Cheap Flights from Panama City to Sao Paulo Guarulhos

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Flight deals from Panama City to Sao Paulo Guarulhos

Looking for a cheap last-minute deal or the best return flight from Panama City to Sao Paulo Guarulhos? Find the lowest prices on one-way and return tickets right here.

Find the cheapest month to fly from Panama City to Sao Paulo Guarulhos

We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Panama City to Sao Paulo Guarulhos flights are currently cheapest in July.

Direct flights from Panama City to Sao Paulo Guarulhos

Panama City to Sao Paulo Guarulhos: Alternative routes

Compare routes from Panama City to Sao Paulo below. You may find an airport to fly into that's cheaper, faster, or easier than Sao Paulo Guarulhos.

Panama City to Sao Paulo: Flight information

The things to know before you go.
Cheapest flight foundR 4,438
Cheapest month to flyJuly
Average flight time6 hrs, 56 mins
Most popular airlineCopa
Average flights per week213

Finding cheap flights from Panama City to Sao Paulo Guarulhos: Frequently asked questions

The best price we found for a return flight from Panama City to Sao Paulo Guarulhos is R 6,229. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.
6 hours and 56 minutes is the average flight time from Panama City to Sao Paulo Guarulhos.
Copa, GOL Linhas Aéreas and Azul Airlines fly direct from Panama City to Sao Paulo Guarulhos.
As of February 2026, there are 213 flights per week flying from Panama City to Sao Paulo Guarulhos.
The cheapest month to fly from Panama City to Sao Paulo Guarulhos is usually March.
After crunching the numbers on our flight calendar, we found that it is currently cheapest to fly from Panama City to Sao Paulo Guarulhos Airport on Saturday, 7 March 2026.
Yes – the average flight time is 6 hours and 56 minutes.
We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to Sao Paulo Guarulhos but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.
We crunched all the numbers in our flight calendar and it looks like the cheapest time to book a flight to Sao Paulo is around 40 days in advance, so don’t leave your flight to the last minute.
The cheapest airline that flies to Sao Paulo Guarulhos is Copa .

Travelling from Panama City to Sao Paulo-Guarulhos International Airport (GRU): What you need to know

  • Put your holiday plans into action by working out where you'll board your flight from Panama City to Sao Paulo-Guarulhos International Airport (GRU). Tocumen International Airport (PTY) and Panama Pacifico Airport (BLB) are the two main airports in Panama City.

  • 6 hours 45 minutes is the average travel time for a direct Panama City to Sao Paulo-Guarulhos International Airport flight.

  • Sao Paulo is two hours ahead of Panama City. Sao Paulo-Guarulhos International Airport is located in Sao Paulo, which follows the UTC-3 timezone.

  • With 35 direct weekly flights between the two airports, Tocumen International Airport (PTY) to Sao Paulo-Guarulhos International Airport (GRU) is the busiest route. Copa Airlines operates the earliest flight at 11:50am. If you prefer to get more out of your day before jetting off, the latest departure from PTY to GRU is with Copa Airlines at 10:01pm.

  • Your flight from Panama City to GRU won't wait if you're running late, so be at the airport on time. Arrive up to one hour in advance for domestic flights and two hours ahead when you're flying internationally.

  • If you're taking off during a bank holiday or other peak period, give yourself extra time. Get there two hours before domestic flights and up to four hours before international departures. Security and check-in lines will be longer.

Airports in Panama City

Tocumen International Airport (PTY)

  • You can jump on a direct flight from Panama City to Sao Paulo-Guarulhos International Airport (GRU) leaving from Tocumen International Airport (PTY).

  • You can get away on a direct flight from Panama City to Sao Paulo-Guarulhos International Airport with Copa Airlines. This popular airline offers services from PTY.

  • The majority of passengers choose to fly with Copa Airlines between PTY and GRU.

  • With 71.17% of services arriving as scheduled, Copa Airlines is the top on-time carrier on this route.

  • Stopovers are the ideal opportunity to break up your journey and possibly even tour another city. When searching for cheap flights from Panama City to GRU leaving from Tocumen International Airport (PTY), deselect the 'Direct flights only' box to get ideas for where to visit along the way. Top options include:

    • El Dorado International Airport (BOG)

    • Jorge Chavez International Airport (LIM)

    • Ministro Pistarini Airport (EZE)

  • PTY is about 21 kilometres from central Panama City. If you're driving, catching a cab or ride-sharing from the centre, it'll take you 20 minutes or so to get there, depending on the traffic. If you're taking public transport, expect the trip time to be around 1 hour 5 minutes.

