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Cheap Flights from Madrid to Panama City

Compare Madrid to Panama City flight deals

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Flight deals from Madrid to Panama City

Looking for a cheap last-minute deal or the best return flight from Madrid to Panama City? Find the lowest prices on one-way and return tickets right here.
Panama City.R 5,108 per passenger.Departing Fri, 24 Apr.One-way flight with Avianca.Outbound indirect flight with Avianca, departs from Madrid on Fri, 24 Apr, arriving in Panama City Tocumen International.Price includes taxes and charges.From R 5,108, select.
Panama City.R 5,751 per passenger.Departing Tue, 24 Mar.One-way flight with Avianca.Outbound indirect flight with Avianca, departs from Madrid on Tue, 24 Mar, arriving in Panama City Tocumen International.Price includes taxes and charges.From R 5,751, select.
Panama City.R 5,751 per passenger.Departing Thu, 12 Feb.One-way flight with Avianca.Outbound indirect flight with Avianca, departs from Madrid on Thu, 12 Feb, arriving in Panama City Tocumen International.Price includes taxes and charges.From R 5,751, select.
Panama City.R 5,790 per passenger.Departing Thu, 7 May.One-way flight with Avianca.Outbound indirect flight with Avianca, departs from Madrid on Thu, 7 May, arriving in Panama City Tocumen International.Price includes taxes and charges.From R 5,790, select.
Panama City.R 5,805 per passenger.Departing Mon, 26 Jan.One-way flight with Avianca.Outbound indirect flight with Avianca, departs from Madrid on Mon, 26 Jan, arriving in Panama City Tocumen International.Price includes taxes and charges.From R 5,805, select.
Panama City.R 9,056 per passenger.Departing Tue, 2 Jun.One-way flight with Avianca.Outbound indirect flight with Avianca, departs from Madrid on Tue, 2 Jun, arriving in Panama City Tocumen International.Price includes taxes and charges.From R 9,056, select.
Panama City.R 9,139 per passenger.Departing Tue, 1 Sep.One-way flight with Avianca.Outbound indirect flight with Avianca, departs from Madrid on Tue, 1 Sep, arriving in Panama City Tocumen International.Price includes taxes and charges.From R 9,139, select.
Panama City.R 9,139 per passenger.Departing Mon, 17 Aug.One-way flight with Avianca.Outbound indirect flight with Avianca, departs from Madrid on Mon, 17 Aug, arriving in Panama City Tocumen International.Price includes taxes and charges.From R 9,139, select.
Map with a flight path from Madrid to Panama City. A plane icon is halfway along the route with a label that says "Direct flight".
Direct flight

Your route at a glance

Cheapest dealR 10,419
Cheapest monthApril
Average flight duration10 hours and 53 minutes
Most popular airlineIberia

Find the cheapest month to fly from Madrid to Panama City

We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Madrid to Panama City flights are currently cheapest in April.
Dec
from R 10,142
Jan
from R 5,805
Feb
from R 5,751
Mar
from R 5,751
Apr
from R 5,108
May
from R 5,790
Jun
from R 9,056
Jul
from R 11,168
Aug
from R 9,139
Sep
from R 9,139
Oct
from R 9,139
Nov
from R 9,139

Direct flights from Madrid to Panama City

Alternative Madrid to Panama City routes

Looking for the cheapest, fastest or easiest route from Madrid to Panama City? You could fly into the following airports instead.

