then if you enjoy this type of weather.

  • February sees average temperatures of between 22ºC (72ºF) and 31ºC (88ºF). Look for a cheap ticket from SDF to Panama City around that time if you like travelling in cooler conditions.

More about Panama City

  • Start your Panama City trip right by choosing the perfect place to stay. After booking your flight from Louisville International Airport-Standiford Field to Panama City, check out our selection of hotels including:

  • Casco Viejo and Panama Canal Museum are just the start of the major attractions to put on your Panama City to-do list. Continue your sightseeing adventures at Cinta Costera.

Explore more of Panama

  • You've visited Panama City, now it's time to discover other corners of Panama. Travel around 322 kilometres west to David to check off its leading attractions. From Parque Cervantes to Altos del Rio Park and Coquito Hills Park, you'll have a full itinerary ahead.

  • If you're interested in discovering another corner of Panama, head for Santiago de Veraguas, about 193 kilometres south-west of Panama City. Santiago the Apostle Cathedral, Santiago de Veraguas, The Church of Jesus Christ of Latter Day Saints and La Placita San Juan De Dios are highlights.

Prices shown on this page are estimated lowest prices only. Found in the last 45 days.