  • Searching for a convenient hotel close to Tocumen International Airport? If you've booked an early flight from Panama City to Sao Paulo-Guarulhos International Airport, these accommodation options will have you sleeping moments from your departure lounge:

  • Tocumen International Airport earns top marks for on-time performance. 86.03% of flights that depart PTY arrive at their destination on time.

Marcos A. Gelabert International Airport (PAC)

  • PAC is around 2 kilometres from central Panama City. It'll take you 5 minutes or so to get to the airport by car from the city centre. Public transport takes approximately 25 minutes.

  • Start your holiday early with an additional night away from home. Before your Panama City to GRU flight, unwind in one of these hotels close to Marcos A. Gelabert International Airport:

Panama Pacifico Airport (BLB)

  • You can reserve a plane ticket from Panama City to Sao Paulo-Guarulhos International Airport (GRU) leaving from Panama Pacifico Airport (BLB) with a stopover. El Dorado International Airport (BOG) is a popular connection point.

  • If you're making your way to BLB from central Panama City, it'll take you around 20 minutes to arrive by car. The journey is roughly 16 kilometres.

  • Set yourself up for a smooth departure — stay near Panama Pacifico Airport and know you'll reach your gate with time to spare. Settle in at one of these hotels the day before if you have an early Panama City to Sao Paulo-Guarulhos International Airport flight:

  • With 86.75% of its departing flights arriving on time, BLB is a reliable starting point for your adventure.

About Sao Paulo-Guarulhos International Airport (GRU)

Getting from Sao Paulo-Guarulhos International Airport (GRU) to central Sao Paulo

  • Sao Paulo-Guarulhos International Airport is about 21 kilometres from central Sao Paulo. How long it'll take to get to the centre in a cab or car hire depends on the time of day. Do some research before your trip.

  • It'll take around 1 hour 20 minutes if you're using public transport.

How to find the cheapest flights from Panama City to Sao Paulo-Guarulhos International Airport (GRU)

  • The lowest price we've found for a one-way ticket from Panama City to Sao Paulo-Guarulhos International Airport is R 4,438. For a return flight on this route, the best price is R 6,229. Depending on when and how early you book, these fares may change.

  • Get cheap flights from Panama City to GRU by booking nine months ahead. Based on our research, that's the sweet spot for bagging a bargain.

  • The best month for finding cheap Panama City to Sao Paulo-Guarulhos International Airport tickets is February. Use the 'Whole month' tool to compare flight prices, then select the dates offering the lowest fares.

  • There's no need to check back in every day to find out if prices have dropped when you create a Price Alert. We'll let you know when a lower fare pops up on plane tickets from Panama City to GRU.

  • Filters make it easier to land a deal on your flight from Panama City to Sao Paulo-Guarulhos International Airport. Pick the departure times, carriers and stops that look good to you. Then sort the results by 'Cheapest' to find the lowest price right away.

The best time to fly from Panama City to Sao Paulo-Guarulhos International Airport (GRU)

  • May is the quietest month for flights from Panama City to Sao Paulo-Guarulhos International Airport (GRU), while July is the busiest. Choose the ideal time to go to Sao Paulo based on whether you want a lively atmosphere or a more laid-back vibe.

  • The warmest month in Sao Paulo is February, with temperatures ranging between 18ºC (64ºF) and 28ºC (82ºF). Lock in your Panama City to GRU plane ticket then if that's your idea of comfortable weather.

  • If you'd rather travel in cooler conditions, search for a cheap ticket from Panama City to Sao Paulo-Guarulhos International Airport in July when temperatures are between 12ºC (54ºF) and 25ºC (77ºF).

More about Sao Paulo

  • When it comes to searching for somewhere to lay your head, you'll find the best places to stay in Sao Paulo right here. Explore these hotels once you've locked in your flight from Panama City to Sao Paulo-Guarulhos International Airport:

  • Avenida Paulista and Ibirapuera Park are a couple of big attractions to put on your Sao Paulo must-do list. Keep the adventure rolling by checking out Pinacoteca Do Estado De Sao Paulo.

Explore more of Brazil

  • Ribeirao Preto is just one of the many places in Brazil waiting to be discovered once you've taken in the sights of Sao Paulo. Around 290 kilometres away to the north-west, its top attractions include Japanese Garden, Basílica de Santo Antônio de Pádua and Cristo Redentor, Parque Das Oliveiras.

  • Piracicaba is another sought-after destination in Brazil and is around 145 kilometres north-west of Sao Paulo. No trip is complete without dropping by Igreja Senhor Bom Jesus do Monte, Trees Park and Observatorio Astronomico Municipal.

Prices shown on this page are estimated lowest prices only. Found in the last 45 days.