Finding cheap flights from Madrid to Panama City: Frequently asked questions

There are 3 airports in Panama City: Panama City Paitilla, Balboa and Panama City Tocumen International.
The best price we found for a return flight from Madrid to Panama City is R 10,419. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.
10 hours and 53 minutes is the average flight time from Madrid to Panama City.
Copa, Etihad Airways and Air Europa fly direct from Madrid to Panama City.
As of December 2025, there are 55 flights per week flying from Madrid to Panama City.
The cheapest month to fly from Madrid to Panama City is usually April.
If you're flying from Madrid Airport, the cheapest airport near Panama City is Panama City Tocumen International – which is 17.9 km away from the centre of Panama City. We've found flights into this airport from R 10,419.
After crunching the numbers on our flight calendar, we found that it's currently cheapest to fly from Madrid Airport to Panama City on Sunday, 19 April 2026.
Yes – the average flight time is 10 hours and 53 minutes.
We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to Panama City but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.
We crunched all the numbers in our flight calendar and it looks like the cheapest time to book a flight to Panama City is around 40 days in advance, so don’t leave your flight to the last minute.
In December, the average temperature is usually around 27°C. May is typically the warmest month in Panama City, when it usually averages around 29°C. You can expect the least rain in February. The coldest month is October, with temperatures averaging 25°C. The rainiest month is June.
Currently, Avianca and Air Europa offer the cheapest flight tickets to Panama City.

Flying from Adolfo Suarez Madrid-Barajas Airport (MAD) to Panama City: what you need to know

  • Expect to be travelling for 9 hours 50 minutes. On average, that's the time it takes for a direct flight from Adolfo Suarez Madrid-Barajas Airport to Panama City.

  • Adolfo Suarez Madrid-Barajas Airport is located in Madrid. Based in the UTC-5 timezone, Panama City is six hours behind Madrid.

  • Adolfo Suarez Madrid-Barajas Airport (MAD) to Tocumen International Airport (PTY) is the most popular route, with ten flights a week to choose from. You can fly from MAD to PTY at 11:45 with Iberia.

  • To avoid missing your MAD to Panama City flight, leave enough time to navigate the airport and find your gate. Turning up two hours before international departures and an hour before domestic flights is the general rule.

  • Planning to travel during a peak period like school or public holidays? Expect longer lines at security and check-in. Play it safe and arrive up to four hours before international flights and two hours ahead of domestic departures.

  • Direct Adolfo Suarez Madrid-Barajas Airport to Panama City tickets are available for booking. Tocumen International Airport (PTY) will be where your journey ends.

  • Get on board with Air Europa. This well-known carrier offers direct flights from Adolfo Suarez Madrid-Barajas Airport to Panama City.

  • Consider adding a stopover to potentially score a cheaper flight ticket from MAD to Panama City. Simply deselect 'Direct flights only' during your search. Take a break (and maybe save some cash) by stopping at one of these airports:

    • Miami International Airport (MIA)

    • El Dorado International Airport (BOG)

    • Jose Maria Cordova International Airport (MDE)

  • Located around 13 kilometres from the centre of Madrid, MAD can be reached in about 25 minutes by car (depending on traffic). Travelling on public transport will take roughly 35 minutes.

  • Booked an early flight from Adolfo Suarez Madrid-Barajas Airport to Panama City? Avoid the last-minute rush to the terminal (and get some extra shut-eye) by choosing one of these hotels close to MAD:

  • When it comes to the on-time performance of Adolfo Suarez Madrid-Barajas Airport, data shows 78.23% of flights complete their journey on time.

How to find the cheapest flights from Adolfo Suarez Madrid-Barajas Airport (MAD) to Panama City

  • The lowest price we've seen for a one-way Adolfo Suarez Madrid-Barajas Airport to Panama City flight is R 5,108. The cheapest price for a return flight is R 10,419. Keep in mind fares may change due to demand at the time of booking.

  • To find cheap flights from MAD to Panama City, book as early as possible. Airlines generally offer lower prices when tickets first go on sale.

  • The 'Whole month' search tool will show you the cheapest tickets from Adolfo Suarez Madrid-Barajas Airport to Panama City across the entire month. It's a good way to snap up a bargain if your trip dates aren't set in stone.

  • Save time searching for cheap flights from MAD to Panama City by setting up a Price Alert. You'll receive an email or notification through the app when a new low fare is offered.

  • Save money on your flight from Adolfo Suarez Madrid-Barajas Airport to Panama City with the help of our filters. Choose your preferred duration, departure time and airlines, then sort the results by 'Cheapest' for the best deals.

Airports in Panama City

Tocumen International Airport (PTY)

  • Tocumen International Airport (PTY) to the centre of Panama City takes around 20 minutes by car. The centre is roughly 21 kilometres away.

  • It'll take around 1 hour 5 minutes if you're using public transport.

  • If you're coming in on a late flight from Adolfo Suarez Madrid-Barajas Airport to Panama City, nothing beats the convenience of staying near the terminal. Grab your bags from the carousel and then be showered and snoozing soon after at one of these accommodation options near PTY:

  • Grab a Tocumen International Airport rental car and discover Panama City and beyond with your own wheels. Avis, Dollar and MEX are popular providers to choose from here.

  • Secure the lowest price by reserving your ride from Tocumen International Airport about three weeks in advance of your flight from MAD to Panama City.

Marcos A. Gelabert International Airport (PAC)

  • Marcos A. Gelabert International Airport (PAC) is around 2 kilometres from central Panama City. Following your flight from Adolfo Suarez Madrid-Barajas Airport to Panama City, it'll take you around 5 minutes to reach the heart of the city in a ride-share or cab.

  • If you're catching public transport, it'll take around 25 minutes.

  • Following your MAD to Panama City flight, tuck yourself in at a hotel close to PAC. These are some great accommodation options that'll help you switch to relaxation mode:

  • No time to waste? The fastest way to get to where you're going is with a Marcos A. Gelabert International Airport rental car. Collect your wheels from Thrifty, Avis or Alamo and be on your way in a flash.

  • Score the best price by reserving your ride from PAC three weeks ahead of time. You can also expect to have a bigger selection of vehicles.

Panama Pacifico Airport (BLB)

  • Hop off your flight from Adolfo Suarez Madrid-Barajas Airport to Panama City and go straight to your hotel or start sightseeing right away. Central Panama City is around 16 kilometres from Panama Pacifico Airport (BLB) and usually takes 20 minutes to reach by car.

  • Enjoy a more relaxed start to your break by choosing a hotel near BLB after your MAD to Panama City flight. Unwind after a day of travel or just give yourself time to find your footing in a new place at:

  • Whether you're searching for a budget-friendly compact for a solo escape or a roomy SUV to transport your group, you'll find the right Panama Pacifico Airport rental car for you. Explore the types of wheels available from providers such as Sixt, Dollar and Thrifty.

  • Get a payoff by planning ahead. Book your ride from BLB one week before your flight from Adolfo Suarez Madrid-Barajas Airport to Panama City for the most affordable rates.

Best time to go to Panama City

  • Visit Panama City during high season if you like a busy atmosphere, but remember that prices are usually higher. Alternatively, book your flights from Adolfo Suarez Madrid-Barajas Airport to Panama City during the off-season when prices are cheaper and crowds are smaller.

  • The warmest month in Panama City is March, with temperatures ranging between 21ºC (70ºF) and 32ºC (90ºF). Lock in your Adolfo Suarez Madrid-Barajas Airport to Panama City flight ticket then if that's your definition of good weather.

  • If you'd rather travel in cooler conditions, look for a cheap ticket from MAD to Panama City in February when temperatures average between 22ºC (72ºF) and 31ºC (88ºF).

More about Panama City

  • After booking your flight from Adolfo Suarez Madrid-Barajas Airport to Panama City, find a hotel that offers both comfort and a great location. Make one of these accommodation options your base for exploring Panama City:

  • Every great journey has to include some sightseeing. Casco Viejo, Panama Canal Museum and Cinta Costera are must-visits when exploring Panama City.

Explore more of Panama

  • David is just one of the many places in Panama waiting to be discovered once you've seen the sights of Panama City. Around 322 kilometres away to the west, its top attractions include Parque Cervantes, Altos del Rio Park and Coquito Hills Park.

  • Around 193 kilometres south-west of Panama City, Santiago de Veraguas is another favourite stop in Panama. Experience this destination's highlights firsthand at Santiago the Apostle Cathedral, Santiago de Veraguas, The Church of Jesus Christ of Latter Day Saints and La Placita San Juan De Dios.

More travel options

Plan the rest of your trip from Madrid to Panama City

Prices shown on this page are estimated lowest prices only. Found in the last 45 days.